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ALLOXAN MONOHYDRATE

CAS No.
2244-11-3
Chemical Name:
ALLOXAN MONOHYDRATE
Synonyms
Alloxan99%;MESOXALYLUREA;Alloxan, 98.5%;5,6-DIOXYURACIL;Urea monohydrate;ALLOXANE DIHYDRATE;ALLOXAN MONOHYDRATE;Alloxan Momohydrate;ALLOXAN ( HYDRATE) GR;LABOTEST-BB LT00138148
CBNumber:
CB6771957
Molecular Formula:
C4H4N2O5
Molecular Weight:
160.09
MDL Number:
MFCD00149399
MOL File:
2244-11-3.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:18

ALLOXAN MONOHYDRATE Properties

Melting point 255 °C (dec.)(lit.)
storage temp. 2-8°C
solubility H2O: may be hazy yellow
form Crystalline Powder
color Off-white to beige-yellow
Water Solubility Soluble in water, ethanol, acetone, glacial acetic acid and methanol. Slightly soluble in chloroform, petroleum ether, toluene, ethyl acetate and acetic anhydride. Insoluble in ether.
Sensitive Air Sensitive
Merck 14,282
BRN 5309394
CAS DataBase Reference 2244-11-3(CAS DataBase Reference)
FDA UNII O2AAP9F8B6
EPA Substance Registry System 2,4,5,6(1H,3H)-Pyrimidinetetrone, monohydrate (2244-11-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  36-26-36/37
WGK Germany  3
RTECS  UW0492000
TSCA  Yes
HS Code  29335995
NFPA 704
0
1 0

ALLOXAN MONOHYDRATE price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A7413 Alloxan monohydrate 98% 2244-11-3 10g $51 2024-03-01 Buy
Sigma-Aldrich A7413 Alloxan monohydrate 98% 2244-11-3 25g $79.4 2024-03-01 Buy
TCI Chemical A0216 Alloxan Monohydrate 2244-11-3 5G $36 2024-03-01 Buy
TCI Chemical A0216 Alloxan Monohydrate >98.0%(T) 2244-11-3 25g $109 2024-03-01 Buy
Alfa Aesar A15324 Alloxan monohydrate, 98% 2244-11-3 25g $54.9 2023-06-20 Buy
Product number Packaging Price Buy
A7413 10g $51 Buy
A7413 25g $79.4 Buy
A0216 5G $36 Buy
A0216 25g $109 Buy
A15324 25g $54.9 Buy

ALLOXAN MONOHYDRATE Chemical Properties,Uses,Production

Chemical Properties

Off-white to beige-yellowish crystalline powder

Uses

specific cytotoxin (beta pacreatic cell)

Uses

Cytotoxic compound that causes oxidative base damage to nuclear DNAAlloxan monohydrate is used as a precursor to prepare purple dye murexide. It is also used in research models to induce diabetes and destroy beta cells. Further, it is a strong oxidizing agent and it forms a hemiacetal with its reduced reaction product dialuric acid.

Uses

A cytotoxic compound, Alloxan Monohydrate causes oxidative base damage to nuclear DNA.

Safety Profile

Poison by intravenous route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Recrystallisation from H2O gave the tetrahydrate in large prisms or rhombs. On heating at 100o, or on exposure to air, this is converted to the monohydrate. Dissolve it in its own weight of boiling H2O and cool it for several days below 0o; the tetrahydrate crystallises from solution much more slowly when free from HNO3. It is less soluble in bicarbonate solutions than in H2O. Drying the solid over H2SO4 yields the monohydrate. The anhydrous crystals can be obtained by recrystallisation from dry Me2CO or AcOH followed by washing with dry Et2O, or by sublimation in a vacuum. On heating it turns pink at 230o and decomposes at ca 256o. It is acidic to litmus. [Hartman & Sheppard Org Synth Coll Vol III 37 1955.] It forms a compound with urea which crystallises from H2O in yellow needles that become red at 170o and decompose at 185-186o. [Beilstein 24 H 500, 24 I 428, 24 II 301, 24 III/IV 2137.]

ALLOXAN MONOHYDRATE Preparation Products And Raw materials

Global( 204)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29118 58

View Lastest Price from ALLOXAN MONOHYDRATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Alloxan Monohydrate pictures 2023-02-07 Alloxan Monohydrate
2244-11-3
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
ALLOXAN MONOHYDRATE pictures 2023-01-31 ALLOXAN MONOHYDRATE
2244-11-3
US $100.00 / kg 1kg 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
ALLOXAN MONOHYDRATE pictures 2020-02-04 ALLOXAN MONOHYDRATE
2244-11-3
US $1.00 / KG 1KG 98-99.9% 100kg Career Henan Chemical Co
5,6-DIOXYURACIL MONOHYDRATE ALLOXANE DIHYDRATE ALLOXAN MONOHYDRATE 2,4,5,6-TETRAOXYPYRIMIDINE 2,4,5,6-TETRAOXYPYRIMIDINE MONOHYDRATE 2,4,5,6(1H,3H)-PYRIMIDINETETRONE MONOHYDRATE Alloxan99% ALLOXAN ( HYDRATE) GR Pyrimidine-2,4,5,6(1H,3H)-tetrone hydrate 2,4,5,6(1h,3h)-pyrimidinetetronehydrate Alloxan monohydrate,98% Alloxan Momohydrate Alloxan Monohydrate, 98% 25GR PyriMidine-2,4,5,6(1H,3H)-tetraone hydrate 1,3-Diazinane-2,4,5,6-tetrone hydrate Alloxan monohydrate ,99% 2,4,5,6(1H,3H)-PyriMidinetetrone,hydrate (1:1) Alloxan monohydrate≥ 98% (Assay) 2,4,5,6(1H,3H)-Pyrimidinetetrone monohydrate 2,4,5,6(1H,3H)-Pyrimidinetetrone monohydrate 2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil 2,4,5,6-tetraoxohexahydropyrimidinehydrate mesoxalylcarbamidemonohydrate LABOTEST-BB LT00138148 MESOXALYLUREA MESOXALYLUREA, MONOHYDRATE 5,6-DIOXYURACIL Urea monohydrate Alloxan Monohydrate> ALLOXAN MONOHYDRATE USP/EP/BP Alloxan, 98.5% Alloxan Monohydrate extrapure, 98% N-[(E)-3-methylbutylideneamino]-2,4-dinitroaniline Alloxan Monohydrate, ≥ 98.0% 2244-11-3 2244-13-3 2244-11-03 125-95-2 CONHCONHCOCOH2 C4H2N2O4xH2O C4H2N2O4H2O Building Blocks Heterocyclic Building Blocks Pyrimidines buildingblock Pyridines, Pyrimidines, Purines and Pteredines Active Pharmaceutical Ingredients