ChemicalBook >> CAS DataBase List >>ML364
ML364
- CAS No.
- 1991986-30-1
- Chemical Name:
- ML364
- Synonyms
- ML364;ML364, >98%;ML 364;ML-364;ML364 >=98% (HPLC);ML364, 1991986-30-1;ML364, 10 mM in DMSO;Deubiquitinase,Inhibitor,ML 364,DUBs,ML-364,ML364,inhibit;2-((4-Methylphenyl)sulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide;Benzamide, 2-[[(4-methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-
- CBNumber:
- CB23154506
- Molecular Formula:
- C24H18F3N3O3S2
- Molecular Weight:
- 517.54
- MDL Number:
- MFCD30718174
- MOL File:
- 1991986-30-1.mol
Last updated:2025-06-20 13:12:57
| Density | 1.457±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 20 mg/ml |
| form | A crystalline solid |
| pka | 6.51±0.50(Predicted) |
| color | Light yellow to yellow |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
ML364 price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1920 | ML364 ≥98% (HPLC) | 1991986-30-1 | 5 mg | $91.8 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML1920 | ML364 ≥98% (HPLC) | 1991986-30-1 | 25 mg | $297 | 2025-07-31 | Buy |
| Cayman Chemical | 21774 | ML-364 ≥98% | 1991986-30-1 | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 21774 | ML-364 ≥98% | 1991986-30-1 | 5mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 21774 | ML-364 ≥98% | 1991986-30-1 | 10mg | $176 | 2024-03-01 | Buy |
ML364 Chemical Properties,Uses,Production
Uses
ML364 is a small molecular inhibitor of the deubiquitinase USP2, which accelerates cyclin D1 degrdation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma.
Biological Activity
ML364 is a potent and specific inhibitor of the deubiquitinase USP2 th at induces cellular Cyclin D1 degradation in HCT116 colorectal cancer cells, followed by cell cycle arrest and apoptosis. Also, ML364 inhibits homologous recombination (HR)-mediated DNA repair.
ML364 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 91)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
1991986-30-1(ML364)Related Search:
ML364
ML364, 1991986-30-1
ML 364;ML-364
ML364, >98%
Benzamide, 2-[[(4-methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-
ML364 >=98% (HPLC)
2-((4-Methylphenyl)sulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide
Deubiquitinase,Inhibitor,ML 364,DUBs,ML-364,ML364,inhibit
ML364, 10 mM in DMSO
1991986-30-1
C24H18F3N3O3S2
