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Shikalkin

CAS No.
54952-43-1
Chemical Name:
Shikalkin
Synonyms
shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
CBNumber:
CB3273506
Molecular Formula:
C16H16O5
Molecular Weight:
288.3
MDL Number:
MFCD00016668
MOL File:
54952-43-1.mol
MSDS File:
SDS
Last updated:2023-08-29 17:14:30

Shikalkin Properties

Melting point 144-145 °C
Boiling point 567.4±50.0 °C(Predicted)
Density 1.373±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility methanol: soluble1mg/mL
pka 7.34±0.20(Predicted)
form powder or solid
color red to brown
LogP 4.350 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H400
Precautionary statements  P273-P301+P312+P330
Hazard Codes  Xn,N
Risk Statements  22-50/53
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
NFPA 704
0
2 0

Shikalkin price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S7576 Shikonin ≥98% (HPLC) 54952-43-1 10mg $473 2024-03-01 Buy
Sigma-Aldrich S7576 Shikonin ≥98% (HPLC) 54952-43-1 50mg $1620 2024-03-01 Buy
TRC S357605 (±)-Shikonin 54952-43-1 5mg $85 2021-12-16 Buy
AK Scientific 0282AQ Shikonin 54952-43-1 10mg $162 2021-12-16 Buy
Arctom SY232843 (±)-Shikonin ≥98% 54952-43-1 10mg $74.45 2021-12-16 Buy
Product number Packaging Price Buy
S7576 10mg $473 Buy
S7576 50mg $1620 Buy
S357605 5mg $85 Buy
0282AQ 10mg $162 Buy
SY232843 10mg $74.45 Buy

Shikalkin Chemical Properties,Uses,Production

Uses

Shikonin has been used:

  • to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
  • as an inhibitor of renal aerobic glycosis and a potential
  • as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
  • to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death

Definition

ChEBI: C.I. Natural Red 20 is a naphthoquinone.

General Description

Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.

Biochem/physiol Actions

Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.

Shikalkin Preparation Products And Raw materials

Raw materials

Preparation Products

Shikalkin Suppliers

Global( 64)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577 gao490372054@gamil.com China 1250 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com China 19949 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Henan Allgreen Chemical Co.,LTD
+86-37155567971 +86-13633837469 info@allgreenchem.com China 5986 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58

View Lastest Price from Shikalkin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Shikalkin pictures 2024-04-12 Shikalkin
54952-43-1
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Shikalkin pictures 2023-02-24 Shikalkin
54952-43-1
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Shikalkin pictures
  • Shikalkin
    54952-43-1
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • Shikalkin pictures
  • Shikalkin
    54952-43-1
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione SHIKALKIN 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci) Arnebin-4 Nsc 291845 shiconin Shikonin (mixture of optical isomers, about 1:1) 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)- Shikonin >=98% (HPLC) (+-)-Shikonin (Rac)-Shikonin 5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione Inhibitor,inhibit,Shikalkin,(Rac) Shikonin,(Rac)Shikonin,(Rac)-Shikonin 54952-43-1 Inhibitors Coronavirus