ChemicalBook >> CAS DataBase List >>N-NITROSODI-N-PROPYLAMINE


Chemical Name:
DPNA;NSC 133;rcrawastenumberu111;DIPROPYLNITROSAMINE;nitrosodipropylamin;Nitrosodipropylamine;nitrous dipropylamide;Di-n-prpylnitrosamine;Di-N-propylnitrosamine;dipropyl-nitroso-amine
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
Last updated:2023-06-08 17:06:38


Boiling point 113 °C / 40mmHg
Density 0.92
refractive index 1.4468 (589.3 nm 20℃)
Flash point 10 °C
storage temp. Inert atmosphere,2-8°C
solubility Very soluble in ethanol and ether (quoted, Keith and Walters, 1992)
pka -3.18±0.70(Predicted)
color Yellow to gold colored liquid
Water Solubility 9,900 mg/L at 25 °C (Mirvish et al., 1976)
EWG's Food Scores 4-7
Proposition 65 List N-Nitrosodi-n-propylamine
IARC 2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System N-Nitrosodi-n-propylamine (621-64-7)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word  Danger
Hazard statements  H302-H350-H411
Precautionary statements  P202-P264-P270-P273-P301+P312-P308+P313
Hazard Codes  T,N,F
Risk Statements  45-22-51/53-39/23/24/25-23/24/25-11
Safety Statements  53-45-61-36/37-16
RIDADR  2810
WGK Germany  3
RTECS  JL9700000
HS Code  2921.29.0055
HazardClass  6.1(b)
PackingGroup  III
Toxicity Acute oral LD50 for rats 480 mg/kg (quoted, RTECS, 1985).
NFPA 704
2 0


Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 48554 N-Nitrosodi-n-propylamine analytical standard 621-64-7 100mg $52.6 2024-03-01 Buy
Sigma-Aldrich 40061 N-Nitrosodi-n-propylamine solution certified reference material, 5000?μg/mL in methanol 621-64-7 1mL $62.3 2024-03-01 Buy
TCI Chemical N0444 N-Nitrosodipropylamine >98.0%(GC) 621-64-7 5g $143 2024-03-01 Buy
TCI Chemical N0444 N-Nitrosodipropylamine >98.0%(GC) 621-64-7 25g $386 2024-03-01 Buy
TRC N525480 N-Nitrosodipropylamine 621-64-7 5g $485 2021-12-16 Buy
Product number Packaging Price Buy
48554 100mg $52.6 Buy
40061 1mL $62.3 Buy
N0444 5g $143 Buy
N0444 25g $386 Buy
N525480 5g $485 Buy

N-NITROSODI-N-PROPYLAMINE Chemical Properties,Uses,Production

Chemical Properties

Yellow Oil

Chemical Properties

N-nitrosodi-N-propylamine is a yellow liquid.


Research chemical; impurity in herbicides treflan, isopropalin, and trifluralin; contaminant in wastewater from chemical factories and production of cheese and brandy and other liquors. N-nitrosamines are frequently produced during rubber processing and may be airborne in the workplace.


N-Nitrosodi-n-propylamine is used in small quantities in laboratory research. It has no known commercial use (IARC 1978, ATSDR 1989, HSDB 2009).


ChEBI: N-Nitrosodi-n-propylamine is a nitroso compound.

General Description

Clear to pale yellow liquid.

Reactivity Profile

N-NITROSODI-N-PROPYLAMINE is a nitrated amine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard


Fire Hazard

Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

Potential Exposure

N-nitrosodi-N-propylamine is used in the manufacture of plastics, resins, rubber, and synthetic textiles. There is no evidence that N-nitrosodi-N-propylamine exists naturally in soil, air, food, or water. Small quantities of N-nitrosodi-N-propylamine are inadvertently produced during some manufacturing processes; as an impurity in some commercially available dinitroaniline based weed killers, and during the manufacture of some rubber products. However, according to Sax, some similar N-nitroso compounds are formed in the environment and absorbed from precursors in food, water, or air; from tobacco; and from naturally occurring compounds.


