ChemicalBook >> CAS DataBase List >>1-(2-Chlorophenyl)piperazine hydrochloride
1-(2-Chlorophenyl)piperazine hydrochloride
- CAS No.
- 41202-32-8
- Chemical Name:
- 1-(2-Chlorophenyl)piperazine hydrochloride
- Synonyms
- TIMTEC-BB SBB003263;LABOTEST-BB LT00454957;LABOTEST-BB LT00159499;Trazodone Impurity 9 HCl;Trazodone Impurity 7 HCl;Trazodone Impurity 33 HCl;2-CHLOROPHENYL PIPERAZINE HCL;1-(2-CHLOROPHENYL)PIPERAZINE HCL;2-CHLOROPHENYLPIPERAZINE HYDROCHLORIDE;1-(2-chlorophenyl)piperazinium chloride
- CBNumber:
- CB5196290
- Molecular Formula:
- C10H14Cl2N2
- Molecular Weight:
- 233.14
- MDL Number:
- MFCD00012761
- MOL File:
- 41202-32-8.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:21:21
| Product description | Number | Pack Size | Price |
| 1-(2-Chlorophenyl)piperazine monohydrochloride 95% | C67605 | 10g | $120 |
| 1-(2-Chlorophenyl)piperazine hydrochloride 95+% | 074236 | 5g | $10 |
| 1-(2-Chlorophenyl)piperazine hydrochloride 95+% | 074236 | 25g | $28 |
| 1-(2-Chlorophenyl)-piperazine hydrochloride | FC36602 | 10g | $60 |
| 1-(2-Chlorophenyl)piperazine hydrochloride 95+% | 074236 | 100g | $105 |
| More product size | |||
| Melting point | 160-163 °C (dec.)(lit.) |
|---|---|
| storage temp. | Store at room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White |
| Sensitive | Hygroscopic |
| BRN | 5652889 |
| InChI | 1S/C10H13ClN2.ClH/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13;/h1-4,12H,5-8H2;1H |
| InChIKey | GUTWDZXWTKMXPI-UHFFFAOYSA-N |
| SMILES | Cl[H].Clc1ccccc1N2CCNCC2 |
| CAS DataBase Reference | 41202-32-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
1-(2-Chlorophenyl)piperazine hydrochloride price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C67605 | 1-(2-Chlorophenyl)piperazine monohydrochloride 95% | 41202-32-8 | 10g | $120 | 2026-04-30 | Buy |
| Matrix Scientific | 074236 | 1-(2-Chlorophenyl)piperazine hydrochloride 95+% | 41202-32-8 | 5g | $10 | 2021-12-16 | Buy |
| Matrix Scientific | 074236 | 1-(2-Chlorophenyl)piperazine hydrochloride 95+% | 41202-32-8 | 25g | $28 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC36602 | 1-(2-Chlorophenyl)-piperazine hydrochloride | 41202-32-8 | 10g | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 074236 | 1-(2-Chlorophenyl)piperazine hydrochloride 95+% | 41202-32-8 | 100g | $105 | 2021-12-16 | Buy |
1-(2-Chlorophenyl)piperazine hydrochloride Chemical Properties,Uses,Production
Uses
1-(2-Chlorophenyl)piperazine Hydrochloride is a reactant used in the preparation of piperazinyl, phenylpiperidinyl, tetrahydropyridinyl, and tetrahydropyridoindolylbutylbenzindoles with 5-hydroxytryptamine receptor antagonist activity.
Synthesis
1104513-49-6
41202-32-8
To a stirred solution of tert-butyl 4-(2-chlorophenyl)piperazine-1-carboxylate (250 mg, 0.844 mmol) in 1,4-dioxane (2 mL) was added slowly and dropwise a 1,4-dioxane solution (0.9 mL, 3.60 mmol) in 4 N HCl at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 h (complete consumption of feedstock was confirmed by TLC monitoring). Upon completion of the reaction, the volatile solvent was removed under reduced pressure to give the crude product. The crude product was washed with ether (2 x 20 mL) and dried under high vacuum to yield 1-(2-chlorophenyl)piperazine hydrochloride (165 mg, 84% yield) as a white solid.
References
[1] Patent: WO2018/125961, 2018, A1. Location in patent: Page/Page column 45; 46
Synthesis of 1-(2-Chlorophenyl)piperazine hydrochloride from Bis(2-chloroethyl)amine hydrochloride and 2-Chloroaniline
1-(2-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials
Global( 160)Suppliers
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View Lastest Price from 1-(2-Chlorophenyl)piperazine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 1-(2-Chlorophenyl)piperazine hydrochloride
41202-32-8
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-02-26 | 1-(2-Chlorophenyl) piperazine
41202-32-8
|
US $0.00-0.00 / Kg | 1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
|
|
2020-02-26 | 1-(2-Chlorophenyl) piperazine
41202-32-8
|
US $0.00-0.00 / Kg | 1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 1-(2-Chlorophenyl)piperazine hydrochloride
41202-32-8
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(2-Chlorophenyl) piperazine
41202-32-8
- US $0.00-0.00 / Kg
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(2-Chlorophenyl) piperazine
41202-32-8
- US $0.00-0.00 / Kg
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
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TIMTEC-BB SBB003263
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1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 99%
1-(2-CHLOROPHENYL)PIPERAZINE HCL
2-CHLOROPHENYLPIPERAZINE HYDROCHLORIDE
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1-(2-Chlorophenyl)piperazine monohydrochloride monohydrate, 98%
1-(2-Chlorophenyl)piperazine monohydrochloride 95%
ortho-Chlorophenylpiperazine Hydrochloride (oCPP HCl)
Trazodone Impurity 33 HCl
Trazodone Impurity 9 HCl
Trazodone Impurity 7 HCl
ortho-Chlorophenylpiperazine Hydrochloride (oCPP HCl) 1.0 mg/ml in Methanol (as free base)
41202-32-8
C10H15Cl3N2
C10H14C12N2
AMINE
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