trans/cis Resveratrol-D4
- CAS No.
- 1089051-56-8
- Chemical Name:
- trans/cis Resveratrol-D4
- Synonyms
- trans/cis Resveratrol-D4;5-[(E)-2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)ethenyl]benzene-1,3-diol;Resveratrol D4Q: What is Resveratrol D4 Q: What is the CAS Number of Resveratrol D4 Q: What is the storage condition of Resveratrol D4 Q: What are the applications of Resveratrol D4
- CBNumber:
- CB32647480
- Molecular Formula:
- C14H8D4O3
- Molecular Weight:
- 232.267927112
- MDL Number:
- MOL File:
- 1089051-56-8.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H350 | |||||||||
Precautionary statements | P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501 | |||||||||
NFPA 704 |
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trans/cis Resveratrol-D4 price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 13130 | trans-Resveratrol-d4 ≥99% deuterated forms (d1-d4) | 1089051-56-8 | 100μg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 13130 | trans-Resveratrol-d4 ≥99% deuterated forms (d1-d4) | 1089051-56-8 | 250μg | $115 | 2024-03-01 | Buy |
Cayman Chemical | 13130 | trans-Resveratrol-d4 ≥99% deuterated forms (d1-d4) | 1089051-56-8 | 500μg | $216 | 2024-03-01 | Buy |
Cayman Chemical | 13130 | trans-Resveratrol-d4 | 1089051-56-8 | 1000μg | $380 | 2024-03-01 | Buy |
TRC | R150001 | Resveratrol-d4 | 1089051-56-8 | 10mg | $475 | 2021-12-16 | Buy |
trans/cis Resveratrol-D4 Chemical Properties,Uses,Production
Description
trans-Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-MS. trans-Resveratrol is a polyphenolic phytoalexin found in a variety of plants, including grapes, that has anti-inflammatory, antioxidant, and anticancer activities. It inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 μM, respectively), but not COX-2 (EC50s = >100 μM and 85 μM, respectively). trans-Resveratrol (3 and 8 mg/kg) inhibits carrageenan-induced paw edema in mice. It inhibits free radical formation in HL-60 human promyelocytic leukemia cells induced by phorbol 12-myristate 13-acetate (TPA; ; EC50 = 27 μM). trans-Resveratrol (1-25 μmol) reduces both the incidence and number of tumors in a two-stage mouse model of skin cancer induced by TPA and 7,12-dimethyl-benz[a]anthracene (DMBA). trans-Resveratrol (200 μM) also activates sirtuin 1 (SIRT1) by 8-fold in vitro and inhibits a variety of targets including ERK1, JNK1, Src, PKCα, aromatase/CYP19, and DNA polymerases α and δ (IC50s = 37, 50, 20, <10, 25, 3.3, and 5 μM, respectively) in vitro and/or ex vivo. It prolongs lifespan in model organisms including C. elegans, D. melanogaster, and mice.
Uses
Resveratrol-d4 is labelled Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.
trans/cis Resveratrol-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
trans/cis Resveratrol-D4 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |
Guangzhou Dreampharm Biotechnology Co., Ltd. | 020-36607679 17825480238 | 3008233717@qq.com | China | 9843 | 12 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Hubei Xinyang Medical Technology Co., Ltd | 15347293736 15347293736 | 2853117764@qq.com | China | 8594 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12584 | 58 |