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Afurolol

Afurolol Structure
Afurolol structure
CAS No.
65776-67-2
Chemical Name:
Afurolol
Synonyms
Afurolol;Afurololum;7-[3-(tert-Butylamino)-2-hydroxypropoxy]isobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 7-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-
CBNumber:
CB41116269
Molecular Formula:
C15H21NO4
Molecular Weight:
279.33154
MDL Number:
MFCD00864583
MOL File:
65776-67-2.mol
Last updated:2022-12-21 16:56:50
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Afurolol Properties

FDA UNII WQ1WRV49R9

Afurolol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0016567 AFUROLOL 95.00% 65776-67-2 5MG $504.94 2021-12-16 Buy
Product number Packaging Price Buy
API0016567 5MG $504.94 Buy

Afurolol Chemical Properties,Uses,Production

Originator

Afurolol ,ZYF Pharm Chemical

Manufacturing Process

A mixture of 18.0 g (0.12 mole) 7-hydroxyphthalide, 180.0 g of 1-chloro-2,3- epoxypropane (2 moles) and 0.5 ml of piperidine is heated at 100°C for about 5 h and then the unreacted 1-chloro-2,3-epoxypropane is distilled off in vacuum to yield 12.0 g (48%) of 7-(2,3-epoxypropoxy)phthalide, melting point 88°-90°C, (crystallized successively from methanol and ethyl acetate).
The 7-(2,3-epoxypropoxy)phthalide is dissolved in methanol and t-butylamine are added to the solution at about 20°C. The solution is allowed to stand overnight and, the mixture is evaporated in vacuum and the residue is dried to give 7-(2-hydroxy-3-t-butylamino-propoxy)phthalide.

Therapeutic Function

Beta-adrenergic blocker

Afurolol Preparation Products And Raw materials

Raw materials

1-CHLORO-2,5-DIMETHYL-4-NITROBENZENE2-CHLORO-5-NITRO-P-XYLENE tert-Butylamine 7-hydroxyphthalide Epichlorohydrin

Preparation Products

Afurolol Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
TargetMol Chemicals Inc. 58

65776-67-2(Afurolol)Related Search:

2-(2-HYDROXY-ETHOXY)-BENZOIC ACID toliprolol Afurolol 2-(2-HYDROXY-ETHOXY)-BENZOIC ACID METHYL ESTER Xibenolol
2-Propoxybenzoic acid AKOS BC-1937

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Afurolol 7-[3-(tert-Butylamino)-2-hydroxypropoxy]isobenzofuran-1(3H)-one 1(3H)-Isobenzofuranone, 7-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]- Afurololum 65776-67-2