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Cytosine

Cytosine
Cytosine structure
CAS No.
71-30-7
Chemical Name:
Cytosine
Synonyms
Cyt;Cytosin;Zytosin;CITOSINA;CYTOSINE;NSC 27787;Cytosine,98%;Cytosinimine;Cytosine API;AURORA KA-682
CBNumber:
CB3746093
Molecular Formula:
C4H5N3O
Formula Weight:
111.1
MOL File:
71-30-7.mol

Cytosine Properties

Melting point:
>300 °C(lit.)
Boiling point:
208.2°C (rough estimate)
Density 
0,48 g/cm3
refractive index 
1.5000 (estimate)
storage temp. 
Store at RT.
solubility 
Clear to very slightly hazy colorless to faint yellow solution at 50 mg/ml in 0.5 M HCL.
form 
Crystalline Powder
pka
4.60, 12.16(at 25℃)
color 
White to slightly yellow
Water Solubility 
soluble
Merck 
14,2795
BRN 
2637
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
OPTASPLRGRRNAP-UHFFFAOYSA-N
CAS DataBase Reference
71-30-7(CAS DataBase Reference)
NIST Chemistry Reference
2(1H)-Pyrimidinone, 4-amino-(71-30-7)
EPA Substance Registry System
2(1H)-Pyrimidinone, 4-amino-(71-30-7)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-37/39
WGK Germany  1
RTECS  UW7350150
Hazard Note  Irritant
TSCA  Yes
HS Code  29335910
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Cytosine price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C3506 Cytosine ≥99% 71-30-7 1g $45.6 2018-11-13 Buy
Sigma-Aldrich 1162148 Cytosine United States Pharmacopeia (USP) Reference Standard 71-30-7 100mg $356 2018-11-13 Buy
TCI Chemical C0528 Cytosine >98.0%(HPLC)(T) 71-30-7 5g $22 2018-11-22 Buy
TCI Chemical C0528 Cytosine >98.0%(HPLC)(T) 71-30-7 25g $66 2018-11-22 Buy
Alfa Aesar A14731 Cytosine, 98+% 71-30-7 25g $156 2018-11-13 Buy

Cytosine Chemical Properties,Uses,Production

Description

Cytosine is pyrimidine; along with adenine and guanine they account for the fi ve nucleic acid bases. Pyrimidines are heterocyclic single-ringed compounds based on the structure of pyrimidine. Cytosinelike adenine and guanine, form nucleosides and nucleotides in RNA and DNA. When the bases combine with ribose, a ribonucleoside forms; and when it attaches to deoxyribose, a deoxyribosenucleoside is formed. Names of the nucleoside are summarized in Table 29.1.these in turn combine with phosphoryl groups, in a process called phosphorylation, to form their respective nucleotides that form nucleic acids.the nucleotides can be tri, di, and mono phosphate nucleotides similar to the way in which adenine forms ATP, ADP, and AMP.

Chemical Properties

White Solid

History

Cytosine is first isolated by hydrolysis of calf thymus tissue by Albrecht Kossel (1853–1927) and A. Neumann during 1893–1894. Thymine’s structure was published in 1900 and confi rmed over the next several years when it was synthesized by several investigators. In 1903, cytosine was synthesized by Henry Lord Wheeler (1867–1914) and Treat B. Johnson, confirming its structure. Uracil was first isolated in 1900 from yeast nucleic acid found in bovine thymus and herring sperm.the methylation of uracil produces thymine; thymine is also called 5-methyluracil because methylation takes place at the fi fth carbon in uracil to produce thymine.

Uses

Widely distributed in nature; constituent of nucleic acids

Definition

ChEBI: An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4.

Definition

A nitrogenous base found in DNA and RNA. Cytosine has the pyrimidine ring structure.

Definition

cytosine: A pyrimidine derivative.It is one of the principal componentbases of nucleotides and the nucleicacids DNA and RNA.

Purification Methods

Cytosine crystallises from H2O as the monohydrate which loses water on heating above 100o. Its solubility in H2O is 0.77%. UV: max 267nm ( 6,100) in H2O pH 8.8 and 275nm ( 10,400) in 0.1N HCl. [Hilbert & Johnson J Am Chem Soc 52 1152 1930, Hilbert et al. J Am Chem Soc 57 552 1935, Beistein 25 III/IV 3654.]

Cytosine Preparation Products And Raw materials

Raw materials

Preparation Products


Cytosine Suppliers

Global( 428)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Zhengzhou Yuanli Biological Technology Co., Ltd
0086-371-67897895
info@zzyuanli.cn CHINA 124 58
Capot Chemical Co.,Ltd.
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+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
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Dalian Richfortune Chemicals Co., Ltd
86-411-84820922, 84821539
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Mainchem Co., Ltd.
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PI & PI BIOTECH INC.
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Hubei XinRunde Chemical Co., Ltd.
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View Lastest Price from Cytosine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-16 Cytosine
71-30-7
US $7.00 / KG 1KG 99% 1000KG career henan chemical co
2018-08-16 Cytosine
71-30-7
US $7.00 / KG 1KG 99% 1000KG career henan chemical co
2018-08-15 Cytosine
71-30-7
US $2.00 / KG 1KG 98% 1ton career henan chemical co

Cytosine Spectrum


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