Chinese Japanese Germany Korea


Chemical Name:
DPNA;NSC 133;rcrawastenumberu111;DIPROPYLNITROSAMINE;nitrosodipropylamin;Nitrosodipropylamine;nitrous dipropylamide;Di-n-prpylnitrosamine;Rcra waste number U111;n-nitroso-dipropylamin
Molecular Formula:
Formula Weight:
MOL File:


Boiling point:
113 °C / 40mmHg
refractive index 
1.4468 (589.3 nm 20℃)
Flash point:
10 °C
storage temp. 
Very soluble in ethanol and ether (quoted, Keith and Walters, 1992)
Yellow to gold colored liquid
Water Solubility 
9,900 mg/L at 25 °C (Mirvish et al., 1976)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,N,F
Risk Statements  45-22-51/53-39/23/24/25-23/24/25-11
Safety Statements  53-45-61-36/37-16
RIDADR  2810
WGK Germany  3
RTECS  JL9700000
HazardClass  6.1(b)
PackingGroup  III
Toxicity Acute oral LD50 for rats 480 mg/kg (quoted, RTECS, 1985).
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P391 Collect spillage. Hazardous to the aquatic environment
P308+P313 IF exposed or concerned: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P501 Dispose of contents/container to..…


Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 48554 N-Nitrosodi-n-propylamine analytical standard 621-64-7 48554 $37.6 2018-11-23 Buy
Sigma-Aldrich 40061 N-Nitrosodi-n-propylamine solution certified reference material, 5000 μg/mL in methanol 621-64-7 40061 $44.6 2018-11-23 Buy
TCI Chemical N0444 N-Nitrosodipropylamine >98.0%(GC) 621-64-7 5g $114 2018-11-22 Buy
TCI Chemical N0444 N-Nitrosodipropylamine >98.0%(GC) 621-64-7 25g $310 2018-11-22 Buy

N-NITROSODI-N-PROPYLAMINE Chemical Properties,Uses,Production

Chemical Properties

Yellow Oil

Chemical Properties

N-nitrosodi-N-propylamine is a yellow liquid.


N-Nitrosodi-n-propylamine is used in small quantities in laboratory research. It has no known commercial use (IARC 1978, ATSDR 1989, HSDB 2009).

General Description

Clear to pale yellow liquid.

Reactivity Profile

N-NITROSODI-N-PROPYLAMINE is a nitrated amine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard


Fire Hazard

Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

Potential Exposure

N-nitrosodi-N-propylamine is used in the manufacture of plastics, resins, rubber, and synthetic textiles. There is no evidence that N-nitrosodi-N-propylamine exists naturally in soil, air, food, or water. Small quantities of N-nitrosodi-N-propylamine are inadvertently produced during some manufacturing processes; as an impurity in some commercially available dinitroaniline based weed killers, and during the manufacture of some rubber products. However, according to Sax, some similar N-nitroso compounds are formed in the environment and absorbed from precursors in food, water, or air; from tobacco; and from naturally occurring compounds.


N-Nitrosodi-n-propylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Environmental Fate

Chemical/Physical. N-Nitroso-n-propylamine will not hydrolyze because it does not contain a hydrolyzable functional group (Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities were 24, 13, 7.4, and 4.0 mg/g, respectively (Dobbs and Cohen, 1980).


UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required


Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Sensitive to UV light.

Waste Disposal

N-Nitrosodi-N-propylamine may be destroyed by high temperature incineration in an incinerator equipped with an nitrogen oxide scrubber. Chemical treatment methods may also be used to destroy N-nitrosodi-N-propylamine. These methods involve (a) denitrosation by reaction with 3% hydrobromic acid in glacial acetic acid; (b) oxidation by reaction with potassium permanganate-sulfuric acid; or (c) extraction of the nitrosamine from the waste using dichloromethane and subsequent reaction with triethyloxonium tetrafluoroborate (TOEF). Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.


Consumer Product Safety Commission (CPSC)
A voluntary standard provides that rubber pacifiers shall not contain more than 10 ppb of any single nitrosamine or more than 20 ppb of total nitrosamines.
Environmental Protection Agency (EPA)
Clean Water Act
Effluent Guidelines: Nitrosamines are listed as a toxic pollutant. Water Quality Criteria: Based on fish or shellfish and water consumption = 0.0050 μg/L; based on fish or shellfish consumption only = 0.51 μg/L.
Comprehensive Environmental Response, Compensation, and Liability Act Reportable quantity (RQ) = 10 lb.
Emergency Planning and Community Right-To-Know Act Toxics Release Inventory: Listed substance subject to reporting requirements.
Resource Conservation and Recovery Act
Listed Hazardous Waste: Waste code for which the listing is based wholly or partly on the presence of N-nitrosodi-n-propylamine = U111. Listed as a hazardous constituent of waste.
Toxic Substances Control Act
Nitrosating agents distributed in commerce require warning labels and instructions on use.
Food and Drug Administration (FDA)
The action level for N-nitrosamines in rubber baby-bottle nipples is 10 ppb. In order to use nitrites and/or nitrates as food additives in curing premixes, a petition must be filed supported by data demonstrating that nitrosamines are not formed.

N-NITROSODI-N-PROPYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products


Global( 57)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32447 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40269 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 China 15881 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 China 24555 81
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 China 44025 61
Shanghai Longsheng chemical Co.,Ltd. 021-58099637,58099652,58099650,58099609 To 8009,8068; 13585536065,QQ:975986869
0086-21-33191781;; China 9823 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380 China 32362 50
Syntechem Co.,Ltd Please Email
E-Mail Inquiry China 13010 57
Spectrum Chemical Manufacturing Corp. 021-67601398,18616765336,QQ:3003443155
021-57711696 China 9689 60

621-64-7(N-NITROSODI-N-PROPYLAMINE)Related Search:

Copyright 2017 © ChemicalBook. All rights reserved