AICAR (phosphate)
- CAS No.
- 681006-28-0
- Chemical Name:
- AICAR (phosphate)
- Synonyms
- AICAR (phosphate);Acadesine phosphate;AICAR phosphate, >98%;AICA Riboside phosphate);AICAR (Acadesine) phosphate;AICA-riboside monophosphate;AICAR phosphate (Acadesine phosphate;ACADESINE PHOSPHATE;AICA RIBOSIDE PHOSPHATE;5-Amino-1-ribosylimidazole-4-carboxamide phosphate
- CBNumber:
- CB82677075
- Molecular Formula:
- C9H17N4O9P
- Molecular Weight:
- 356.23
- MDL Number:
- MFCD23726600
- MOL File:
- 681006-28-0.mol
AICAR (phosphate) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B1211 | AICARphosphate | 681006-28-0 | 50mg | $40 | 2021-12-16 | Buy |
| ApexBio Technology | B1211 | AICARphosphate | 681006-28-0 | 200mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-1952 | AICAR(phosphate) 99.49% | 681006-28-0 | 500mg | $336 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611683 | AICAR phosphate | 681006-28-0 | 250mg | $345.1 | 2021-12-16 | Buy |
| ApexBio Technology | B1211 | AICARphosphate | 681006-28-0 | 1g | $350 | 2021-12-16 | Buy |
AICAR (phosphate) Chemical Properties,Uses,Production
Biological Activity
aicar phosphate （acadesine）is an activator of ampk [1].aicar phosphate has been reported to induce apoptosis in a dose-dependent fashion and that the ec50 value is 380±60μm on the viability assay of b-cll cells. in addition, aicar phosphate has been revealed to induce caspase activation and cytochrome c release from mitochondria in b-cll cells. furthermore, aicar phosphate has shown that uptake and phosphorylation are required to induce apoptosis and activate ampk. apart from these, aicar phosphate (2-4 mm) has shown to only slightly affects the viability of t cells from b-cll patients, aicar phosphate (0.5 mm) has been noted to remarkedly reduces viability of b cells but not t cells [1].
References
[1] campàs c1, lopez jm, santidrián af, barragán m, bellosillo b, colomer d, gil j. acadesine activates ampk and induces apoptosis in b-cell chronic lymphocytic leukemia cells but not in t lymphocytes. blood. 2003 may 1;101(9):3674-80. epub 2003 jan 9.
AICAR (phosphate) Preparation Products And Raw materials
Raw materials
Preparation Products
AICAR (phosphate) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |