2-P-ANISYL-1,3-INDANDIONE
- CAS No.
- 117-37-3
- Chemical Name:
- 2-P-ANISYL-1,3-INDANDIONE
- Synonyms
- andion;Miradon;spe2792;Unidone;SPE 2792;unidione;HSDB 3205;Andindione;Anisindone;nisindione
- CBNumber:
- CB2689681
- Molecular Formula:
- C16H12O3
- Molecular Weight:
- 252.26
- MDL Number:
- MFCD00176194
- MOL File:
- 117-37-3.mol
- MSDS File:
- SDS
Melting point | 156-157° |
---|---|
Boiling point | 355.44°C (rough estimate) |
Density | 1.1824 (rough estimate) |
refractive index | 1.5600 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly) |
form | Solid |
pka | pKa 4.13(H2O t=25.0±0.1 I=0.1(NaCl)) (Uncertain) |
color | White to Off-White |
EWG's Food Scores | 1 |
FDA UNII | S747T1ERAJ |
Proposition 65 List | Anisindione |
EPA Substance Registry System | Anisindione (117-37-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H351 | |||||||||
Precautionary statements | P264-P270-P308+P313-P301+P312+P330-P501 | |||||||||
RIDADR | 2811 | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
Toxicity | mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),Journal of Medicinal Chemistry. Vol. 28, Pg. 1591, 1985. | |||||||||
NFPA 704 |
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2-P-ANISYL-1,3-INDANDIONE price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A673480 | Anisindione | 117-37-3 | 1g | $120 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA29786 | Anisindione | 117-37-3 | 1g | $70 | 2021-12-16 | Buy |
Matrix Scientific | 063576 | 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione | 117-37-3 | 500mg | $95 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA29786 | Anisindione | 117-37-3 | 2g | $100 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA29786 | Anisindione | 117-37-3 | 5G | $200 | 2021-12-16 | Buy |
2-P-ANISYL-1,3-INDANDIONE Chemical Properties,Uses,Production
Chemical Properties
Slightly beige or yellow powder
Originator
Miradon,Schering,US,1960
Uses
radiopaque agent
Uses
Anisindione is a synthetic anticoagulant that prevents the formation of active procoagulation factors and proteins in the liver.
Definition
ChEBI: A cyclic beta-diketone consisting of indane-1,3-dione having a 4-methoxyphenyl substituent at the 4-position.
Manufacturing Process
To a hot solution of 20.6 g of sodium in 400 ml of absolute ethanol, there is added a solution of 110 g of phthalide and 110 g of p-methoxybenzaldehyde. A vigorous reaction ensues and one-half of the alcohol is distilled off over a two hour period. Ice and water are added to the red solution and the diluted solution is acidified with hydrochloric acid. The resulting gum solidifies and the aqueous phase is removed by decantation. The crude solid is recrystallized twice from two liters of ethanol yielding 2-(p-methoxyphenyl)-1,3-indandione as pale yellow crystals, MP 155-156°C.
brand name
Miradon (Schering).
Therapeutic Function
Anticoagulant
General Description
Anisindione, 2-(p-methoxyphenyl)-1,3-indandione, 2-(p-anisyl)-1,3-indandione (Miradon), is ap-methoxy congener of phenindione. It is a white, crystallinepowder, slightly soluble in water, tasteless, and absorbedwell after oral administration.
In instances when the urine may be alkaline, an orangecolor may be detected. This is caused by metabolic productsof anisindione and is not hematuria.
Purification Methods
Crystallise anisidinone from acetic acid or EtOH. [Horeau & Jacqius Bull Soc Chim Fr 53 1948, Koelsch J Am Chem. Soc 58 1331 1936, Beilstein 8 III 2931.]
2-P-ANISYL-1,3-INDANDIONE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8672 | 58 |
Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9407 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Nanjing Chemlin Chemical Co., Ltd | 025-83697070 | info@chemlin.com.cn | China | 19116 | 64 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
View Lastest Price from 2-P-ANISYL-1,3-INDANDIONE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-10-14 | 2-P-ANISYL-1,3-INDANDIONE
117-37-3
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
- 2-P-ANISYL-1,3-INDANDIONE
117-37-3
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.