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4'-Bromoacetanilide

Description Uses
4'-Bromoacetanilide
4'-Bromoacetanilide structure
CAS No.
103-88-8
Chemical Name:
4'-Bromoacetanilide
Synonyms
Asepsin;usafdo-40;USAF do-40;ANTISEPSIN;Bromanilide;Bromoanalide;BROMOANILIDE;Bromoantifebrin;Bromcantifebrin;Bromoacetanilide
CBNumber:
CB6483098
Molecular Formula:
C8H8BrNO
Formula Weight:
214.06
MOL File:
103-88-8.mol

4'-Bromoacetanilide Properties

Melting point:
165-169 °C(lit.)
Boiling point:
353.4°C (estimate)
Density 
1.72
refractive index 
1.6120 (estimate)
storage temp. 
Store below +30°C.
solubility 
alcohol: moderately soluble
form 
Crystalline Powder or Crystals
pka
14.25±0.70(Predicted)
color 
White to beige or light gray
Water Solubility 
Insoluble
Merck 
14,1399
BRN 
2208091
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
103-88-8(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
4KB44F25A3
NIST Chemistry Reference
Acetamide, N-(4-bromophenyl)-(103-88-8)
EPA Substance Registry System
Acetamide, N-(4-bromophenyl)- (103-88-8)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280g-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  2811
WGK Germany  3
RTECS  AD9625000
Hazard Note  Irritant
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29242998

4'-Bromoacetanilide price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 161659 4-Bromoacetanilide 98% 103-88-8 25g $53.5 2021-03-22 Buy
Sigma-Aldrich 8.21967 4′-Bromoacetanilide for synthesis 103-88-8 100 g $69.93 2021-03-22 Buy
Sigma-Aldrich 161659 4-Bromoacetanilide 98% 103-88-8 100g $189 2021-03-22 Buy
TCI Chemical B0534 4'-Bromoacetanilide >98.0%(GC) 103-88-8 25g $68 2021-03-22 Buy
TCI Chemical B0534 4'-Bromoacetanilide >98.0%(GC) 103-88-8 100g $156 2021-03-22 Buy

4'-Bromoacetanilide Chemical Properties,Uses,Production

Description

4'-Bromoacetanilide is a Pale yellow crystals or powdery crystals.Melting point 168℃, relative density 1.717.Soluble in benzene, chloroform, ethyl acetate, slightly soluble in alcohol, slightly soluble in hot water, insoluble in cold water. It can be used as reparation of 4'-Bromoacetanilide from Acetanilide.
Principle: Aromatic compounds can be conveniently brominated by the use of brominating agent, which is normally a solution of bromine in acetic acid. Bromination of activated aromatic compounds usually give 2, 4, 6-tribromo derivatives while moderately activating group like anilide give preferably the para bromo product.

Uses

4'-Bromoacetanilide can be used as an intermediate in organic synthesis.

Chemical Properties

4'-Bromoacetanilide is a white to light beige crystalline solid.

Preparation

Preparation of 4'-Bromoacetanilide from Acetanilide.
Principle: Aromatic compounds can be conveniently brominated by the use of brominating agent, which is normally a solution of bromine in acetic acid. Bromination of activated aromatic compounds usually give 2, 4, 6-tribromo derivatives while moderately activating group like anilide give preferably the para bromo product.
Reaction:
Preparation of 4'-Bromoacetanilide from Acetanilide
Procedure: Dissolve 0.5 g acetanilide in 0.6 ml glacial acetic acid and add 2.5 ml bromine solution in acetic acid (25% w/v). Shake the mixture for 1 h. After 1 h, pour the mixture on to crushed ice (20 g) with stirring. Filter the separated product and wash with cold water. Dry the product, record the practical yield and re-crystallize it.
Re-crystallization: Dissolve the crude product in minimum amount of ethyl alcohol in a beaker by heating on a water bath. Filter the hot solution and cool the filtrate. The crystals of the product separate out. Filter, dry and record the melting point and TLC (using toluene as a solvent).

Synthesis Reference(s)

Canadian Journal of Chemistry, 50, p. 1233, 1972 DOI: 10.1139/v72-193
Synthetic Communications, 23, p. 779, 1993 DOI: 10.1080/00397919308009839

Purification Methods

Crystallise the anilide from aqueous MeOH or EtOH. Purify it by zone refining. [Beilstein 12 IV 1504.]

4'-Bromoacetanilide Preparation Products And Raw materials

Raw materials

Preparation Products


4'-Bromoacetanilide Suppliers

Global( 163)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21022 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29959 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2858 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47496 58
Richest Group Ltd
18017061086
oled@richest-group.com CHINA 5606 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17607 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
0551-65418697 sales@tnjchem.com CHINA 37441 58

View Lastest Price from 4'-Bromoacetanilide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-06 4'-Bromoacetanilide
103-88-8
US $8.00 / kg 1kg 99% 10TON career henan chemical co

4'-Bromoacetanilide Spectrum


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