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4-Dodecanolide

CAS No.
2305-05-7
Chemical Name:
4-Dodecanolide
Synonyms
GAMMA-DODECALACTONE;γ-Dodecalactone;dodecalactone;γ-dodecalactone,4-dodecanolide,dihydro-5-octyl-2(3H)-furanone;FEMA 2400;γ-Dodecanolide;4-DODECANOLIDE;G-DODECALACTONE;γ-Dodecalactone;Dodecanolide-1,4
CBNumber:
CB3427330
Molecular Formula:
C12H22O2
Molecular Weight:
198.3
MDL Number:
MFCD00036499
MOL File:
2305-05-7.mol
Last updated:2026-01-13 11:18:28
Product description Number Pack Size Price
γ-Dodecalactone natural, ≥98%, FG W240015 1 unit $61.5
γ-Dodecalactone natural, ≥98%, FG W240015 1 unit $61.5
γ-Dodecalactone natural, ≥98%, FG W240015 100g $205.2
γ-Dodecalactone natural, ≥98%, FG W240015 1kg $1064
γ-Dodecalactone ≥97%, FCC, FG W240001 1 unit $56.3
More product size

4-Dodecanolide Properties

Melting point 17-18 °C(lit.)
Boiling point 130-132 °C1.5 mm Hg(lit.)
Density 0.936 g/mL at 25 °C(lit.)
vapor pressure 7.3hPa at 20℃
refractive index n20/D 1.452(lit.)
FEMA 2400 | GAMMA-DODECALACTONE
Flash point >230 °F
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Sparingly), Methanol (Slightly)
form Oil
color Colourless
Specific Gravity 0.94
Odor at 100.00 %. fatty peach sweet metallic fruity
Odor Type fruity
biological source synthetic
Water Solubility 60mg/L at 20℃
JECFA Number 235
BRN 126680
Major Application flavors and fragrances
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C12H22O2/c1-2-3-4-5-6-7-8-11-9-10-12(13)14-11/h11H,2-10H2,1H3
InChIKey WGPCZPLRVAWXPW-UHFFFAOYSA-N
SMILES CCCCCCCCC1CCC(=O)O1
LogP 2.7 at 20℃
CAS DataBase Reference 2305-05-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) GAMMA-DODECALACTONE
EWG's Food Scores 1
FDA UNII YX9N4581LU
NIST Chemistry Reference «GAMMA» dodecalactone(2305-05-7)
EPA Substance Registry System 2(3H)-Furanone, dihydro-5-octyl- (2305-05-7)
UNSPSC Code 12164502
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  LU3600000
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29322090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicity skn-rbt 500 mg/24H MOD FCTXAV 14,751,76
NFPA 704
1
2 0

4-Dodecanolide price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W240015 γ-Dodecalactone natural, ≥98%, FG 2305-05-7 1 unit $61.5 2025-07-31 Buy
Sigma-Aldrich W240015 γ-Dodecalactone natural, ≥98%, FG 2305-05-7 1 unit $61.5 2025-07-31 Buy
Sigma-Aldrich W240015 γ-Dodecalactone natural, ≥98%, FG 2305-05-7 100g $205.2 2025-07-31 Buy
Sigma-Aldrich W240015 γ-Dodecalactone natural, ≥98%, FG 2305-05-7 1kg $1064 2025-07-31 Buy
Sigma-Aldrich W240001 γ-Dodecalactone ≥97%, FCC, FG 2305-05-7 1 unit $56.3 2025-07-31 Buy
Product number Packaging Price Buy
W240015 1 unit $61.5 Buy
W240015 1 unit $61.5 Buy
W240015 100g $205.2 Buy
W240015 1kg $1064 Buy
W240001 1 unit $56.3 Buy

4-Dodecanolide Chemical Properties,Uses,Production

Chemical Properties

γ-Dodecalactone has a fatty, peachy, somewhat musky odor and buttery, peach-like flavor

Occurrence

Reported found in apricot, cooked pork, milk products, peach, bilberry, guava fruit, papaya, pineapple, fresh blackberry, strawberry, celery leaves and stalks, celery root, blue cheeses, cheddar cheese, Swiss cheese, meats, beer, rum, mushrooms, plum brandy, quince, chervil, naranjilla fruit and other natural sources

Uses

4-Dodecanolide was one of the organic compounds from meat charbroiling operations studied. Finds some use in perfume compositions for fatty-fruity topnotes and long tenacity, e.g., in heavy floral fragrances. It is also used in combination with newer synthetic musks to produce exceptional tenacity and lasting sweetness in powdery and floral types. Used in flavour compositions, mainly in Butter, Butterscotch, Coconut, Tutti-frutti, Maple, Nut, Peach, Pineapple, etc.

Definition

ChEBI: Xi-Dihydro-5-octyl-2(3H)-furanone is a gamma-lactone.