N-Nitrosodi-n-propylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Environmental Fate

Chemical/Physical. N-Nitroso-n-propylamine will not hydrolyze because it does not contain a hydrolyzable functional group (Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities were 24, 13, 7.4, and 4.0 mg/g, respectively (Dobbs and Cohen, 1980).


UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required


Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Sensitive to UV light.

Waste Disposal

N-Nitrosodi-N-propylamine may be destroyed by high temperature incineration in an incinerator equipped with an nitrogen oxide scrubber. Chemical treatment methods may also be used to destroy N-nitrosodi-N-propylamine. These methods involve (a) denitrosation by reaction with 3% hydrobromic acid in glacial acetic acid; (b) oxidation by reaction with potassium permanganate-sulfuric acid; or (c) extraction of the nitrosamine from the waste using dichloromethane and subsequent reaction with triethyloxonium tetrafluoroborate (TOEF). Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

N-NITROSODI-N-PROPYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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guoyungurui 18162595016 China 10012 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 96815 76
N,N-dipropylnitrous amide N-Nitrosodi-n-propylamine 1g [621-64-7] N-Nitroso-N-di-n-propylaMine NSC 133 N-Nitroso-N-propylamine Dipropylnitrosamine N-Nitrosodi-n-propylamine N-nitroso-n-propyl-1-propanamine 2-Oxo-1,1-dipropylhydrazine Di-N-propylnitrosamine Di-n-propylnitrosoamine Dipropylamine, N-nitroso- dipropyl-nitroso-amine DPNA n,n-di-n-propylnitrosamine N,N-Dipropylnitrosamine Nitrosodipropylamine n-nitroso-dipropylamin n-nitroso-n-di-propylamin n-nitroso-n-propyl-1-propanamin n-nitroso-n-propyl-propanamin N-Propanamine,N-propyl-N-nitroso- Propanamine, N-nitroso-N-propyl- Propylamine, N-nitroso-N-di- Rcra waste number U111 rcrawastenumberu111 N-Nitroso-n-propyl-1-propanamine N-NITROSODI-N-PROPYLAMINE N-NITROSODIPROPYLAMINE DIPROPYLNITROSAMINE nitrous dipropylamide N-Nitrosodi-N-propylamine? N-nitrosodipropylamine N-nitroso-N-dipropylamine N-NITROSODI-N-PROPYLAMINE, 100MG, NEAT N-NITROSODI-N-PROPYLAMINE, 1X1ML, MEOH 5 000UG/ML 1-Propanamine, N-nitorso-N-propyl- Di-n-prpylnitrosamine N-Nitrosodi-n-propylanime nitrosodipropylamin n-nitrosodi-n-propylamine solution N,N-Dipropyl-N-nitrosoamine Nitrosodi-n-propylamine N-Nitrosodi-n-propylamine@100 μg/mL in Dichloromethane N-Nitrosodi-n-propylamineSolution,5,000mg/L,1ml N-Nitrosodi-n-propylamineSolution,1,000mg/L,1ml N-Nitrosodi-n-propylamine @5.0 mg/mL in MeOH N-Nitrosodi-n-propylamineSolution,100mg/L,1ml N-Nitrosodi-n-propylamine@2.5 mg/mL in Dichloromethane N-Nitrosodipropylamine> N-Nitrosodi-n-propylamineSolution,1mg/L,25ml 1-Propanamine, N-nitroso-N-propyl- N-Nitroso-di-n-propylamine Solution in Methanol, 100μg/mL N-Nitrosodipropylamine (1mg/1ml) 621-64-7 C3H72NNO Aliphatics Miscellaneous Reagents Nitrosamine AliphaticsVolatiles/ Semivolatiles Alpha Sort