2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
![2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID Structure](CAS/GIF/21801-79-6.gif)
- CAS No.
- 21801-79-6
- Chemical Name:
- 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
- Synonyms
- ASISCHEM C71528;BUTTPARK 9\05-56;3-Carboxy-2-methylimidazo[1,2-a]pyridine;2-methyl-3-imidazo[1,2-a]pyridinecarboxylate;2-a)pyridine-3-carboxylicacid,2-methyl-imidazo(;2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID;IMidazo[1,2-a]pyridine-3-carboxylic acid, 2-Methyl-;2-Methylimidazoó1,2-a!pyridine-3-carboxylic acid, 97%;2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid ,97%;2-methylimidazo[1,2-a]pyridine-3-carboxylic acid hydrochloride
- CBNumber:
- CB3201309
- Molecular Formula:
- C9H8N2O2
- Molecular Weight:
- 176.17
- MDL Number:
- MFCD00244615
- MOL File:
- 21801-79-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36-22 | |||||||||
| Safety Statements | 26-36/37/39-22 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,600mg/kg (600mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: IRRITABILITYBEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY),Journal of Medicinal Chemistry. Vol. 12, Pg. 122, 1969. | |||||||||
| NFPA 704 |
|
2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M643280 | 2-methylimidazo[1,2-a]pyridine-3-carboxylicacid | 21801-79-6 | 50mg | $60 | 2021-12-16 | Buy |
| AK Scientific | J96646 | 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid | 21801-79-6 | 1g | $65 | 2021-12-16 | Buy |
| AK Scientific | J96646 | 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid | 21801-79-6 | 250mg | $22 | 2021-12-16 | Buy |
| Apolloscientific | OR9488 | 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid | 21801-79-6 | 250mg | $23 | 2021-12-16 | Buy |
| AK Scientific | Y8284 | 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid | 21801-79-6 | 250mg | $29 | 2021-12-16 | Buy |
2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID Chemical Properties,Uses,Production
Chemical Properties
Pink solid
Synthesis
![2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER](/CAS/GIF/2549-19-1.gif)
2549-19-1
![2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID](/CAS/GIF/21801-79-6.gif)
21801-79-6
To a stirred ethyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate (2.00 g) solution of ethanol/water (1:1, 30 mL) was added lithium hydroxide (4.00 g) and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated to half of the original volume, followed by the slow addition of 6N hydrochloric acid at 0 °C and adjusting the pH to 6. The precipitated solid was collected by filtration and dried in a vacuum oven to afford 2-methylimidazo[1,2-a]pyridine-3-carboxylic acid (1.53 g, 88% yield) as an off-white solid.ESI-MS analysis showed the molecular ion peaks as 177 [M + H]+.
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 17, p. 7525 - 7545
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 15, p. 4223 - 4232
[3] Farmaco, Edizione Scientifica, 1982, vol. 37, # 1, p. 22 - 35
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 1870 - 1873
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5293 - 5305
2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49983 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
View Lastest Price from 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/c921d7a1-64c0-4068-acde-e4c2008c0c11.png) |
2020-01-08 | 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
21801-79-6
|
US $1.00 / g | 1g | 99.0% | 100kg | Career Henan Chemical Co | |
|
|
2020-01-08 | 4-Bromobenzaldehyde
1122-91-4
|
US $1.00 / ASSAYS | 1ASSAYS | 99.0% | 100kg | Career Henan Chemical Co |
-
- 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
21801-79-6
- US $1.00 / g
- 99.0%
- Career Henan Chemical Co
-
- 4-Bromobenzaldehyde
1122-91-4
- US $1.00 / ASSAYS
- 99.0%
- Career Henan Chemical Co
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