ChemicalBook >> CAS DataBase List >>Di-o-tolylguanidine
Di-o-tolylguanidine
- CAS No.
- 97-39-2
- Chemical Name:
- Di-o-tolylguanidine
- Synonyms
- DTG;DOTG;NSC 473;DOTG（DT）;Nsc132023;VANAX DOTG;eveitedotg;usafa-6598;Anchor DOTG;Eveite DOTG
- CBNumber:
- CB2290261
- Molecular Formula:
- C15H17N3
- Molecular Weight:
- 239.32
- MDL Number:
- MFCD00008513
- MOL File:
- 97-39-2.mol
- MSDS File:
- SDS
Last updated:2023-11-13 16:15:56
| Melting point | 176-178 °C(lit.) |
|---|---|
| Boiling point | 371.98°C (rough estimate) |
| Density | 1.1000 |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.4560 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | water: soluble70mg/mL at 20°C |
| form | solid |
| pka | 10.32±0.10(Predicted) |
| color | White |
| Water Solubility | 70mg/L at 20℃ |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| LogP | 2.9 at 25℃ |
| CAS DataBase Reference | 97-39-2(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | 1,3-DI-O-TOLYLGUANIDINE |
| FDA 21 CFR | 177.2600 |
| EWG's Food Scores | 1 |
| FDA UNII | LL2P01I17O |
| NIST Chemistry Reference | Guanidine, 1,3-di-o-tolyl-(97-39-2) |
| EPA Substance Registry System | 1,3-Di-o-tolylguanidine (97-39-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301-H315-H317-H319-H335-H302 | |||||||||
| Precautionary statements | P261-P280a-P301+P310a-P305+P351+P338-P405-P501a-P264-P270-P301+P312+P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MF1400000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29252900 | |||||||||
| NFPA 704 |
|
Di-o-tolylguanidine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 207713 | 1,3-Di-o-tolylguanidine 99% | 97-39-2 | 5g | $30.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 207713 | 1,3-Di-o-tolylguanidine 99% | 97-39-2 | 100g | $36.68 | 2024-03-01 | Buy |
| TCI Chemical | D0953 | 1,3-Di-o-tolylguanidine >99.0%(T) | 97-39-2 | 25g | $32 | 2024-03-01 | Buy |
| TCI Chemical | D0953 | 1,3-Di-o-tolylguanidine >99.0%(T) | 97-39-2 | 500g | $163 | 2024-03-01 | Buy |
| Alfa Aesar | B25127 | 1,3-Di-o-tolylguanidine, 99% | 97-39-2 | 100g | $55.65 | 2024-03-01 | Buy |
Di-o-tolylguanidine Chemical Properties,Uses,Production
Description
DTG (97-39-2) is an agonist of the sigma (σ) receptor1?with roughly equal potency against both subtypes (σ1 and σ2 IC50’s ~ 30nM)2.
Uses
DTG is a selective ligand for the sigma-binding site. DTG has high binding affinity.
Definition
ChEBI: 1,2-bis(2-methylphenyl)guanidine is a member of toluenes.
General Description
1,3-Di-o-tolylguanidine is a selective σ-receptor agonist. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice.
Flammability and Explosibility
Non flammable
Biological Activity
Displays high and roughly equal affinity for both σ 1 and σ 2 receptors.
Safety Profile
Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
The guanidine crystallises from aqueous EtOH. The sulfate has m 253-254o(dec, H2O). [Beilstein 12 H 803, 12 II 445, 12 III 1871, 16 IV 1764]
References
1) Weber?et al.?(1986),?1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs; Proc. Natl. Acad. Sci. USA,?83?8784 2) Scherz?et al.?(1990),?Synthesis and Structure-Activity Relationships of N,N’-Di-o-tolylguanidine Analogues, High-Affinity Ligands for the Haloperidol-Sensitive σ Receptor; J. Med. Chem.,?33?2421
Di-o-tolylguanidine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 231)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12455 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 | sales@richfortunechem.com | China | 303 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Chemson Industrial (Shanghai) Co., Ltd. | 86-21-65208861- 8007 | sales1@chemson.com.cn | CHINA | 117 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from Di-o-tolylguanidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-11-13 | Di-o-tolylguanidine
97-39-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-26 | Di-o-tolylguanidine
97-39-2
|
US $40.00-9.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-09-06 | Di-o-tolylguanidine
97-39-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Di-o-tolylguanidine
97-39-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Di-o-tolylguanidine
97-39-2
- US $40.00-9.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Di-o-tolylguanidine
97-39-2
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
97-39-2(Di-o-tolylguanidine)Related Search:
2-Chlorobenzotrifluoride
2-Methylbenzotrifluoride
DI-ORTHO-TOLYLGUANIDINE SALT OF DICATECHOL BORATE
DI-ORTHO-TOLYLGUANIDINE SALT OF DICATECHOL BORATE
DI-ORTHO-TOLYLGUANIDINE SALT OF DICATECHOL BORATE,hydrogen bis[benzene-o-diolato(2-)-O,O']borate(1-), compound with N,N'-di-o-tolylguanidine (1:1)
1of4
2,2'-DIMETHYLIMINOCARBANILIDE
1,3-DI-ORTHOTOLYL-GUANIDINE
1,3-DI-O-TOLYLGUANIDINE
1,3-DI-(2-TOLYL)GUANIDINE
1,3-Di-o-tolylguanidine
DI-O-TOLYLGUANIDINE
DTG
DOTG
DITOLYGUANIDINE
N,N'-DI-ORTHO-TOLYLGUANIDINE
VANAX DOTG
1,3-Bis(o-tolyl)guanidine
1,3-di(2-tolyl)-guanidin
1,3-Di-o-tolyguanidine
NSC 473
1,3-di-o-tolyl-guanidin
1,3-ditolylguanidine
Accelerator DT
accelerator(dotg)
AcceleratorDOTG
Acrochem DOTG
Akrochem DOTG
Anchor DOTG
Diorthotolylguanidine
Dotg accelerator
dotgaccelerator
Ekaland DOTG
Eveite DOTG
eveitedotg
Guanidine, N,N'-bis(2-methylphenyl)-
n,n’-bis(2-methylphenyl)-guanidin
n,n’-bis(2-methylphenyl)guanidine
N,N’-bis(2-Methylphenyl)-Guanidine
n,n’-di-o-tolylguanidine
N,N'-Di-o-toluene guanidine
1,3-Ditolylguanidine,99%
1,3-Di(2-methylphenyl)guanidine
(vulcanization) accelrator DOTG
DiotolylGuanidine(Dotg)
N,N'-Bis(2-methylphenyl)guanidine
N,N'-Di-o-tolylguanidine
N,N-Di-O-tolylguanidine
Perkacit DOTG
USAF a-6598
usafa-6598
Vulkacit DOTG
Vulkacit dotg/C
vulkacitdotg
vulkacitdotg/c
Vulkacite DOTG
Guanidine, 1,3-di-o-tolyl-
Nsc132023
Ditolylguanidine
1,3-Di-o-tolylguanidine >
DOTG（DT）
97-39-2
CH3C6H4NH2CNH
AMINE