Beclobrate
- CAS No.
- 55937-99-0
- Chemical Name:
- Beclobrate
- Synonyms
- Turec;Beclipur;Sgd-24774;Beclobrate;Beclobrate USP/EP/BP;Ethyl 2-(4-(4-chlorobenzyl)phenoxy)-2-Methylbutanoate;Ethyl(±)-2-[[α(-(4-chlorophenyl)-4-tolyl]oxy]-2-methylbutyrate;2-[4-(4-Chlorobenzyl)phenoxy]-2-methylbutyric acid ethyl ester;Butanoic acid, 2-[4-[(4-chlorophenyl)Methyl]phenoxy]-2-Methyl-, ethyl ester
- CBNumber:
- CB6875424
- Molecular Formula:
- C20H23ClO3
- Molecular Weight:
- 346.85
- MDL Number:
- MFCD00865758
- MOL File:
- 55937-99-0.mol
- MSDS File:
- SDS
Boiling point | bp0.01-0.1 200-204° |
---|---|
storage temp. | 2-8°C |
FDA UNII | USZ5MY269R |
Beclobrate price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0001599 | BECLOBRATE 95.00% | 55937-99-0 | 100MG | $1030.84 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001599 | BECLOBRATE 95.00% | 55937-99-0 | 1G | $1904.7 | 2021-12-16 | Buy |
Crysdot | CD31001475 | Beclobrate 95+% | 55937-99-0 | 1g | $947 | 2021-12-16 | Buy |
Beclobrate Chemical Properties,Uses,Production
Description
Beclobrate is a hypolipidemic agent related structurally to clofibrate. It is reportedly useful in types IIa-V hyperlipoproteinemias, promoting normalization of t h e atherogenic index.
Originator
Siegfried AG (Switzerland)
Definition
ChEBI: Beclobrate is a diarylmethane.
Manufacturing Process
87.0 g (0.4 mol) of 4-chloro-4'-hydroxydiphenylmethane are heated together with 27.0 g (0.2 mol) of anhydrous potassium carbonate in 350 ml of anhydrous xylene for 30 min to reflux temperature, whereafter a solution of 83.5 g (0.4 mol) of 2-bromo-2-ethyl-2-methyl acetic acid ethyl ester in 50 ml of anhydrous xylene is added. The mixture is kept for 24 hours and with vigorous stirring at reflux temperature. After filtering off the precipitated potassium bromide and evaporating the solvent in a Buchi rotary evaporator, the residue is taken up in ether and extracted with normal sodium hydroxide solution. The ether extracts are washed with water, dried over MgSO4 and concentrated by evaporation. The brown oil (82.0 g) thereby obtained is dissolved in n-hexane and filtered through a column of 200 g of basic Al2O3. After evaporating the solvent and distillation at reduced pressure, 34.7 g of pure ethyl (+/-)-2-((α-(p-chlorophenyl)-p-tolyl)oxy)-2-methylbutyrate are obtained with the boiling point 200-204°C/0.01-0.1 mm Hg.
brand name
BECLOSCLERIN
Therapeutic Function
Antihyperlipidemic
World Health Organization (WHO)
Beclobrate, an antihyperlipidaemic agent, was introduced into medicine in 1985. Although a causal relationship between the use of the drug and hepatic toxicity has not been established, the Intercantonal Office for the Control of Medicines has withdrawn marketing authorization since safer therapeutic alternatives are available. Beclobrate is not registered elsewhere.
Beclobrate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27644 | 58 |
Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10269 | 58 |
SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
Aikon International Limited | 025-66113011 18112977050 | cb6@aikonchem.com | China | 15495 | 58 |
Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3245 | 58 |
Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4394 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
Shaanxi Istare Biotechnology Co., Ltd. | 029-81530825 18682931470 | 2142355700@qq.com | China | 1458 | 58 |
View Lastest Price from Beclobrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-08-06 | Beclobrate USP/EP/BP
55937-99-0
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | ||
2020-05-12 | Beclobrate
55937-99-0
|
US $0.00-0.00 / KG | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
- Beclobrate USP/EP/BP
55937-99-0
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- Beclobrate
55937-99-0
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd