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anhydrotetrodotoxin
- CAS No.
- 13072-89-4
- Chemical Name:
- anhydrotetrodotoxin
- Synonyms
- 9-anhydro-TTX;4,9-Anhydro-TTX;anhydrotetrodotoxin;4,9-Anhydrotetrodotoxin;4,9-Dideoxy-4β,9β-epoxytetrodotoxin;(8S)-4,9-Dideoxy-4β,9β-epoxytetrodotoxin;4,9Anhydrotetrodotoxin,4,9 Anhydrotetrodotoxin;(4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-2-Amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-6,10-epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol;6,10-Epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol, 2-amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-, (4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-
- CBNumber:
- CB51328746
- Molecular Formula:
- C11H15N3O7
- Molecular Weight:
- 301.25
- MDL Number:
- MFCD01682463
- MOL File:
- 13072-89-4.mol
Last updated:2023-06-30 15:45:59
storage temp. | -20° |
---|---|
solubility | Soluble in Ethanol (up to 10 mg/ml). |
form | A solid or film |
color | Colorless |
Water Solubility | Soluble to 1 mg/ml in water |
Stability | Stable for 2 years from date of purchase as supplied. Protect from exposure to light or moisture. Solutions are not stable. Solutions must be prepared fresh and used within 1 working day. |
anhydrotetrodotoxin price More Price(2)
anhydrotetrodotoxin Chemical Properties,Uses,Production
Description
4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). It demonstrates IC50 values of 1.3, 0.34, 0.99, 78.5, 1.3, and >30 μM for Nav1.2, Nav1.3, Nav1.4, Nav1.5, Nav1.7, and Nav1.8, respectively.
storage
Store at -20°C
References
1) Rosker?et al. (2007),?The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel; Am.J.Physiol.Cell Physiol.,?293?C783. 2) Denomme?et al.?(2020),??The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Nav1.1 in addition to Nav1.6;?Neurosci. Lett.?724?134853
anhydrotetrodotoxin Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
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Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 | 13119157289@163.com | China | 2971 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
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Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
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Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | 18049165724 13186333400 | cuichengbio@163.com | China | 2605 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
13072-89-4(anhydrotetrodotoxin)Related Search:
anhydrotetrodotoxin
(8S)-4,9-Dideoxy-4β,9β-epoxytetrodotoxin
4,9-Anhydrotetrodotoxin
4,9-Dideoxy-4β,9β-epoxytetrodotoxin
(4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-2-Amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-6,10-epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol
6,10-Epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol, 2-amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-, (4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-
9-anhydro-TTX
4,9Anhydrotetrodotoxin,4,9 Anhydrotetrodotoxin
4,9-Anhydro-TTX
13072-89-4