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(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine structure

CAS No.: 380499-07-0

Chemical Name:: (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

Synonyms: Desfluro Aprepitant;Aprepitant Impurity 6;Aprepitant Impurity 69;Aprepitant dehydro dealkyl;(R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine;(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine;2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-;(R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (Aprepitant Impurity)

CBNumber:: CB32542880

Molecular Formula:: C20H16F7NO2

Molecular Weight:: 435.34

MDL Number:

MOL File:: 380499-07-0.mol

Last updated:2023-04-23 13:52:06

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(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Properties

solubility	Chloroform, Ethyl Acetate
form	Solid
color	Off-White
FDA UNII	38EA8GN2BN

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B657140	(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine	380499-07-0	1mg	$155	2021-12-16	Buy
American Custom Chemicals Corporation	APN0002125	(2R)-2-[(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY]-3-(4-FLUOROPHENYL)-5,6-DIHYDRO-2H-1,4-OXAZINE 95.00%	380499-07-0	5MG	$502.61	2021-12-16	Buy

Product number	Packaging	Price	Buy
B657140	1mg	$155	Buy
APN0002125	5MG	$502.61	Buy

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of enantiomerically pure Aprepitant diastereomers and derivatives.

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Preparation Products And Raw materials

Raw materials

Preparation Products

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Suppliers

Global( 34)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-83725681-603		China	4505	50
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Nanjing XiZe Biotechnology CO., Ltd.	025-58362220 15250997978	1511893459@qq.com	China	7715	55
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@qq.com	China	7851	55
Shenzhen SUNGENING Bio-Medical Co., Ltd.	0755-28967200 13631290199	wxf@sungening.com	China	9506	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58

Supplier	Advantage
China National Standard Pharmaceutical Corporation Limited	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
Shanghai Kewel Chemical Co., Ltd.	50
Nanjing XiZe Biotechnology CO., Ltd.	55
BOC Sciences	65
Hubei Yangxin Medical Technology Co., Ltd.	55
Shenzhen SUNGENING Bio-Medical Co., Ltd.	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58

380499-07-0((2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine)Related Search:

1,1,1-Trimethoxy-2-chloroethane ent-Aprepitant (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Aprepitant Impurity 9 Aprepitant Impurity 6

Aprepitant Impurity A Enantiomer 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 19 [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol

Benzyl dihydrogen phosphate Aprepitant Fosaprepitant dimeglumine 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Fosaprepitant Impurity 5

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Aprepitant Aprepitant Impurity 11 HCl

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(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Aprepitant dehydro dealkyl Desfluro Aprepitant 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)- (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (Aprepitant Impurity) Aprepitant Impurity 69 Aprepitant Impurity 6 380499-07-0 C20H16F7NO2 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals