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4-Bromofluorobenzene

CAS No.
460-00-4
Chemical Name:
4-Bromofluorobenzene
Synonyms
1-BROMO-4-FLUOROBENZENE;BFB;4-FLUOROBROMOBENZENE;P-BROMOFLUOROBENZENE;PBFB;4-BROMO FLUORO BENZEN;4-Bromo-1-fluorobenzene;PARA FLUORO BROMO BENZENE;nsc10268;p-BrF-Ph
CBNumber:
CB9209307
Molecular Formula:
C6H4BrF
Molecular Weight:
175
MDL Number:
MFCD00000342
MOL File:
460-00-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:55:34

4-Bromofluorobenzene Properties

Melting point −16 °C(lit.)
Boiling point 150 °C(lit.)
Density 1.593 g/mL at 25 °C(lit.)
vapor pressure 4.99hPa at 25℃
refractive index n20/D 1.527(lit.)
Flash point 140 °F
storage temp. 2-8°C
solubility 0.136g/l
form Liquid
color Clear colorless
Water Solubility Soluble in water(0.14g/L).
BRN 774102
Henry's Law Constant 5.3×10-3 mol/(m3Pa) at 25℃, Hiatt (2013)
InChI 1S/C6H4BrF/c7-5-1-3-6(8)4-2-5/h1-4H
InChIKey AITNMTXHTIIIBB-UHFFFAOYSA-N
SMILES Fc1ccc(Br)cc1
LogP 3.018 at 25℃
CAS DataBase Reference 460-00-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII A7ZH69I3KH
NIST Chemistry Reference p-Bromofluorobenzene(460-00-4)
EPA Substance Registry System p-Bromofluorobenzene (460-00-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H332
Precautionary statements  P210-P304+P340+P312
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,F,Xn,T
Risk Statements  10-36/37/38-20-39/23/24/25-23/24/25-11-20/21/22
Safety Statements  26-36-37/39-16-45-36/37-7
RIDADR  UN 1993 3/PG 3
WGK Germany  1
RTECS  CY9033750
Hazard Note  Flammable/Irritant
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29036990
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
2 0

4-Bromofluorobenzene price More Price(77)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B67201 1-Bromo-4-fluorobenzene 99% 460-00-4 25g $27.9 2026-04-30 Buy
Sigma-Aldrich B67201 1-Bromo-4-fluorobenzene 99% 460-00-4 100g $68.5 2026-04-30 Buy
Sigma-Aldrich 48800 4-Bromofluorobenzene solution certified reference material, 25,000?μg/mL in methanol 460-00-4 1ML $82.7 2026-04-30 Buy
Sigma-Aldrich 48083 4-Bromofluorobenzene solution certifiedreferencematerial,2000?μg/mLinmethanol 460-00-4 1mL $39.1 2026-04-30 Buy
Sigma-Aldrich 442404 4-Bromofluorobenzene analytical standard 460-00-4 1000mg $27.6 2026-04-30 Buy
Product number Packaging Price Buy
B67201 25g $27.9 Buy
B67201 100g $68.5 Buy
48800 1ML $82.7 Buy
48083 1mL $39.1 Buy
442404 1000mg $27.6 Buy

4-Bromofluorobenzene Chemical Properties, Uses, Production

Chemical Properties

clear colorless liquid

Uses

1-Bromo-4-fluorobenzene is used as an intermediate in the synthesis of atypical antipsychotic agents.

Uses

4-Bromofluorobenzene can act like a surrogate standard for the:
determination of toxicity of diesel and water accommodated diesel fraction (WAF), towards microalgal species like Pseudokirchneriella subcapitata and Chlorella sp.MM3, using gas chromatography coupled with mass spectrometry (GC-MS).
determination of the chemicals like benzene, toluene, ethylbenzene and xylene (BTEX) and their stable carbon isotopic values, in gasoline contaminated ground-water, using gas chromatography coupled with mass spectrometry (GC-MS).

Uses

4-Bromofluorobenzene is a dihalogenated benzene used in the preparation of pharmaceutical compounds such as atypical antipsychotic agents.

