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5-Azacytosine

5-Azacytosine structure

CAS No.: 931-86-2

Chemical Name:: 5-Azacytosine

Synonyms: AZACYTOSINE;4-aMino-1,3,5-triazin-2-ol;4-amino-1,3,5-triazin-2(1h)-one;NSC 54006;NSC 51100;5-Azacytosin;5 zacytosine;5-AZACYTOSINE;5-Azacytosine,98%;5-Azacytosine API

CBNumber:: CB6465182

Molecular Formula:: C3H4N4O

Molecular Weight:: 112.09

MDL Number:: MFCD00006033

MOL File:: 931-86-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:59:17

Product description	Number	Pack Size	Price
Azacitidine Related Compound A certified reference material, pharmaceutical secondary standard	PHR3473	50MG	$704
5-Azacytosine	855049	5g	$90.1
Azacitidine Related Compound A United States Pharmacopeia (USP) Reference Standard	1045539	25mg	$1390
5-Azacytosine Hydrate >98.0%(T)	A1091	5g	$59
5-Azacytosine Hydrate >98.0%(T)	A1091	25g	$236
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5-Azacytosine Properties

Melting point	>300 °C (lit.)
Boiling point	209.98°C (rough estimate)
Density	1.86
refractive index	1.8010 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
pka	7.61±0.10(Predicted)
form	Solid
color	White to Off-White
BRN	116378
Major Application	pharmaceutical (small molecule)
InChI	InChI=1S/C3H4N4O/c4-2-5-1-6-3(8)7-2/h1H,(H3,4,5,6,7,8)
InChIKey	MFEFTTYGMZOIKO-UHFFFAOYSA-N
SMILES	N1C(N)=NC=NC1=O
CAS DataBase Reference	931-86-2(CAS DataBase Reference)
FDA UNII	C5UW4MS7VR
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

RTECS

XZ2854300

HS Code

29336990

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

5-Azacytosine price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR3473	Azacitidine Related Compound A certified reference material, pharmaceutical secondary standard	931-86-2	50MG	$704	2026-03-19	Buy
Sigma-Aldrich	855049	5-Azacytosine	931-86-2	5g	$90.1	2026-03-19	Buy
Sigma-Aldrich	1045539	Azacitidine Related Compound A United States Pharmacopeia (USP) Reference Standard	931-86-2	25mg	$1390	2026-03-19	Buy
TCI Chemical	A1091	5-Azacytosine Hydrate >98.0%(T)	931-86-2	5g	$59	2026-03-19	Buy
TCI Chemical	A1091	5-Azacytosine Hydrate >98.0%(T)	931-86-2	25g	$236	2026-03-19	Buy

Product number	Packaging	Price	Buy
PHR3473	50MG	$704	Buy
855049	5g	$90.1	Buy
1045539	25mg	$1390	Buy
A1091	5g	$59	Buy
A1091	25g	$236	Buy

5-Azacytosine Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Reactant for:

Enzymic synthesis of nucleoside analogs using immobilized 2′-deoxyribosyltransferase from Lactobacillus reuteri
Reactions with oxide radical ion

Potential antitumor and antiproliferative agent against human leukemia cells

Uses

5-Azacytosine can inhibits the growth of Escherichia coli and used as the most effective cytosine mimics for the design of novel antiviral and anti-tumor drug candidates.

Definition

ChEBI: A monoamino-1,3,5-triazine that is cytosine in which the aromatic CH at position 5 is replaced by a nitrogen.

Synthesis

64-18-6

127099-85-8

931-86-2

(1) Add 1.5Kg of anhydrous formic acid (99.5% purity), 2.5kg of dicyandiamide and 0.005Kg of p-toluenesulfonic acid catalyst to a 10L autoclave. Under the condition of sealing and stirring, the reaction system was slowly warmed up to 110°C and the reaction pressure was maintained. After the reaction was completed, the temperature was slowly cooled down to room temperature to obtain a white solid product. (2) The resulting white solid was transferred to a 50L glass reactor and 10L of dilute hydrochloric acid solution with a mass concentration of 5% was added. Heating was refluxed for 30 minutes until the solution was clarified. Subsequently, the mixture was filtered through a cartridge into a crystallizer. A 30% ammonia solution was added to the crystallizer and the pH was adjusted to 6. White crystals were precipitated. After centrifugation and drying in a hot air oven, 2.8-5 kg of 6-amino-1,3,5-triazin-2(1H)-one (85% yield as dicyandiamide) was finally obtained.

References

[1] Patent: CN105837524, 2016, A. Location in patent: Paragraph 0042; 0043; 0044; 0045; 0046; 0047; 0048-0079
[2] Chemische Berichte, 1954, vol. 87, p. 19,23
[3] Archiv der Pharmazie (Weinheim, Germany), 1955, vol. 288, p. 139
[4] Patent: CN104402836, 2016, B. Location in patent: Paragraph 0025; 0026; 0027; 0028

5-Azacytosine synthesis

Synthesis of 5-Azacytosine from Ethanimidamide, N-cyano- and Ethyl formate

5-Azacytosine Preparation Products And Raw materials

Raw materials

Formic acid Guanidine, N''-cyano- (9CI) Hydrochloric acid

Preparation Products

5-Azacytosine Suppliers

Global( 611)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Kangcang new material Technology Co., LTD	+8615713292910	Nancy@kangcang.com.cn	China	341	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850	info@fortunachem.com	China	5975	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Wuhan Quanjinci New Material Co.,Ltd.	+86-15271838296; +8615271838296	kyra@quanjinci.com	China	1512	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21591	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60

Supplier	Advantage
Hebei Kangcang new material Technology Co., LTD	58
Wuhan Fortuna Chemical Co., Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Wuhan Quanjinci New Material Co.,Ltd.	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60

View Lastest Price from 5-Azacytosine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-28	5-azacytosine 931-86-2	US $99.00 / Kg	1Kg	98%	20Ton	Xinxiang Aurora Biotechnology Co.,Ltd.
2026-04-28	5-Azacytosine 931-86-2	US $0.00-0.00 / kg	1kg	98%min HPLC	500 KG	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-27	5-Azacytosine 931-86-2	US $0.00 / kg	1kg	99%min	20tons	HANGZHOU HAILAN CHEMICAL CO.,LTD.

