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(S)-AMPA

(S)-AMPA structure

CAS No.: 83643-88-3

Chemical Name:: (S)-AMPA

Synonyms: AMQ;(S)-AMPA;glutamate-AMPA;L-AMPA, S-AMPA;(S) AMPA,(S)AMPA;(S)-AMPA (mM/ml);(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio;(S)-amino-3-hydroxy-5-methylisoxazolepropionic acid;(S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI;(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid

CBNumber:: CB6711838

Molecular Formula:: C7H10N2O4

Molecular Weight:: 186.17

MDL Number:: MFCD00672630

MOL File:: 83643-88-3.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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(S)-AMPA Properties

alpha	D28 -21 ±2° (c = 0.19 in water)
Density	1.386±0.06 g/cm3(Predicted)
storage temp.	Store at RT
form	White to off-white powder.
pka	2.15±0.10(Predicted)
color	White
Water Solubility	Soluble to 100 mM in water
CAS DataBase Reference	83643-88-3(CAS DataBase Reference)
FDA UNII	9280SC28GD

SAFETY

Risk and Safety Statements

Risk Statements	36/37/38
Safety Statements	26-36/37/39
WGK Germany	3

(S)-AMPA price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A0326	(S)-AMPA ≥98%	83643-88-3	1mg	$246	2024-03-01	Buy
Sigma-Aldrich	A0326	(S)-AMPA ≥98%	83643-88-3	5mg	$847	2024-03-01	Buy
Alfa Aesar	J65847	(S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	83643-88-3	5mg	$176	2021-12-16	Buy
Tocris	0254	(S)-AMPA ≥99%(HPLC)	83643-88-3	10	$279	2021-12-16	Buy
Tocris	0254	(S)-AMPA ≥99%(HPLC)	83643-88-3	50	$1109	2021-12-16	Buy

Product number	Packaging	Price	Buy
A0326	1mg	$246	Buy
A0326	5mg	$847	Buy
J65847	5mg	$176	Buy
0254	10	$279	Buy
0254	50	$1109	Buy

(S)-AMPA Chemical Properties,Uses,Production

Uses

Active enantiomer of AMPA that induces apoptosis in cortical neurons

Uses

(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.

Uses

(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.

General Description

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).

Biological Activity

Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ .

Biochem/physiol Actions

Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.

storage

Room temperature

(S)-AMPA Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-AMPA Suppliers

Global( 75)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11605	64
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35906	56

Supplier	Advantage
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Nextpeptide Inc	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64
Mainchem Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Wuhan Chemwish Technology Co., Ltd	56

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(S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (S)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID (S)-AMPA (S)-amino-3-hydroxy-5-methylisoxazolepropionic acid (S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio (S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI (s)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazol-propionic acid (2S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (2S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (2S)-2-amino-3-(3-keto-5-methyl-isoxazol-4-yl)propionic acid (2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid (2S)-2-azanyl-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid (S)-2-aMino-3-(3-hydroxy-5-Methylisoxazol-4-yl)propanoic acid (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid (2S)-2-amino-3-(5-methyl-3-oxo-4-isoxazolyl)propanoic acid AMQ;GLUTAMATE-AMPA;(S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID glutamate-AMPA 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (αS)- (S)-2-Amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid AMQ L-AMPA, S-AMPA (S) AMPA,(S)AMPA (S)-AMPA (mM/ml) 83643-88-3 C7H10NO5 BioChemical Cell Signaling and Neuroscience Cell Biology Ionotropic Glutamate Receptor Modulators Ion Channels Ligand-Gated Ion Channels Glutamate receptor Apoptosis Inducers Glutamate