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Cynarin structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

Cynarin Properties

Melting point:
D25 -59° (c = 2 in methanol)
Boiling point:
819.9±65.0 °C(Predicted)
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
methanol: soluble5mg/mL, clear, light yellow to yellow
faint yellow to yellow
CAS DataBase Reference
30964-13-7(CAS DataBase Reference)
  • Risk and Safety Statements
Safety Statements  24/25
WGK Germany  3
HS Code  29182900

Cynarin price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 91801 Cynarin analytical standard 30964-13-7 5mg $398 2021-03-22 Buy
Cayman Chemical 25022 1,3-Dicaffeoylquinic Acid ≥98% 30964-13-7 5mg $95 2021-03-22 Buy
Cayman Chemical 25022 1,3-Dicaffeoylquinic Acid ≥98% 30964-13-7 10mg $135 2021-03-22 Buy
Cayman Chemical 25022 1,3-Dicaffeoylquinic Acid ≥98% 30964-13-7 25mg $309 2021-03-22 Buy
Cayman Chemical 25022 1,3-Dicaffeoylquinic Acid ≥98% 30964-13-7 50mg $570 2021-03-22 Buy

Cynarin Chemical Properties,Uses,Production



Manufacturing Process

18.0 g of caffeic acid, suspended in 500 ml of water, are dissolved by adding sodium bicarbonate and stirring. The solution is cooled to 2°-3°C and then, while stirring continuously, 20.0 g of phosgene dissolved in 200 ml of chloroform are added in 4 to 5 portions. After acidifying by cautiously adding iced hydrochloric acid (1:1), the solution is filtered and the collected precipitate is washed with water. Upon crystallization from glacial acetic acid, the carbonylcaffeic acid thus obtained melts at 238°-240°C (dec.).
5.0 g of carbonylcaffeic acid are suspended in 70 ml of ligroin (b. p. 120°- 140°C). After adding 6.0 g of phosphorus pentachloride and avoiding access of moisture while frequently stirring, the suspension is refluxed by boiling slowly and gently until everything is dissolved except a small amount of reddish, resinous materials that adhere to the bottom. Then solution is rapidly decanted into another flask containing 1.0 g of phosphorus pentachloride and the whole is refluxed gently for about 15-30 min, after which time evolution of hydrochloric acid ceases. This solution is left to cool on air for 1-2 h, and then, the obtained carbonylcaffeic acid chloride rapidly is filtered, washed with low-boiling ligroin and dried under vacuum at room temperature for about 1- 1.5 h. Melting point 118°-120°C.
5.0 g of carbonylcaffeic acid chloride are thoroughly mixed with 12.8 g of dry, powdered quinide in a flask immersed in an oil bath. The flask is put under vacuum and is heated to 120°C and then, slowly, to about 160°C, maintaining this temperature for about 20-30 min. The molten mass is left to cool under vacuum and then it is crushed in a mortar in the presence of water. This material is washed with water several times. The residue is dissolved in dioxin. 400 ml of cold, 3% barium hydroxide solution are added and cooled with ice water and stirring vigorously in nitrogen atmosphere. The solution is left standing insulated from contact with air for 20 h, whereupon the content is rapidly acidified and concentrated in vacuum, on a water bath, to a volume of about 80-100 ml. After cooling and standing, well protected from contact with air, the brown material is filtered off and purified by crystallization from 50% acetic acid. 1,4-Dicaffeylquinic acid is obtained, melting point 226°- 228°C.

Therapeutic Function

Choleretic, Antihyperlipidemic

Cynarin Preparation Products And Raw materials

Raw materials

Preparation Products

Cynarin Suppliers

Global( 187)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Standard Technology Co., Ltd.
+86-21-57127007-6606 CHINA 1923 58
Hangzhou FandaChem Co.,Ltd.
+86-571-56059825 CHINA 8882 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3623 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253 CHINA 1257 58
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086 CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897 CHINA 2712 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 China 5450 58
Xi'an Kono chem co., Ltd.,
13289246953 029-86107037 CHINA 3000 58

View Lastest Price from Cynarin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-20 hot selling Cynarin
US $216.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biological Technology Co., Ltd
2021-09-07 Anti-Hyperlipidemia 5% Cynarin Artichoke Extract
US $20.00 / Kg/Drum 25Kg/Drum 99.99% 1 ton per week Wuhan Mulei New Material Technology Co. Ltd
2021-01-15 Anti-Hyperlipidemia 5% Cynarin Artichoke Extract
US $1.00 / PCS 1PCS 99% 100mt Hebei Guanlang Biotechnology Co., Ltd.

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