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4-Fluoroanisole

4-Fluoroanisole structure

CAS No.: 459-60-9

Chemical Name:: 4-Fluoroanisole

Synonyms: 1-FLUORO-4-METHOXYBENZENE;NSC 4672;4-Fluoranisol;p-fluoroanisol;4-FLUOROANISOL;4-fluoranisole;4-Floroanisole;P-FLUOROANISOLE;4-FLUOROANISOLE;Anisole, p-fluoro-

CBNumber:: CB2494904

Molecular Formula:: C7H7FO

Molecular Weight:: 126.13

MDL Number:: MFCD00000348

MOL File:: 459-60-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
4-Fluoroanisole 99%	F4602	25g	$55.3
4-Fluoroanisole >97.0%(GC)	F0231	25g	$31
4-Fluoroanisole >97.0%(GC)	F0231	500g	$227
4-Fluoroanisole	F587680	25g	$60
4-Fluoroanisole	012170	1g	$312
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4-Fluoroanisole Properties

Melting point	−45 °C(lit.)
Boiling point	157 °C(lit.)
Density	1.114 g/mL at 25 °C(lit.)
refractive index	n20/D 1.488(lit.)
Flash point	110 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Liquid
Specific Gravity	1.114
color	Clear colorless to light yellow
Water Solubility	Not miscible or difficult to mix in water.
BRN	1281425
InChI	1S/C7H7FO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3
InChIKey	VIPWUFMFHBIKQI-UHFFFAOYSA-N
SMILES	COc1ccc(F)cc1
CAS DataBase Reference	459-60-9(CAS DataBase Reference)
FDA UNII	F6A62M57LM
NIST Chemistry Reference	Benzene, 1-fluoro-4-methoxy-(459-60-9)
EPA Substance Registry System	p-Fluoroanisole (459-60-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02

Signal word

Warning

Hazard statements

H226

Precautionary statements

P210-P240-P241-P280a-P303+P361+P353-P501a

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 3271 3/PG 3

WGK Germany

Hazard Note

Flammable

TSCA

TSCA listed

HazardClass

PackingGroup

III

HS Code

29093090

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 3

Limited Quantities

5.0 L (1.3 gallons) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	2
1		0

4-Fluoroanisole price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	F4602	4-Fluoroanisole 99%	459-60-9	25g	$55.3	2026-04-30	Buy
TCI Chemical	F0231	4-Fluoroanisole >97.0%(GC)	459-60-9	25g	$31	2026-04-30	Buy
TCI Chemical	F0231	4-Fluoroanisole >97.0%(GC)	459-60-9	500g	$227	2026-04-30	Buy
TRC	F587680	4-Fluoroanisole	459-60-9	25g	$60	2021-12-16	Buy
Usbiological	012170	4-Fluoroanisole	459-60-9	1g	$312	2021-12-16	Buy

Product number	Packaging	Price	Buy
F4602	25g	$55.3	Buy
F0231	25g	$31	Buy
F0231	500g	$227	Buy
F587680	25g	$60	Buy
012170	1g	$312	Buy

4-Fluoroanisole Chemical Properties,Uses,Production

Synthesis

Fluorine itself reacts with a 4-substituted methoxy benzene tin derivative to give 4-fluoroanisole.

Chemical Properties

Colorless to light yellow liquid

Uses

An Acetanilide and Anisole derivative metabolite by liver.

Uses

4-Fluoroanisole is a raw material for medicine and intermediate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 1886, 1986 DOI: 10.1021/jo00360a042

4-Fluoroanisole synthesis

Synthesis of 4-Fluoroanisole from 4-Methoxyphenol

4-Fluoroanisole Preparation Products And Raw materials

Raw materials

3-Fluorobenzotrifluoride

Preparation Products

5-Fluoro-2-methoxyphenylboronic acid 2-FLUORO-5-HYDROXYBENZOIC ACID 2-Bromo-4-fluoroanisole 2-FLUORO-5-METHOXYBENZOIC ACID 2-Chloro-4-fluorophenol

Umbralisib 4-Fluorophenyl acetate 2-FLUORO-5-METHOXYBENZONITRILE 5-METHOXY-1H-INDAZOLE Benzenesulfonyl chloride, 5-fluoro-2-methoxy- (9CI)

2-CHLORO-6-FLUORO-3-METHOXYBENZALDEHYDE 2-Chloro-5'-fluoro-2'-hydroxy-acetophenone TIMTEC-BB SBB011556 JBQBYXOFVKGSKI-ONEGZZNKSA-N Butanoic acid, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-

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4-Fluoroanisole Suppliers

Global( 425)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Richest Group Ltd	58
Fuxin Pharmaceutical	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 4-Fluoroanisole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-22	4-Fluoroanisole 459-60-9	US $79.00-48.00 / mg		97.48%	10g	TargetMol Chemicals Inc.
2026-04-22	4-Fluoroanisole 459-60-9	US $79.00-48.00 / mg		97.48%	10g	TargetMol Chemicals Inc.
2026-03-20	4-Fluoroanisole 459-60-9	US $10.00 / KG	1KG	99%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd

4-Fluoroanisole
459-60-9
US $79.00-48.00 / mg
97.48%
TargetMol Chemicals Inc.

4-Fluoroanisole
459-60-9
US $79.00-48.00 / mg
97.48%
TargetMol Chemicals Inc.

4-Fluoroanisole
459-60-9
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Fluoroanisole Spectrum

4-Fluoroanisole(459-60-9)MS 4-Fluoroanisole(459-60-9)¹HNMR 4-Fluoroanisole(459-60-9)¹³CNMR 4-Fluoroanisole(459-60-9)IR1 4-Fluoroanisole(459-60-9)Raman

459-60-9(4-Fluoroanisole)Related Search:

1,2-Difluorobenzene 4-Fluorobenzoic acid Anisole 4-Bromofluorobenzene 4-Fluorobenzaldehyde

Florfenicol Transfluthrin 4-Fluorobenzyl alcohol 4-Fluoroacetophenone 4-Fluorophenylacetic acid

4-Fluorophenylacetyl chloride Fluorine 3-Fluoroanisole 99% 3,5-Difluoroanisole 2-BROMO-4-CHLORO-6-FLUOROANISOLE

3-BROMO-2-FLUOROANISOLE 2,3-Difluoroanisole 4-AMINO-2,6-FLUOROANISOLE

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P-FLUOROANISOLE 4-FLUOROANISOL 4-FLUOROANISOLE 4-METHOXYFLUOROBENZENE 1-fluoro-4-methoxy-benzen Anisole, p-fluoro- Benzene,1-fluoro-4-methoxy Benzene,1-fluoro-4-methoxy- p-fluoroanisol p-Fluoromethoxybenzene p-Fluorophenyl methyl ether p-Methoxyfluorobenzene 4-fluoranisole 4-Fluoroanisole,99% 4-Fluoranisol 1-Fluoro-4-methoxybenzene, 4-Fluorophenyl methyl ether 4-Fluoroanisole, 99% 25ML 4-Fluoroanisole≥ 99% (GC) 4-Fluoro-1-methoxybenzene 4-Fluorophenyl methyl ether 4-Methoxyphenyl fluoride 1-Methoxy-4-fluorobenzene 4-Methoxy-1-fluorobenzene 4-Floroanisole 4-FluoroMethoxybenzene NSC 4672 The fluorine benzene Methyl ether 4-Fluoroanisole (CAS No 459-60-9) 4-Fluoroanisole> 4-Fluoroanisole ISO 9001：2015 REACH 4-Fluoroanisole extrapure, 99% 1-FLUORO-4-METHOXYBENZENE P-Fluorobenzyl Ether 4-Fluoroanisole, 98% 459-60-9 459-56-1 459-60-6 Building Blocks Oxygen Compounds Organic Building Blocks Ethers Aromatics, Metabolites & Impurities Aromatics Metabolites & Impurities Fluorinated benzene series Aryl Fluorinated Building Blocks Building Blocks C2 to C7 C7-C8 Chemical Synthesis Fluorinated Building Blocks Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks Oxygen Compounds Benzene series AnisoleSeries Fluorobenzene