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Carboxyethylgermanium sesquioxide

CAS No.
12758-40-6
Chemical Name:
Carboxyethylgermanium sesquioxide
Synonyms
99.7%;GE 132;SK-818;Serocion;REPAGERMANIUM;proxigermanium;Germanium Ge 132;ORGANIC GERMANIUM;Germanium Sesquoxide;GERMANIUM SESQUIOXIDE
CBNumber:
CB2271237
Molecular Formula:
C6H10Ge2O7
Molecular Weight:
339.42
MDL Number:
MFCD00049319
MOL File:
12758-40-6.mol
MSDS File:
SDS
Last updated:2024-03-22 14:56:24

Carboxyethylgermanium sesquioxide Properties

Melting point 320°C
storage temp. -20°C Freezer, Under inert atmosphere
solubility Aqueous Base (Sparingly)
pka 3.6(at 25℃)
form Solid
color White to Off-White
Specific Gravity 1.280
Odor wh. odorless powd.
Water Solubility Slightly soluble in water.
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
Merck 14,7795
InChIKey XEABSBMNTNXEJM-UHFFFAOYSA-N
CAS DataBase Reference 12758-40-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1Q2P9TO9Q7
EPA Substance Registry System 2-(Carboxyethyl)germanium sesquioxide (12758-40-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H303-H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  2
RTECS  UA2459750
TSCA  Yes
HS Code  2931.90.9051
Toxicity LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz)
NFPA 704
1
0 0

Carboxyethylgermanium sesquioxide price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 396265 Bis(2-carboxyethylgermanium(IV) sesquioxide) 99% 12758-40-6 5g $82.4 2024-03-01 Buy
TCI Chemical B1367 Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) 12758-40-6 5g $86 2024-03-01 Buy
TCI Chemical B1367 Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) 12758-40-6 25g $283 2024-03-01 Buy
Alfa Aesar 036758 Bis(carboxyethylgermanium) sesquioxide, 99.7% 12758-40-6 5g $62.65 2024-03-01 Buy
Alfa Aesar 036758 Bis(carboxyethylgermanium) sesquioxide, 99.7% 12758-40-6 25g $208.65 2024-03-01 Buy
Product number Packaging Price Buy
396265 5g $82.4 Buy
B1367 5g $86 Buy
B1367 25g $283 Buy
036758 5g $62.65 Buy
036758 25g $208.65 Buy

Carboxyethylgermanium sesquioxide Chemical Properties,Uses,Production

Description

Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.

Originator

Sanwa Kagaku (Japan)

Uses

antifungal and antiseptic

Uses

Bis(2-carboxyethylgermanium(IV) sesquioxide) can be used as a precursor in the preparation of photoluminescent carbon dots, applicable as fluorescent probes in bioimaging applications.

Uses

A bifunctional metalloligand with metal-C (Ge-C) bonds,bis(carboxyethylgermanium) sesquioxide, has been used to make two metal-organometallic frameworks (MOMFs). bis-(carboxyethylgermanium)sesquioxide is a as a promising anti-oxidative agent. Bis(carboxyethylgermanium) sesquioxide induce INF-γ and has undergone clinical trials with promising preclinical results.

Definition

ChEBI: Propagermanium is an organogermanium compound.

brand name

Serosion

General Description

Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.

Safety Profile

Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.

Carboxyethylgermanium sesquioxide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 168)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7332 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8822 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58

View Lastest Price from Carboxyethylgermanium sesquioxide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Carboxyethylgermanium sesquioxide pictures 2024-03-23 Carboxyethylgermanium sesquioxide
12758-40-6
US $5.00-0.10 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Carboxyethylgermanium sesquioxide pictures 2023-08-18 Carboxyethylgermanium sesquioxide
12758-40-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Germanium Ge 132 pictures 2023-03-06 Germanium Ge 132
12758-40-6
US $1.70 / g/Bag 10g 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
  • Germanium Ge 132 pictures
  • Germanium Ge 132
    12758-40-6
  • US $1.70 / g/Bag
  • 99%
  • Hebei Guanlang Biotechnology Co,.LTD
ORGANIC GERMANIUM CARBOXYETHYLGERMANIUM SESQUIOXIDE BIS(CARBOXYETHYLGERMANIUM SESQUIOXIDE) BIS-BETA CARBOXYETHYLGERMANIUM SESQUIOXIDE BETA-CARBOXYETHYLGERMANIUM OXIDE BETA-CARBOXYETHYLGERMANIUM SESQUIOXIDE BIS[2-CARBOXYETHYLGERMANIUM(IV)] SESQUIOXIDE BIS(2-CARBOXYETHYLGERMANIUM SESQUIOXIDE) GERMANIUM SESQUIOXIDE GE 132 3,3'-(1,3-DIOXO-1,3-DIGERMOXANEDIYL)BISPROPIONIC ACID 3,3-(1,3-dioxo-1,3-digermoxanediyl)-bispropionic REPAGERMANIUM 99.7% GERMANIUMSESQUIOXIDE,POWDER proxigermanium 1-PHENYL-2-CARBOXYLETHYLGERMANIUMSESQUISULPHIDE Bis(carboxyethylgermanium) sesquioxide, 99.7% 2-Carboxyethylgermanium sesquioxide 3,3'-(1,3-Dioxo-1,3-digermoxanediyl)dipropionic acid Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis Serocion 3-Oxygermylpropionic acid polymer SK-818 3,3'-(1,3-Dioxo-1,3-digerma-2-oxapropane-1,3-diyl)bispropionic acid 3,3'-(1,3-Dioxodigermoxane-1,3-diyl)dipropionic acid GerManiuM Sesquioxide USP Bis(2-carboxyethylgermanium(IV) sesquioxide), 99.5% Germanium Sesquoxide organogermanium compound Bis[2-carboxyethylgermanium(IV)] Sesquioxide > Carboxyethylgermanium sesquioxide ISO 9001:2015 REACH Germanium Ge 132 Bis(2-carboxyethylgermanium(IV) sesquioxide),99.95% Dipropanoic acid germanium sequioxide 12758-40-6 OGeOCH2CH2CO2H2 C6H10O7Ge2 C6H10GeO7 Cell Signaling and Neuroscience Cell Biology BioChemical Ge (Germanium) Compounds Semimetal Compounds Classes of Metal Compounds Organometallic Reagents Others Organogermanium Immune Cell Signaling and Blood Immune System Regulation Immunomodulators and Antibiotics Nutritional Supplements Ge (Germanium) Compounds Classes of Metal Compounds Semimetal Compounds