4-Dodecanolide
- CAS No.
- 2305-05-7
- Chemical Name:
- 4-Dodecanolide
- Synonyms
- GAMMA-DODECALACTONE;γ-Dodecalactone;dodecalactone;γ-dodecalactone,4-dodecanolide,dihydro-5-octyl-2(3H)-furanone;FEMA 2400;γ-Dodecanolide;4-DODECANOLIDE;G-DODECALACTONE;γ-Dodecalactone;Dodecanolide-1,4
- CBNumber:
- CB3427330
- Molecular Formula:
- C12H22O2
- Molecular Weight:
- 198.3
- MDL Number:
- MFCD00036499
- MOL File:
- 2305-05-7.mol
Melting point | 17-18 °C(lit.) |
---|---|
Boiling point | 130-132 °C1.5 mm Hg(lit.) |
Density | 0.936 g/mL at 25 °C(lit.) |
vapor pressure | 7.3hPa at 20℃ |
refractive index |
n |
FEMA | 2400 | GAMMA-DODECALACTONE |
Flash point | >230 °F |
storage temp. | Refrigerator, under inert atmosphere |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
form | Oil |
color | Colourless |
Specific Gravity | 0.94 |
Odor | at 100.00 %. fatty peach sweet metallic fruity |
Odor Type | fruity |
biological source | synthetic |
Water Solubility | 60mg/L at 20℃ |
JECFA Number | 235 |
BRN | 126680 |
InChIKey | WGPCZPLRVAWXPW-UHFFFAOYSA-N |
LogP | 2.7 at 20℃ |
CAS DataBase Reference | 2305-05-7(CAS DataBase Reference) |
Substances Added to Food (formerly EAFUS) | GAMMA-DODECALACTONE |
EWG's Food Scores | 1 |
FDA UNII | YX9N4581LU |
NIST Chemistry Reference | «GAMMA» dodecalactone(2305-05-7) |
EPA Substance Registry System | 2(3H)-Furanone, dihydro-5-octyl- (2305-05-7) |
UNSPSC Code | 12164502 |
NACRES | NA.21 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | LU3600000 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29322090 | |||||||||
Toxicity | skn-rbt 500 mg/24H MOD FCTXAV 14,751,76 | |||||||||
NFPA 704 |
|
4-Dodecanolide price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | W240015 | γ-Dodecalactone natural, ≥98%, FG | 2305-05-7 | 100g | $210 | 2024-03-01 | Buy |
Sigma-Aldrich | W240015 | γ-Dodecalactone natural, ≥98%, FG | 2305-05-7 | 1kg | $1120 | 2024-03-01 | Buy |
Sigma-Aldrich | W240001 | γ-Dodecalactone ≥97%, FCC, FG | 2305-05-7 | sample-k | $54.6 | 2024-03-01 | Buy |
Sigma-Aldrich | W240001 | γ-Dodecalactone ≥97%, FCC, FG | 2305-05-7 | 100g | $79.8 | 2024-03-01 | Buy |
Sigma-Aldrich | W240001 | γ-Dodecalactone ≥97%, FCC, FG | 2305-05-7 | 1kg | $148 | 2024-03-01 | Buy |
4-Dodecanolide Chemical Properties,Uses,Production
Chemical Properties
γ-Dodecalactone has a fatty, peachy, somewhat musky odor and buttery, peach-like flavor
Occurrence
Reported found in apricot, cooked pork, milk products, peach, bilberry, guava fruit, papaya, pineapple, fresh blackberry, strawberry, celery leaves and stalks, celery root, blue cheeses, cheddar cheese, Swiss cheese, meats, beer, rum, mushrooms, plum brandy, quince, chervil, naranjilla fruit and other natural sources
Uses
4-Dodecanolide was one of the organic compounds from meat charbroiling operations studied. Finds some use in perfume compositions for fatty-fruity topnotes and long tenacity, e.g., in heavy floral fragrances. It is also used in combination with newer synthetic musks to produce exceptional tenacity and lasting sweetness in powdery and floral types. Used in flavour compositions, mainly in Butter, Butterscotch, Coconut, Tutti-frutti, Maple, Nut, Peach, Pineapple, etc.
Definition
ChEBI: Xi-Dihydro-5-octyl-2(3H)-furanone is a gamma-lactone.
Preparation
From 1-dodecen-12-oic acid with H2SO4 at 90°C; from 4-hydroxydodecanoic acid by lactonization; also from methylacrylate and octanol
Aroma threshold values
Detection: 7 ppb; aroma characteristics at 1.0%; sweet, creamy, fruity peach and apricot, lactonic, with dairy waxy and fatty nuances.
Taste threshold values
Taste characteristics at 1 to 10 ppm: sweet, fruity peach, milky fatty and waxy with a pulpy fruity mouthfeel.
Synthesis Reference(s)
Journal of the American Chemical Society, 108, p. 3745, 1986 DOI: 10.1021/ja00273a032
Organic Syntheses, Coll. Vol. 7, p. 400, 1990
Safety Profile
A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors
4-Dodecanolide Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co., Ltd | +86-15531157085 +86-15531157085 | abby@chuanghaibio.com | China | 8805 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12824 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5878 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 896 | 58 |
JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 809 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19840 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
View Lastest Price from 4-Dodecanolide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-03-17 | 4-Dodecanolide
2305-05-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
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2025-03-17 | 4-Dodecanolide
2305-05-7
|
US $99.00-35.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
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2025-03-13 | 4-Dodecanolide
2305-05-7
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- 4-Dodecanolide
2305-05-7
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 4-Dodecanolide
2305-05-7
- US $99.00-35.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- 4-Dodecanolide
2305-05-7
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
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