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Loperamide

Loperamide structure

CAS No.: 106900-12-3

Chemical Name:: Loperamide

Synonyms: R 58425;loperamide oxide;LoperaMide-d6 N-Oxide;Loperamide EP Impurity F;trans-Loperamide N-Oxide;Loperamide impurity-F(EP);Loperamide EP Impurity F HCl;Loperamide oxide monohydrate CRS;Loperamide USP Related Compound F;Loperamide Hydrochloride Impurity F

CBNumber:: CB41179066

Molecular Formula:: C29H33ClN2O3

Molecular Weight:: 493.04

MDL Number:: MFCD00870596

MOL File:: 106900-12-3.mol

MSDS File:: SDS

Last updated:2023-05-15 10:43:44

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Loperamide Properties

solubility	Practically insoluble in water, freely soluble in alcohol and in methylene chloride.
pka	12.94±0.20(Predicted)
Stability	Hygroscopic
FDA UNII	NG66S4H2RL
ATC code	A07DA05

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P264-P270-P301+P310-P405-P501
RIDADR	UN 2811 6.1 / PGIII
RTECS	TM4960200
HS Code	2933399090

Loperamide price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0000341	Loperamide oxide monohydrate European Pharmacopoeia (EP) Reference Standard	106900-12-3	y0000341	$220	2024-03-01	Buy
Sigma-Aldrich	PHR2916	Loperamide Related Compound F pharmaceutical secondary standard, certified reference material	106900-12-3	50MG	$575	2024-03-01	Buy
Sigma-Aldrich	BP636	Loperamide N-oxide British Pharmacopoeia (BP) Reference Standard	106900-12-3	25MG	$273	2024-03-01	Buy
Sigma-Aldrich	1370065	Loperamide oxide monohydrate	106900-12-3	25mg	$1490	2024-03-01	Buy
TRC	L469460	trans-LoperamideN-Oxide	106900-12-3	250mg	$1040	2021-12-16	Buy

Product number	Packaging	Price	Buy
Y0000341	y0000341	$220	Buy
PHR2916	50MG	$575	Buy
BP636	25MG	$273	Buy
1370065	25mg	$1490	Buy
L469460	250mg	$1040	Buy

Loperamide Chemical Properties,Uses,Production

Chemical Properties

White or almost white powder, slightly hygroscopic.

Uses

Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

Uses

Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

Definition

ChEBI: Loperamide oxide is a diarylmethane.

Loperamide Preparation Products And Raw materials

Raw materials

Preparation Products

Loperamide Suppliers

Global( 49)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
ChemStrong Scientific Co.,Ltd	0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shenzhen SUNGENING Bio-Medical Co., Ltd.	0755-28967200 13631290199	wxf@sungening.com	China	9506	60

Supplier	Advantage
Standardpharm Co. Ltd.	58
TargetMol Chemicals Inc.	58
AFINE CHEMICALS LIMITED	58
sgtlifesciences pvt ltd	58
J & K SCIENTIFIC LTD.	76
Chemsky (shanghai) International Co.,Ltd	60
BOC Sciences	65
ChemStrong Scientific Co.,Ltd	56
BOC Sciences	65
Shenzhen SUNGENING Bio-Medical Co., Ltd.	60

106900-12-3(Loperamide)Related Search:

1-(4-CHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL (R)-1-(4-CHLOROPHENYL)-1-PROPANOL fenpipramide 4-(4-CHLOROPHENYL)PIPERIDINE Alverine

Trimethylamine N-oxide 4-(4-Chlorophenyl)piperidin-4-ol (Diphenyl-3,3 propyl)-1 phenyl-4 piperidine chlorhydrate [French] Loperamide Trimethylamine N-oxide dihydrate

2,2-DIPHENYLPROPYLAMINE HYDROCHLORIDE TRIETHYLAMINE N-OXIDE DIPHENAMID DESMETHYL LOPERAMIDE Loperamide

1of3

loperamide oxide R 58425 trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide LoperaMide-d6 N-Oxide Loperamide EP Impurity F Loperamide impurity-F(EP) trans-Loperamide N-Oxide Loperamide Impurity 6（Loperamide EP Impurity F） Loperamide oxide monohydrate CRS 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, 1-oxide, trans- Loperamide EP Impurity F/ Loperamide Related Compound F (Loperamide N-Oxide) 4-[TRANS-4-(4-CHLOROPHENYL)-4-HYDROXY-1- OXIDOPIPERIDIN-1-YL]-N,N-DIMETHYL-2,2- DIPHENYLBUTANAMIDE HYDROCHLORIDE Loperamide N-oxideQ: What is Loperamide N-oxide Q: What is the CAS Number of Loperamide N-oxide Q: What is the storage condition of Loperamide N-oxide Q: What are the applications of Loperamide N-oxide Loperamide Related Compound F ((1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbu (1370065) Loperamide Hydrochloride Impurity F Loperamide EP Impurity F HCl Loperamide USP Related Compound F Loperamide Hydrochloride EP Impurity F Loperamide EP Impurity F (Loperamide USP Related Compound F, trans-Loperamide N-Oxide) 106900-12-3 C29H27D6ClN2O3 Amines Drug Analogues Heterocycles Intermediates & Fine Chemicals Isotope Labelled Compounds Metabolites & Impurities Pharmaceuticals