ChemicalBook >> CAS DataBase List >>Atorvastatin lactone

Atorvastatin lactone

CAS No.
125995-03-1
Chemical Name:
Atorvastatin lactone
Synonyms
5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide;PD-130694;ATORVASTATIN LACTONE;Atorvastatin USP RC H;Atorvastatin d-Lactone;Atorvastatin calcium-6;Atorvastatin Impurity H;LACTONE IMPURITY(IMP-H);(RS) Atorvastatin Lactone;Atorvastatin EP IMpurity H
CBNumber:
CB4313438
Molecular Formula:
C33H33FN2O4
Molecular Weight:
540.62
MDL Number:
MFCD00899262
MOL File:
125995-03-1.mol
Last updated:2023-07-06 13:51:49

Atorvastatin lactone Properties

Melting point 103-106°C
alpha D +26.05° (c = 1 in chloroform)
Boiling point 674.8±55.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 13.39±0.40(Predicted)
color White to Light Yellow
Merck 14,864
FDA UNII 7876IL7J2N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933.99.7500
NFPA 704
0
2 0

Atorvastatin lactone price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1044582 Atorvastatin Related Compound H United States Pharmacopeia (USP) Reference Standard 125995-03-1 20MG $1380 2024-03-01 Buy
TCI Chemical A3114 Atorvastatin Lactone >95.0%(HPLC) 125995-03-1 25mg $122 2024-03-01 Buy
TCI Chemical A3114 Atorvastatin Lactone >95.0%(HPLC) 125995-03-1 100mg $362 2024-03-01 Buy
Cayman Chemical 20951 Atorvastatin lactone ≥95% 125995-03-1 1mg $32 2024-03-01 Buy
Cayman Chemical 20951 Atorvastatin lactone ≥95% 125995-03-1 5mg $116 2024-03-01 Buy
Product number Packaging Price Buy
1044582 20MG $1380 Buy
A3114 25mg $122 Buy
A3114 100mg $362 Buy
20951 1mg $32 Buy
20951 5mg $116 Buy

Atorvastatin lactone Chemical Properties,Uses,Production

Chemical Properties

Slightly Yellow Solid

Uses

Atorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.

Uses

Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation

Atorvastatin lactone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 191)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410 sales@ichemie.com China 985 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58

View Lastest Price from Atorvastatin lactone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Atorvastatin Impurity H(EP) pictures 2024-04-10 Atorvastatin Impurity H(EP)
125995-03-1
US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
Atorvastatin Impurity E Intermediate pictures 2024-04-10 Atorvastatin Impurity E Intermediate
US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide pictures 2023-11-01 5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
125995-03-1
US $0.00-0.00 / KG 1KG 99% 500 Hangzhou ICH Biofarm Co., Ltd
Atorvastatin d-Lactone (4R,6R)-6-{2-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-4-hydroxytetrahydro-2H-pyran-2-one (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid 1,5-lactone 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide Atorvastatin EPIMp H (USP RCH) Atorvastatin EP IMpurity H Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide) Diepoxide Atorvastatin Lactone Diepoxide Atorvastatin Calcium Impurity D Atorvastatin Impurity H (RS) Atorvastatin Lactone ATORVASTATIN LACTONE Atorvastatin calcium-6 5-(4-fluorophenyl)-1-(2-((2R,4R) Atorvastatin Calcium Hydrate impurity H Atorvastatin EP Impurity H (Atorvastatin Lactone) 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide (4R,6R)-6-[2-[2-(4-Fluorophenyl)-5- Atorvastatin Lactone (Atorvastatin EP Impurity H) PD-130694 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]- 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide Atorvastatin lactone ( imp H) USP Atorvastatin Related Compound H Atorvastatin EP Impurity H/ Atorvastatin Related Compound H (Atorvastatin Lactone) Atorvastatin D5 LactoneQ: What is Atorvastatin D5 Lactone Q: What is the CAS Number of Atorvastatin D5 Lactone Q: What is the storage condition of Atorvastatin D5 Lactone Q: What are the applications of Atorvastatin D5 Lactone Atorvastatin LactoneQ: What is Atorvastatin Lactone Q: What is the CAS Number of Atorvastatin Lactone Q: What is the storage condition of Atorvastatin Lactone Q: What are the applications of Atorvastatin Lactone Atorvastatin Related Compound H (1044582)Q: What is Atorvastatin Related Compound H (1044582) Q: What is the CAS Number of Atorvastatin Related Compound H (1044582) Atorvastatin lactone (EP impurity H) (4R,6R)-6-[2-[2-(4-flfluorophenyl)-5-(1-methylethyl)-3- phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl]-4- hydroxytetrahydro-2H-pyran-2-one Atorvastatin Impurity H(EP) Atorvastatin USP RC H Atorvastatin EP Impurity H (USP RC H)Ator. Lacton Atorvastatin impurity 9/Atorvastatin EP Impurity H/Atorvastatin Lactone/5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide AtorvastatinEPImpurityH-d5 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide Atorvastatin USP Related Compound H Atorvastatin Calcium Trihydrate EP Impurity H LACTONE IMPURITY(IMP-H) Atorvastatin Calcium Trihydrate Impurity H Atorvastatin calcium impurity H Atorvastatin EP Impurity H (Atorvastatin USP Related Compound H, Atorvastatin Lactone) 125995-03-1 C33H33FN2O4 Inhibitors Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals