1-METHYL-1H-INDOLE-4-CARBALDEHYDE
- CAS No.
- 133994-99-7
- Chemical Name:
- 1-METHYL-1H-INDOLE-4-CARBALDEHYDE
- Synonyms
- 1-METHYL-1H-INDOLE-4-CARBALDEHYDE;1-methyl-1H-indol-4-carboxaldehyde;1H-Indole-4-carboxaldehyde, 1-methyl-;1H-Indole-4-carboxaldehyde, 1-methyl- (9CI);1-methyl-1H-indole-4-carbaldehyde(SALTDATA: FREE)
- CBNumber:
- CB4589545
- Molecular Formula:
- C10H9NO
- Molecular Weight:
- 159.18
- MDL Number:
- MFCD08690261
- MOL File:
- 133994-99-7.mol
| Product description | Number | Pack Size | Price |
| 1-Methyl-1H-indole-4-carbaldehyde | M221745 | 50mg | $90 |
| 1-Methyl-1H-indole-4-carbaldehyde | M221745 | 100mg | $130 |
| 1-Methyl-1H-indole-4-carbaldehyde | Z4100 | 250mg | $185 |
| 1-Methyl-1H-indole-4-carbaldehyde | 036759 | 500mg | $252 |
| 1-METHYL-1H-INDOLE-4-CARBALDEHYDE 95.00% | CHM0018145 | 0.5G | $726 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H332-H312-H335-H319-H315 | |||||||||
| Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| HazardClass | IRRITANT | |||||||||
| NFPA 704 |
|
1-METHYL-1H-INDOLE-4-CARBALDEHYDE price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M221745 | 1-Methyl-1H-indole-4-carbaldehyde | 133994-99-7 | 50mg | $90 | 2021-12-16 | Buy |
| TRC | M221745 | 1-Methyl-1H-indole-4-carbaldehyde | 133994-99-7 | 100mg | $130 | 2021-12-16 | Buy |
| AK Scientific | Z4100 | 1-Methyl-1H-indole-4-carbaldehyde | 133994-99-7 | 250mg | $185 | 2021-12-16 | Buy |
| Matrix Scientific | 036759 | 1-Methyl-1H-indole-4-carbaldehyde | 133994-99-7 | 500mg | $252 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0018145 | 1-METHYL-1H-INDOLE-4-CARBALDEHYDE 95.00% | 133994-99-7 | 0.5G | $726 | 2021-12-16 | Buy |
1-METHYL-1H-INDOLE-4-CARBALDEHYDE Chemical Properties,Uses,Production
Synthesis
1074-86-8
74-88-4
133994-99-7
a) Synthesis of 1-methyl-1H-indole-4-carboxaldehyde: Sodium hydride (171 mg, 60% oil dispersion, 4.27 mmol) was added batchwise to an anhydrous N,N-dimethylformamide (DMF, 6.5 mL) solution of 1H-indole-4-carboxaldehyde (413 mg, 2.85 mmol) under argon protection. The reaction mixture was stirred at room temperature for 40 min. Subsequently, iodomethane (0.36 mL, 5.78 mmol) was slowly added dropwise and the reaction continued to be stirred at room temperature for 12 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (25 mL) and extracted with ethyl acetate (3 x 25 mL). The organic phases were combined, washed sequentially with water (20 mL) and saturated saline (20 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give a yellow oily crude product. Purification by silica gel column chromatography (eluent: dichloromethane) gave 1-methyl-1H-indole-4-carboxaldehyde (452 mg, 99% yield) as yellow oil.1H NMR (400 MHz, DMSO-d6) δ 10.20 (s, 1H), 7.84 (d, J = 8.0 Hz, 1H), 7.68 (d, J = 7.2 Hz, 1H), 7.58 (d, J = 7.2 Hz, 1H). 7.58 (d, J = 2.8 Hz, 1H), 7.38-7.34 (m, 1H), 7.08 (d, J = 3.2 Hz, 1H), 3.87 (s, 3H).
References
[1] Patent: WO2007/53131, 2007, A2. Location in patent: Page/Page column 178
[2] European Journal of Medicinal Chemistry, 2017, vol. 134, p. 13 - 23
[3] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 7, p. 2060 - 2079
[4] Journal of Organometallic Chemistry, 2011, vol. 696, # 5, p. 1072 - 1083
[5] Patent: WO2012/47702, 2012, A1. Location in patent: Page/Page column 32
1-METHYL-1H-INDOLE-4-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5998 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35896 | 56 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 4021 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17770 | 75 |
View Lastest Price from 1-METHYL-1H-INDOLE-4-CARBALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-02-02 | 1-METHYL-1H-INDOLE-4-CARBALDEHYDE
133994-99-7
|
US $1.00 / g | 1g | 99% | 200g | Career Henan Chemical Co |
-
- 1-METHYL-1H-INDOLE-4-CARBALDEHYDE
133994-99-7
- US $1.00 / g
- 99%
- Career Henan Chemical Co
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