5-azacytosine
931-86-2
US $99.00 / Kg
98%
Xinxiang Aurora Biotechnology Co.,Ltd.

5-Azacytosine
931-86-2
US $0.00-0.00 / kg
98%min HPLC
WUHAN FORTUNA CHEMICAL CO., LTD

5-Azacytosine
931-86-2
US $0.00 / kg
99%min
HANGZHOU HAILAN CHEMICAL CO.,LTD.

5-Azacytosine Spectrum

5-Azacytosine(931-86-2)MS 5-Azacytosine(931-86-2)¹HNMR 5-Azacytosine(931-86-2)IR1 5-Azacytosine(931-86-2)IR2 5-Azacytosine(931-86-2)Raman

931-86-2(5-Azacytosine)Related Search:

4-Aminoacetophenone ANILAZINE 5-METHYLCYTOSINE Toltrazuril beta-Methyl vinyl phosphate (MAP)

CHLOROPHOSPHONAZO III 3-Aminoacetophenone Cytosine Metribuzin Fluorocytosine

Betaine 2-Aminoacetophenone Buprofezin 1,3,5-Triazine Glycine

Aminoethoxyvinyl glycine hydrochloride 5-Azacytidine / 5-Azacytosine 5-Aza-2'-deoxycytidine

1of4

5-triazin-2(1h)-one,4-amino-3 2-Amino-4-hydroxy-1,3,5-triazine 2-AMINO-4-HYDROXY-S-TRIAZINE 4-AMINO-1,3,5-TRIAZIN-2-ONE 4-AMINO-1,3,5-TRIAZINE-2[1H]-ONE 4-AMINO-S-TRIAZIN-2(1H)-ONE 5-AZACYTOSINE 5-Azacytosine,98% 4-amino-s-triazin-2-o NSC 51100 NSC 54006 5-Azacytosine API 2-Amino-4-hydroxy-1,3,5-triazine 4-Amino-1,3,5-triazin-2(1H)-one 2-AMino-4-hydroxy-1,3,5-triazin AZACYTOSINE, 5-(RG) 4-aMino-1,2-dihydro-1,3,5-triazin-2-one 4-Aino-[1,3,5]triazin-2-ol 5-aza-cytosine, 4-aMino-1,2-dihydro-1,3,5-triazin-2-one, 5-azacytosine 5-Azacytosine 5-Azacytosine, 98+% 5GR 1,3,5-Triazin-2(1H)-one, 4-aMino- (9CI) s-Triazin-2(1H)-one, 4-aMino- (8CI) Azacitidine Related CoMpound A Azacitidine Related Compound A (15 mg) (4-Amino-1,3,5-triazin-2(1H)-one) Azacitidine Related Compound C (15 mg) (1-beta-D-Ribofuranosyl-3-guanylurea picrate) 5-AZACYTOSINE (DRY WT.), MAY CONT. UP TO CA 7% WATER 6-Amino-1H-[1,3,5]triazin-2-one 4-Amino-1H-[1,3,5]triazin-2-one 5-Azacytosine, 98% (dry wt.), may cont. up to ca 7% water 5-Azacytosine Hydrate 2-Hydroxy-4-aminotriazine 4-Amino-2-hydroxy-1,3,5-triazine 4-Amino-2-triazin-2(1H)-one 4-Amino-3H-1,3,5-triazin-2-one 4-Amino-s-triazin-2-ol 4(1H)-Imino-1,3,5-triazine-2-ol 4(3H)-Imino-1,3,5-triazine-2(1H)-one 4(5H)-Imino-1,3,5-triazine-2(3H)-one 4-Amino-1,3,5-triazine-2(3H)-one 4-Amino-1,3,5-triazine-2-ol 4-amino-s-triazin-2(1h)-on 5-Azacytosine(2-amino-4-hydroxy-1,3,5-triazine) Cytosine Impurity 1 Decitabine Impurity 49 Azacitidine USP Related Compound A Azacetidine Related Compound A (Hydrate) 5-Azacytosine Hydrate> Decitabine Impurity 49 (5-Azacytosine) 1,3,5-Triazin-2(1H)-one, 6-amino- 5-Azacytosine ISO 9001：2015 REACH Azacitidine Related Compound A (5-Aza Cytosine/ Decitabine Triazinone Impurity) Decitabine Triazinone Impurity (Azacitidine Related Compound A/ 5-Aza Cytosine) 5-AzacytosineQ: What is 5-Azacytosine Q: What is the CAS Number of 5-Azacytosine Q: What is the storage condition of 5-Azacytosine Q: What are the applications of 5-Azacytosine 1,3,5-Triazin-2(1H)-one, 4-amino- 4-Amino-1,3,5-triazin-2(5H)-one Azacitidine Related Compound A (4-Amino-1,3,5-triazin-2(1H)-one) (1045539) 4-aMino-1,3,5-triazin-2-ol 4-amino-1,3,5-triazin-2(1h)-one