Definition

ChEBI: 1-bromo-4-fluorobenzene is a member of the class of bromobenzenes that is bromobenzene carrying a fluoro atom at position 4. It is a member of bromobenzenes and a member of monofluorobenzenes.

General Description

Colorless liquid.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as 4-Bromofluorobenzene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

ACUTE/CHRONIC HAZARDS: Irritant.

Flammability and Explosibility

Flammable

823-85-8
460-00-4
Synthesis of 4-Bromofluorobenzene from 4-Fluorophenylhydrazine hydrochloride
Global Suppliers ( 771)
Supplier Tel Email Country ProdList Advantage
Yancheng Creator Chemical Co., Ltd. 0515-83072966 13016507129 yc@jssdchem.com China 20 58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 13396369453 18678026865 sdfantai@163.com China 904 58
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
Shandong Yukun Chemical Industry Co. LTD 18660690289 sales@yukunchem.com China 45 58
Fuxin Xin Kaida Fluorine Chemistry Co., Ltd. 0418-6566789 13464830066 sales@xkdchem.com China 174 58
Yancheng Longshen Chemical Co.,Ltd. 0515-88718898 18352070236 2355801706@qq.com China 100 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84

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1-bromo-4-fluoro-benzen 1-Fluoro-4-bromobenzene 4-Fluorobronibenzene Bromofluorobenzenecolorlessliq 4-Bromfluorbenzol 4-Fluorbrombenzol 4-Fluoro-1-bromobenzene 4-Fluorophenyl bromide 4-fluorophenylbromide BROMO FLUOROBENZENE P-FLUOROBROMOBENZENE 4-Bromoflourobenzene 4-Flourobromobenzene 4-BROMOFLUOROBENZENE 1X1ML METHANOL 1000 UG/ML 4-BROMOFLUOROBENZENE, 1000MG,NEAT 4-BROMOFLUOROBENZENE, 1X1ML, MEOH, 2000U G/ML p-Bromofluorobenzene,min.97% 1-bromo-4-fluorobenzene solution 4-Bromofluorobenzene99% PARA-BROMOFLUOROBENZENE 1-Brom-4-fluorbenzol 4-Bromofluorobenzene (1mg/ml in Methanol) [Internal standard for Water Analysis] 1-Bromo-4-fluorobenzene,99% 4-bromofluorobenzene (BFB) 1-Bromo-4-fluorobenzene Standard 4-Bromofluorobenzene≥ 99.5% (GC) Fluoride bromobenzene Benzene, 1-bromo-4-fluoro- Benzene,1-bromo-4-fluoro- nsc10268 p-Fluorophenyl bromide p-fluorophenylbromide EPA 8240B/8260A GC-MS Tuning Mix 4-BROMOFLUOROBENZENE p-Bromofluorobenzene, min. 97% 4-Bromophenyl fluoride 1-Bromo-4-fluorobenzene ,99.5% 4-Bromofluorobenzene 5g [460-00-4] 4-Fluorobromobenzene 99% 1-Bromo-4-fluorobenz 4-BroMofluorobenzene, 99% 100ML 4-BroMofluorobenzene, 99% 10ML 4-BroMo Flurobenzene The fluorine broMobenzene 4-BROMOFLUOROBENZENE, 1X1ML, MEOH, 25000 UG/ML p-Bromofluorobenzene@25 μg/mL in MeOH 4-BromofluorobenzeneSolution,10,000mg/L,1ml 4-BromofluorobenzeneSolution,50mg/L,1ml 4-BromofluorobenzeneSolution,250mg/L,1ml p-Bromofluorobenzene @0.2 mg/mL in MeOH 4-BromofluorobenzeneSolution,5,000mg/L,4ml p-Bromofluorobenzene@2.5 mg/mL in MeOH 4-BromofluorobenzeneSolution,2,000mg/L,1ml p-Bromofluorobenzene @2.0 mg/mL in MeOH 4-BromofluorobenzeneSolution,25mg/L,10ml p-Bromofluorobenzene@250 μg/mL in Methanol 4-BromofluorobenzeneSolution,25mg/L,5ml 4-BromofluorobenzeneSolution,2.50mg/L,10ml