4'-Bromacetanilid
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- CAS-Nr.
- 103-88-8
- Bezeichnung:
- 4'-Bromacetanilid
- Englisch Name:
- 4'-Bromoacetanilide
- Synonyma:
- Asepsin;usafdo-40;USAF do-40;ANTISEPSIN;Bromanilide;Bromoanalide;BROMOANILIDE;Bromcantifebrin;Bromoantifebrin;Bromoacetanilide
- CBNumber:
- CB6483098
- Summenformel:
- C8H8BrNO
- Molgewicht:
- 214.06
- MOL-Datei:
- 103-88-8.mol
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4'-Bromacetanilid Eigenschaften
- Schmelzpunkt:
- 165-169 °C(lit.)
- Siedepunkt:
- 353.4°C (estimate)
- Dichte
- 1.72
- Brechungsindex
- 1.6120 (estimate)
- storage temp.
- Store below +30°C.
- Löslichkeit
- alcohol: moderately soluble
- Aggregatzustand
- Crystalline Powder or Crystals
- pka
- 14.25±0.70(Predicted)
- Farbe
- White to beige or light gray
- Wasserlöslichkeit
- Insoluble
- Merck
- 14,1399
- BRN
- 2208091
- Stabilität:
- Stable. Incompatible with strong oxidizing agents.
- CAS Datenbank
- 103-88-8(CAS DataBase Reference)
- NIST chemische Informationen
- Acetamide, N-(4-bromophenyl)-(103-88-8)
- EPA chemische Informationen
- Acetamide, N-(4-bromophenyl)- (103-88-8)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi |
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| R-Sätze: |
36/37/38 |
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| S-Sätze: |
26-36 |
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| RIDADR |
2811 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
AD9625000 |
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| Hazard Note |
Irritant |
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| TSCA |
Yes |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
29242998 |
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| Toxizität |
mouse,LD50,intraperitoneal,250mg/kg (250mg/kg),National Technical Information Service. Vol. AD277-689, |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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4'-Bromacetanilid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
4'-Bromoacetanilide is a white to light beige crystalline solid with a melting point of 168°C and a relative density of 1.717. It is soluble in benzene, chloroform, and ethyl acetate, slightly soluble in alcohol and hot water, and insoluble in cold water. This compound can be prepared by brominating acetanilide and is commonly used as an intermediate in organic synthesis.
Verwenden
4'-Bromoacetanilide is used as an internal standard for phenylurea and the respective metabolic products in oysters. It has also been used as a reagent in the production of a new ligand to form a coordination compex between gadolinium(III) and T=titanium(IV) oxide. It was used in the synthesis of new ligand for anchoring Gd(III) chelates onto TiO2 surface.
synthetische
Preparation of 4'-Bromoacetanilide from Acetanilide.
Principle: Aromatic compounds can be conveniently brominated by the use of brominating agent, which is normally a solution of bromine in acetic acid. Bromination of activated aromatic compounds usually give 2, 4, 6-tribromo derivatives while moderately activating group like anilide give preferably the para bromo product.
Reaction:
Procedure: Dissolve 0.5 g acetanilide in 0.6 ml glacial acetic acid and add 2.5 ml bromine solution in acetic acid (25% w/v). Shake the mixture for 1 h. After 1 h, pour the mixture on to crushed ice (20 g) with stirring. Filter the separated product and wash with cold water. Dry the product, record the practical yield and re-crystallize it.
Re-crystallization: Dissolve the crude product in minimum amount of ethyl alcohol in a beaker by heating on a water bath. Filter the hot solution and cool the filtrate. The crystals of the product separate out. Filter, dry and record the melting point and TLC (using toluene as a solvent).
läuterung methode
Crystallise the anilide from aqueous MeOH or EtOH. Purify it by zone refining. [Beilstein 12 IV 1504.]
4'-Bromacetanilid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4'-Bromacetanilid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 276)Lieferanten
103-88-8(4'-Bromacetanilid)Verwandte Suche:
- Aceto-p-bromoanilide
- Acet-p-bromoanilide
- Asepsin
- Bromanilide
- Bromcantifebrin
- Bromoacetanilide
- Bromoanalide
- Bromoantifebrin
- Monobromoacetamalide
- n-(4-bromophenyl)-acetamid
- N-(p-Bromophenyl)acetamide
- p-Bromoacetanalide
- p-bromo-acetanilid
- p-Bromo-N-acetanilide
- USAF do-40
- usafdo-40
- BROMOANILIDE
- ANTISEPSIN
- 4'-BROMOACETANILIDE
- 4-BROMOACETANILIDE
- 4-BROMOACETOANILIDE
- Bromoacetoanilide
- Monobromoacetanilide
- P-BROMOACETANILIDE, 98% (SEE 1735)
- 4-Bromoacetanylide
- Acetamide, N-(4-bromophenyl)-
- p-BROMOACETANILIDE pure
- 4'-Bromoacetanilide,98%
- 4-Bromoacetanilide, 98% PS
- N-Acetyl-4-bromoaniline, N-(4-Bromophenyl)acetamide
- P-ACETAMIDOPHENYL BROMIDE
- P-BROMOACETANILIDE
- N-ACETYL-4-BROMOANILINE
- N-ACETYL-P-BROMOANILINE
- N-(4-BROMO-PHENYL)-ACETAMIDE
- 1-(N-Acetylamino)-4-bromobenzene
- 1-Bromo-4-acetamidobenzene
- 4’-bromo-acetanilid
- 4'-Bromoacetanilide 250
- Acetamide, N-(p-bromophenyl)-
- Acetanilide, 4'-bromo-
- Acetanilide, p-bromo-
- Bromine acetanilide
- Para Bromo Acetanilide 98%
- 4'-Bromoacetanilide >
- 4'-BROMOACETANILIDE FOR SYNTHESIS
- Parabromoacetanilide
- TIANFU-CHEM 103-88-8 4'-Bromoacetanilide
- PARA BROMO ACETANILIDE (PBA)
- 4'-Bromoacetanilide
- 103-88-8
- C8H8BrNO
- BrC6H4NHCOCH3
- CH3CONHC6H4Br
- Organic Building Blocks
- Nitrogen Compounds
- Protected Amines
- Building Blocks