Preparation

From 1-dodecen-12-oic acid with H2SO4 at 90°C; from 4-hydroxydodecanoic acid by lactonization; also from methylacrylate and octanol

Aroma threshold values

Detection: 7 ppb; aroma characteristics at 1.0%; sweet, creamy, fruity peach and apricot, lactonic, with dairy waxy and fatty nuances.

Taste threshold values

Taste characteristics at 1 to 10 ppm: sweet, fruity peach, milky fatty and waxy with a pulpy fruity mouthfeel.

Synthesis Reference(s)

Journal of the American Chemical Society, 108, p. 3745, 1986 DOI: 10.1021/ja00273a032
Organic Syntheses, Coll. Vol. 7, p. 400, 1990

Safety Profile

A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors

4-Dodecanolide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 272)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8754 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5242 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
JINING XINHE CHEMICAL CO., LTD
+8615318402391 sales@xinhepharma.com China 809 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
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18853181302 sale@chuangyingchem.com CHINA 5906 58
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Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from 4-Dodecanolide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Dodecanolide pictures 2026-01-16 4-Dodecanolide
2305-05-7
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-Dodecanolide pictures 2026-01-05 4-Dodecanolide
2305-05-7
US $10.00 / KG 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
4-Dodecanolide pictures 2025-05-26 4-Dodecanolide
2305-05-7
US $10.00 / KG 1KG 99.% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
  • 4-Dodecanolide pictures
  • 4-Dodecanolide
    2305-05-7
  • US $0.00 / KG
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • 4-Dodecanolide pictures
  • 4-Dodecanolide
    2305-05-7
  • US $10.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • 4-Dodecanolide pictures
  • 4-Dodecanolide
    2305-05-7
  • US $10.00 / KG
  • 99.%
  • Hebei Chuanghai Biotechnology Co,.LTD
(±)-γ-octyl-γ-butyrolactone DIHYDRO-5-OCTYL-2-FURANONE (Z)-4-HYDROXY-6-DODECENOICACIDLACTONE Dihydro-5-octylfuran-2(3H)-on DODECALACTON-GAMMA Natural gamma dodecalactone 5-Octyldihydrofuran-2(3H)-one GAMMA-DODECALACTONE, NATURAL (±)-γ-Octyl-γ-butyrolactone, (±)-Dihydro-5-octyl-2(3H)-furanone (±)-γ-Octyl-γ-butyrolactone, (±)-4-Dodecanolide, (±)-Dihydro-5-octyl-2(3H)-furanone 4,5-Dihydro-5-octyl-2(3H)-furanone 4-Hydroxylauric acid lactone 5-Octyl-4,5-dihydrofuran-2(3H)-one γ-Dodecanolide γ-Dodecalactone >= 99.0%, Natural, FCC DODECALACTONE, gamma(RG) (±)-4-Dodecanolide,(±)-γ-Octyl-γ-butyrolactone, (±)-Dihydro-5-octyl-2(3H)-furanone γ-Dodecalactone,Natural gamma-Dodecalactone gamma-Laurolactone γ-Dodecalactone,(±)-γ-Octyl-γ-butyrolactone, (±)-4-Dodecanolide, (±)-Dihydro-5-octyl-2(3H)-furanone dihydro-5-octylfuran-2(3H)-one (+/-)-4-DODECANOLIDE, STANDARD FOR GC GAMMA-DODECALACTONE 97+% FCC g-Dodecanolactone 5-Octyldihydro-2(3H)-furanone dihydro-5-octyl-2(3h)-furanon Dodecanoic acid, 4-hydroxy-, gamma-lactone Dodecanolide-1,4 gamma-n-Octyl-gamma-n-butyrolactone gamma-DodecalacetoneFCC Dihydro-5-octyl-1[3H]-furanone DODECANYL-LACTONE DODECALACTONE, GAMMA- (+/-)-DIHYDRO-5-OCTYL-2(3H)-FURANONE FEMA 2400 GAMMA-LAUROLACTONE (+/-)-GAMMA-OCTYL-GAMMA-BUTYROLACTONE GAMMA-DODECANOLACTONE G-DODECALACTONE 5-OCTYL-BUTYROLACTONE (+/-)-4-DODECANOLIDE 4-DODECANOLIDE 2-(3H)-Furanone, 5-octyldihydro- 2(3H)-Furanone, dihydro-5-octyl- 4-Hydroxydodecanoic acid lactone 4-Hydroxydodecanoic acid, gamma-lactone 5-octyloxolan-2-one 5-octyl-2-oxolanone gamma-DODECALACTONE FCC γ-Dodecanolactone> 4-Dodecanolide USP/EP/BP γ-Dodecanolactone γ-dodecalactone,4-dodecanolide,dihydro-5-octyl-2(3H)-furanone dodecalactone GAMMA-DODECALACTONE γ-Dodecalactone γ-Dodecalactone γ-Dodecanolactone, CAS 2305-05-7