Carboxyethylgermanium sesquioxide
- CAS No.
- 12758-40-6
- Chemical Name:
- Carboxyethylgermanium sesquioxide
- Synonyms
- ORGANIC GERMANIUM;BIS[2-CARBOXYETHYLGERMANIUM(IV)] SESQUIOXIDE;99.7%;GE 132;SK-818;Serocion;REPAGERMANIUM;proxigermanium;Germanium Ge 132;Germanium Sesquoxide
- CBNumber:
- CB2271237
- Molecular Formula:
- C6H10Ge2O7
- Molecular Weight:
- 339.37
- MDL Number:
- MFCD00049319
- MOL File:
- 12758-40-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 320°C |
|---|---|
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Aqueous Base (Sparingly) |
| form | Solid |
| pka | 3.6(at 25℃) |
| color | White to Off-White |
| Specific Gravity | 1.280 |
| Odor | wh. odorless powd. |
| Water Solubility | Slightly soluble in water. |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| Merck | 14,7795 |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | 1S/C6H10Ge2O7/c9-5(10)1-3-7(13)15-8(14)4-2-6(11)12/h1-4H2,(H,9,10)(H,11,12) |
| InChIKey | XEABSBMNTNXEJM-UHFFFAOYSA-N |
| SMILES | OC(=O)CC[Ge](=O)O[Ge](=O)CCC(O)=O |
| CAS DataBase Reference | 12758-40-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 1Q2P9TO9Q7 |
| EPA Substance Registry System | 2-(Carboxyethyl)germanium sesquioxide (12758-40-6) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H303-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UA2459750 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2931.90.9051 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Toxicity | LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz) | |||||||||
| NFPA 704 |
|
Carboxyethylgermanium sesquioxide price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 396265 | Bis(2-carboxyethylgermanium(IV) sesquioxide) 99% | 12758-40-6 | 5g | $90.4 | 2026-04-30 | Buy |
| TCI Chemical | B1367 | Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) | 12758-40-6 | 5g | $107 | 2026-04-30 | Buy |
| TCI Chemical | B1367 | Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) | 12758-40-6 | 25g | $353 | 2026-04-30 | Buy |
| TRC | TRC-B415290-1G | Bis(carboxyethylgermanium) Sesquioxide | 12758-40-6 | 1g | $78 | 2026-06-03 | Buy |
| Chem-Impex | 40578 | Bis[2-carboxyethylgermanium(IV)] sesquioxide ≥98%(Assaybytitration) | 12758-40-6 | 5G | $100.05 | 2026-05-19 | Buy |
Carboxyethylgermanium sesquioxide Chemical Properties, Uses, Production
Description
Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.
Originator
Sanwa Kagaku (Japan)
Uses
antifungal and antiseptic
Uses
Bis(2-carboxyethylgermanium(IV) sesquioxide) can be used as a precursor in the preparation of photoluminescent carbon dots, applicable as fluorescent probes in bioimaging applications.
Uses
A bifunctional metalloligand with metal-C (Ge-C) bonds,bis(carboxyethylgermanium) sesquioxide, has been used to make two metal-organometallic frameworks (MOMFs). bis-(carboxyethylgermanium)sesquioxide is a as a promising anti-oxidative agent. Bis(carboxyethylgermanium) sesquioxide induce INF-γ and has undergone clinical trials with promising preclinical results.
Definition
ChEBI: Propagermanium is an organogermanium compound.
brand name
Serosion
General Description
Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.
Safety Profile
Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.
Carboxyethylgermanium sesquioxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
| Adamas Reagent, Ltd. | 4006009262 13023226327 | hmj@titansci.com | China | 14098 | 59 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
View Latest Price from Carboxyethylgermanium sesquioxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | Carboxyethylgermanium sesquioxide
12758-40-6
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-07 | Bis(2-carboxyethylgermanium(IV) sesquioxide)
12758-40-6
|
1KG | 99.9 | 1KG 100KG | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2026-05-28 | Germanium Ge 132
12758-40-6
|
$1.70 | 10KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- Carboxyethylgermanium sesquioxide
12758-40-6
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Bis(2-carboxyethylgermanium(IV) sesquioxide)
12758-40-6
- 99.9
- Shaanxi Dideu Medichem Co. Ltd
-
- Germanium Ge 132
12758-40-6
- $1.70
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
