L-Sulforaphane
- CAS No.
- 142825-10-3
- Chemical Name:
- L-Sulforaphane
- Synonyms
- NSC47734;NSC 47734;NSC-47734;sulphorane;L-SULFORAPHAN;S-SULFORAPHANE;R-SULFORAPHANE;D-SULFORAPHANE;L-SULFORAPHANE;R,S-SULFORAPHANE
- CBNumber:
- CB6765543
- Molecular Formula:
- C6H11NOS2
- Molecular Weight:
- 177.29
- MDL Number:
- MFCD09039283
- MOL File:
- 142825-10-3.mol
- MSDS File:
- SDS
| Boiling point | 368.2±25.0 °C(Predicted) |
|---|---|
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: 40 mg/mL, soluble |
| form | liquid |
| color | slightly yellow |
| InChIKey | SUVMJBTUFCVSAD-UHFFFAOYSA-N |
| FDA UNII | GA49J4310U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H334-H335 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P284-P302+P352-P342+P311-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P304+P340+P312-P403+P233-P405 | |||||||||
| Safety Statements | 23-24/25-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
L-Sulforaphane price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S6317 | L-Sulforaphane ≥95% (HPLC), oil | 142825-10-3 | 5mg | $279 | 2024-03-01 | Buy |
| Cayman Chemical | 14797 | L-Sulforaphane ≥98% | 142825-10-3 | 1mg | $45 | 2024-03-01 | Buy |
| Cayman Chemical | 14797 | L-Sulforaphane ≥98% | 142825-10-3 | 5mg | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 14797 | L-Sulforaphane ≥98% | 142825-10-3 | 10mg | $177 | 2024-03-01 | Buy |
| Cayman Chemical | 14797 | L-Sulforaphane ≥98% | 142825-10-3 | 50mg | $698 | 2024-03-01 | Buy |
L-Sulforaphane Chemical Properties,Uses,Production
Description
Sulforaphane is a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale.
Chemical Properties
L-Sulforaphane is a clear Pale Yellow Oil and It is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli. soluble in methanol, ethanol, DMSO and other organic solvents.
Uses
L-sulforaphane is an Antitumor agent and has antioxidant, anti-cancer, anti-ultraviolet, help clear lung bacteria, and prevent gout. It was found to inhibit chemically induced mammary tumor formation in rats. L-Sulforaphane has been reported to prevent NFκB binding, which results in downregulation of apoptosis inhibitors therefore inducing apoptosis. It also displays a capacity to inhibit intracellular, extracellular, and antibiotic-resistant strains of Helicobacter pylori. Additionally, L-Sulforaphane has been found to prevent clonogenicity. This Sulforaphane is sold in the L-enantiomer form.
Application
L-Sulforaphane was used to study Nrf2-mediated signaling in mouse primary preadipocytes and murine macrophage RAW 264.7 cell line.
Definition
ChEBI: (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.
Biochem/physiol Actions
L-Sulforaphane is a potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.
Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.
L-Sulforaphane Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 282 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Related articles
- L-Sulforaphane: mechanism of action and clinical applications
- L-Sulforaphane from cruciferous vegetables activates antioxidant and anti-inflammatory pathways, showing potential for medical....
- Nov 30，2023
- (R)-sulforaphane- Pharmacologic Action
- Sulforaphane (SFN) is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces th....
- Dec 17，2019
View Lastest Price from L-Sulforaphane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | L-Sulforaphane
142825-10-3
|
US $0.00 / KG | 1KG | 0.6%-98% HP0LC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-04-22 | Sulforaphane
142825-10-3
|
US $0.00 / kg | 1kg | 1%-10% 98% | 1000 kg | BINBO BIOLOGICAL CO.,LTD | |
 |
2021-10-27 | Sulforaphane
142825-10-3
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd |
-
- L-Sulforaphane
142825-10-3
- US $0.00 / KG
- 0.6%-98% HP0LC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Sulforaphane
142825-10-3
- US $0.00 / kg
- 1%-10% 98%
- BINBO BIOLOGICAL CO.,LTD
-
- Sulforaphane
142825-10-3
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd