O-Tolidine | 119-93-7

O-Tolidine Properties

Melting point	128-131 °C(lit.)
Boiling point	300.5 °C
Density	0.9678 (rough estimate)
refractive index	n20/D 1.341
Flash point	244 °C
storage temp.	-20°C
solubility	2% HCl: 10 mg/mL, clear
form	powder (may contain lumps)
pka	4.59±0.10(Predicted)
Colour Index	37230
color	light brown
Water Solubility	Slightly soluble in water.
Merck	14,9514
BRN	2210640
Exposure limits	TLV-TWA none; carcinogenicity: A2 — Suspected Human Carcinogen (ACGIH), Animal Limited Evidence (IARC).
InChIKey	NUIURNJTPRWVAP-UHFFFAOYSA-N
EWG's Food Scores	5
FDA UNII	63HLO2IV6K
Proposition 65 List	3,3'-Dimethylbenzidine (ortho-Tolidine)
NIST Chemistry Reference	[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethyl-(119-93-7)
IARC	2B (Vol. 1, Sup 7) 1987
EPA Substance Registry System	3,3'-Dimethylbenzidine (119-93-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08,GHS09

Signal word

Danger

Hazard statements

H302-H350-H411

Precautionary statements

P202-P264-P270-P273-P301+P312-P308+P313

Hazard Codes

T,N,F

Risk Statements

45-68-51/53-22-11

Safety Statements

53-45-61-16

RIDADR

UN 3082 9/PG 3

WGK Germany

3

RTECS

DD1225000

F

8

TSCA

Yes

HazardClass

6.1(b)

PackingGroup

III

HS Code

29215900

Toxicity

dog,LDLo,oral,600mg/kg (600mg/kg),Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 58, Pg. 167, 1907.

NFPA 704

	1
2		0

O-Tolidine price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T8533	o-Tolidine ≥97%, powder	119-93-7	25g	$94.6	2024-03-01	Buy
Sigma-Aldrich	31659	o-Tolidine analytical standard	119-93-7	100mg	$62	2024-03-01	Buy
TCI Chemical	T0253	o-Tolidine min. 98.0 %	119-93-7	1G	$68	2024-03-01	Buy
TCI Chemical	T0253	o-Tolidine min. 98.0 %	119-93-7	5G	$237	2024-03-01	Buy
TCI Chemical	T0253	o-Tolidine >98.0%(GC)	119-93-7	25g	$39	2021-12-16	Buy

Product number	Packaging	Price	Buy
T8533	25g	$94.6	Buy
31659	100mg	$62	Buy
T0253	1G	$68	Buy
T0253	5G	$237	Buy
T0253	25g	$39	Buy

O-Tolidine Chemical Properties,Uses,Production

Description

o-Tolidine, also called orthotolidine or 2-tolidine, is a chemical compound with the molecular formula (C6H4(CH3)NH2)2. It is a white to reddish-colored, combustible, aromatic amine that emits toxic fumes of nitrogen oxides when heated to decomposition. Several isomers are known; the 3-tolidine derivative is also important commercially. It is a colorless compound although commercial samples are often colored. It is slightly soluble in water. It forms salts with acids, such as hydrochloride, which is commercially available. 2-Tolidine can be produced by a benzidine rearrangement from a hydrazine derivative derived from 2-nitrotoluene.

Chemical Properties

o-Tolidine is a white to reddish crystal or powder and has an aniline-like odor. It is soluble in alcohol, ether, and dilute acid, but only slightly soluble in water. It has a tendency to darken when exposed to air and is commonly utilized in paste or wet cake form. This compound serves as a fundamental component for the production of numerous dyes.

Uses

o-Tolidine is used extensively in the manufacture of dyes, especially in the production of soluble azo dyes and insoluble pigments for the textile, leather, and paper sectors. Additionally, It is also used as a sensitive colorimetric reagent for the analysis of gold and free chlorine in water.

Uses

3,3'-Dimethylbenzidine be used for preparation polyimide and epoxy resin material.

Preparation

There are two commonly used methods for producing o-Tolidine. The first method involves reducing ortho-nitrotoluene to 1,2-diorthotolylhydrazine, which is then rearranged with acid. The second method involves reducing o-nitrotoluene using zinc dust and caustic soda, then converting the resulting hydrazotoluene to o-Tolidine by boiling it with hydrochloric acid. Once either of these methods is completed, o-Tolidine can be extracted and purified through techniques such as solvent extraction and recrystallization.

Definition

ChEBI: 3,3'-Dimethylbenzidine is a member of biphenyls.

General Description

3,3'-dimethylbenzidine appears as white to reddish crystals or crystalline powder or a light tan powder. (NTP, 1992)

Air & Water Reactions

Insoluble in water.

Reactivity Profile

C.I. 37230 is sensitive to exposure to light. May be sensitive to prolonged exposure to air. A weak base that forms salts with hydrochloric acid or sulfuric acid. C.I. 37230 can be acetylated. Incompatible with strong agents .

Hazard

Eye, bladder and kidney irritant, bladder cancer, and methemoglobinemia. Possible carcinogen.

Health Hazard

The information on toxicity and carcinogenicity of o-tolidine is very little. o-Tolidineoften contains other biphenylamine contaminants. Its structure and chemical propertiesare similar to those of benzidine. The toxicproperties are therefore expected to be similar to those of benzidine.
o-Tolidine is absorbed into body throughthe skin, respiratory, and gastrointestinaltract. The acute oral and dermal toxicity wasmoderate in experimental animals. An oralLD50 value in rats is within the range of400 mg/kg.
o-Tolidine produced bladder cancer in testspecies. Also, cancers in other tissues werenoted in some animals. ACGIH lists thissubstance as a suspected human carcinogen.

Fire Hazard

Flash point data for C.I. 37230 are not available; however, C.I. 37230 is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Potential Exposure

Over 75% of o-tolidine is used as a dye and as an intermediate in the production of rubber products, dyestuffs, pigments and pesticides. Approximately 20% of o-tolidine is used in the production of polyurethane-based high-strength elastomers, coatings, and rigid plastics. o-Tolidine has also been used in small quantities in chlorine test kits by water companies and swimming pool owners. Used as a laboratory agent to detect blood.

Carcinogenicity

3,3′-Dimethylbenzidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Dissolve the tolidine in *benzene by percolation through a column of activated alumina and crystallise it from *benzene/pet ether. [Beilstein 13 IV 410.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, strong reducing agents.

Waste Disposal

Dissolve in flammable solvent and spray into firebox of an incinera tor equipped with afterburner and scrubber. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

O-Tolidine Preparation Products And Raw materials

Raw materials

2-Nitrotoluene 6-Amino-4-hydroxy-2-naphthalenesulfonic acid O-Tolidine

Preparation Products

disodium 3-[[4'-[(6-amino-1-hydroxy-3-sulphonato-2-naphthyl)azo]-3,3'-dimethoxy[1,1'-biphenyl]-4-yl]azo]-4-hydroxynaphthalene-1-sulphonate DIRECT BLUE 15 N,N'-(3,3'-Dimethyl-4,4'-biphenyldiyl)bis(3-oxobutanamide) Sieber Linker ACID RED 114

5-Amino-4-hydroxy-3-[[4'-[(1-hydroxy-4-sulfonaphthalen-2-yl)azo]-3,3'-dimethyl[1,1'-biphenyl]-4-yl]azo]-2,7-naphthalenedisulfonic acid trisodium salt N,N'-(3,3'-Dimethyl-4,4'-biphenyldiyl)bis(3-oxobutanamide) 1,3,6-Naphthalenetrisulfonic acid, 8-hydroxy-7-[[4'-[(2-hydroxy-1-naphthalenyl)azo]-3,3'-dimethyl[1,1'-biphenyl]-4-yl]azo]-, trisodium salt BRILLIANT PURPURIN R trisodium 5-amino-3-[[4'-[(6-amino-1-hydroxy-3-sulphonato-2-naphthyl)azo]-3,3'-dimethyl[1,1'-biphenyl]-4-yl]azo]-4-hydroxynaphthalene-2,7-disulphonate

Direct Black 24 DIRECT ORANGE 6 Evans Blue N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(3-hydroxynaphthalene-2-carboxamide) Direct Black 154

Direct Brown 222 C.I. Direct Orange 31 OXAMINE BLUE 4R Direct Brown 146 DIRECT YELLOW 2

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O-Tolidine Suppliers

Global( 363)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Allgreen Chemical Co.,LTD	+86-37155567971 +86-13633837469	info@allgreenchem.com	China	5986	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15933	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd.	0431-80514535 13634302652	Extension@chemextension.com	CHINA	967	58
Cangzhou Wanyou New Material Technology Co.,Ltd	18631714998	sales@czwytech.com	CHINA	906	58

Supplier	Advantage
Henan Allgreen Chemical Co.,LTD	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd.	58
Cangzhou Wanyou New Material Technology Co.,Ltd	58

View Lastest Price from O-Tolidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-01-23	3,3'-Dimethyl-[1,1'-biphenyl]-4,4'-Diamine(O-Tolidine) 119-93-7	US $0.00 / KG	1KG	99%	1500KG/month	Shanghai Daken Advanced Materials Co.,Ltd
2023-11-29	O-Tolidine 119-93-7	US $0.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.
2023-09-06	O-Tolidine 119-93-7	US $30.00-10.00 / KG	50KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

