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| | Atorvastatin lactone Basic information |
| Product Name: | Atorvastatin lactone | | Synonyms: | Atorvastatin d-Lactone;(4R,6R)-6-{2-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-4-hydroxytetrahydro-2H-pyran-2-one;(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid 1,5-lactone;1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide;Atorvastatin EPIMp H (USP RCH);Atorvastatin EP IMpurity H;Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide);Diepoxide Atorvastatin Lactone Diepoxide | | CAS: | 125995-03-1 | | MF: | C33H33FN2O4 | | MW: | 540.62 | | EINECS: | | | Product Categories: | Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 125995-03-1.mol |  |
| | Atorvastatin lactone Chemical Properties |
| Melting point | 103-106°C | | alpha | D +26.05° (c = 1 in chloroform) | | Boiling point | 674.8±55.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.39±0.40(Predicted) | | color | White to Light Yellow | | Merck | 14,864 |
| | Atorvastatin lactone Usage And Synthesis |
| Chemical Properties | Slightly Yellow Solid | | Uses | Atorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation. | | Uses | Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation |
| | Atorvastatin lactone Preparation Products And Raw materials |
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