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U-74389G

CAS No.
153190-29-5
Chemical Name:
U-74389G
Synonyms
METHYLATED TIRILAZAD;U-74389G;U74389G,U 74389G;DESMETHYL TIRILAZAD;(Z)-2-BUTENEDIONATE;ABCSSKWSUJMJCP-WQDFMEOSSA-N;21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE;21-[4-(4,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL]-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE MALEATE;21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt;21-(4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIOATE
CBNumber:
CB5461091
Molecular Formula:
C41H54N6O6
Molecular Weight:
726.9
MDL Number:
MFCD01074991
MOL File:
153190-29-5.mol
Last updated:2023-05-18 11:31:17

U-74389G Properties

storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility ethanol: soluble20 mg/mL, clear, light yellow
form White solid.
color White
Sensitive Hygroscopic
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

WGK Germany  3

U-74389G price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich U5882 U-74389G 153190-29-5 100mg $285 2024-03-01 Buy
Alfa Aesar J67212 U-74389G 98% 153190-29-5 100mg $183 2021-12-16 Buy
Cayman Chemical 75860 U-74389G ≥99% 153190-29-5 50mg $72 2024-03-01 Buy
Cayman Chemical 75860 U-74389G ≥99% 153190-29-5 100mg $115 2024-03-01 Buy
Cayman Chemical 75860 U-74389G ≥99% 153190-29-5 250mg $266 2024-03-01 Buy
Product number Packaging Price Buy
U5882 100mg $285 Buy
J67212 100mg $183 Buy
75860 50mg $72 Buy
75860 100mg $115 Buy
75860 250mg $266 Buy

U-74389G Chemical Properties,Uses,Production

Description

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.

Uses

U-74389G is a potent inhibitor of superoxide-mediated lipid peroxidation.

References

1) Braughler et al. (1987) Novel 21-aminosteroids as potent inhibitors of iron-dependent lipid peroxidation; J. Biol. Chem., 262 10438 2) Campo et al. (1996) Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation; J. Pharmacol. Exp. Ther., 277 333 3) Perna et al. (1996) Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G; Pharmacol. Res., 34 25

U-74389G Preparation Products And Raw materials

Raw materials

Preparation Products

U-74389G Suppliers

Global( 58)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 3864 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Guangzhou Yunmen Biotechnology Co., Ltd 18902340307 18902340307 3356812514@qq.com China 9238 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
U-74389G (Z)-2-BUTENEDIONATE 21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE 21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIONATE 21-(4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIOATE 21-[4-(4,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL]-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE MALEATE DESMETHYL TIRILAZAD 21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt ABCSSKWSUJMJCP-WQDFMEOSSA-N METHYLATED TIRILAZAD (8S,10S,13S,14S,17S)-17-(2-(4-(2,6-Di(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)acetyl)-10,13-dimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one maleate U74389G,U 74389G 153190-29-5 C37H50N6O2C4H4O4