3,3'-Dimethyl-[1,1'-biphenyl]-4,4'-Diamine(O-Tolidine)
119-93-7
US $0.00 / KG
99%
Shanghai Daken Advanced Materials Co.,Ltd

O-Tolidine
119-93-7
US $0.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

O-Tolidine
119-93-7
US $30.00-10.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

O-Tolidine Spectrum

O-Tolidine(119-93-7)MS O-Tolidine(119-93-7)¹HNMR O-Tolidine(119-93-7)¹³CNMR O-Tolidine(119-93-7)IR1 O-Tolidine(119-93-7)IR2 O-Tolidine(119-93-7)IR3

119-93-7(O-Tolidine)Related Search:

O-TOLIDINE SULFONE o-Toluidine O-TOLIDINE SULFONE DIRECT FAST RED 3B 3,3'-Dimethyl-4,4'-biphenylene diisocyanate

N-(3-Sulfopropyl)-3,3',5,5'-tetramethylbenzidine sodium salt 3,3'-Dimethylbenzidine dihydrochloride 4,4'-DIAMINOBIPHENYL-3,3'-DICARBOXYLIC ACID Trypan Blue 3,3'-DIMETHYLNAPHTHIDINE

BENZOPURPURIN 4B N,N'-(3,3'-Dimethyl-4,4'-biphenyldiyl)bis(3-oxobutanamide) Tetramethylbenzidine ACID RED 114 2,2'-Dimethyl-1,1'-biphenyl-4,4'-diamine dihydrochloride

m-Tolidine DIANIL BLUE 2R CI 23790

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3,3'-Dimethyl-[1,1'-biphenyl]-4,4'-Diamine(O-Tolidine) 1’-biphenyl)-4,4’-diamine,3,3’-dimethyl-( 1’-Biphenyl)-4,4’-diamine,3,3’-dimethyl-(1 1’-biphenyl)-4,4’-diamine-3,3’-dimethyl-( 1’-biphenyl]-4,4’-diamine,3,3’-dimethyl-[ 2-Tolidin 2-Tolidina 3,3’-dimethyl-4,4’-biphenyldiamine 3,3’-dimethylbenzidin 3,3’-dimethyl-benzidin 3,3’-dimethyldiphenyl-4,4’-diamine TIMTEC-BB SBB008947 O-TOLIDINE PRACTICAL GRADE O-TOLIDINE SOLUTION ACCORDING TO ELLMS-H AUSER O-TOLIDINE, TECH. 3,3-DIMETHYLBENZIDINE OEKANAL, 100 M O-TolidineGr O-TolidineGr-(3,3'-Dimethylbenzidine) 3,3^'-dimethylbenzidine 3 3,3-Tolidine 1,1-Biphenyl-4,4-diamine, 3,3-dimethyl- o-tolidine solution O-TOLIDINE,POWDER,REAGENT 3,3''-DIMETHYL-4,4''-DIAMINOBIPHENYL OR O-TOLIDINE 4,4 -Bi-o-toulidin o-TOLIDINE (3,3-Dimethyl Benzidine) extrapure AR o-Tolidine, pract, 95% PATENT BLUE VF ULTRA PURE GRADE 3,3'-dimethyl-4,4'-diaminobiphenyl(o-tolidine) 3,3'-Dimethyl-4,4'-biphenyldiamine 3,3'-Dimethylbenzidin 3,3'-Dimethyldiphenyl-4,4'-diamine 4,4’-diamino-3,3’-dimethyldiphenyl 4,4’-di-o-toluidine 4,4'-Diamino-3,3'-dimethyldiphenyl 4,4'-Di-o-toluidine 4'-Amino-3,3'-dimethyl[1,1'-biphenyl]-4-ylamine Benzidine, 3,3'-dimethyl- bianisidine C.I. Azoic Diazo Component 113 c.i.azoicdiazocomponent113 ciazoicdiazocomponent113 Diaminoditolyl diaminotolyl di-o-toluidine o,o’-tolidine o,o'-Tolidine o-Tolidin Rcra waste number U095 rcrawastenumberu095 ORTHO-TOLIDINE REAGENT O-TOLIDINE O-TOLIDINE REAGENT tolidine(non-specificname) 3,3'-TOLIDINE 3,3'-DIMETHYL-4,4'-DIPHENYLDIAMINE 3,3'-DIMETHYL-4,4'-DIAMINOBIPHENYL 3,3'-DIMETHYL-[1,1'-BIPHENYL]-4,4'-DIAMINE