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(1S,2R,3R)-Aprepitant

(1S,2R,3R)-Aprepitant structure

CAS No.: 1242175-34-3

Chemical Name:: (1S,2R,3R)-Aprepitant

Synonyms: Aprepitant Impurity 7;Aprepitant impurity 05;Aprepitant iMpurity 31;(2R,3R,1’S)-Aprepitant;Aprepitant (S,R,R)-Isomer;Aprepitant Impurity 4(S,R,R-Isomer);Aprepitant impurity 8/(1S,2R,3R)-Aprepitant;5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

CBNumber:: CB83146509

Molecular Formula:: C23H21F7N4O3

Molecular Weight:: 534.43

MDL Number:

MOL File:: 1242175-34-3.mol

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(1S,2R,3R)-Aprepitant Properties

Density	1.51±0.1 g/cm3(Predicted)
pka	8.06±0.20(Predicted)

(1S,2R,3R)-Aprepitant price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A729765	(2R,3R,1’S)-Aprepitant	1242175-34-3	1mg	$130	2021-12-16	Buy

Product number	Packaging	Price	Buy
A729765	1mg	$130	Buy

(1S,2R,3R)-Aprepitant Chemical Properties,Uses,Production

Uses

(2R,3R,1’S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(1S,2R,3R)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

(1S,2R,3R)-Aprepitant Suppliers

Global( 40)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
CR Corporation Lomited		fred.wen@crcorporation.cn	CHINA	12069	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Adamas Reagent, Ltd.	400-6009262 16621234537	zhangsn@titansci.com	China	14113	59
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Nanjing XiZe Biotechnology CO., Ltd.	025-58362220 15250997978	1511893459@qq.com	China	7715	55
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@qq.com	China	7851	55

Supplier	Advantage
Standardpharm Co. Ltd.	58
BOC Sciences	58
Hubei Ipure Biology Co., Ltd	58
CR Corporation Lomited	58
China National Standard Pharmaceutical Corporation Limited	58
Adamas Reagent, Ltd.	59
ChemStrong Scientific Co.,Ltd	56
Nanjing XiZe Biotechnology CO., Ltd.	55
BOC Sciences	65
Hubei Yangxin Medical Technology Co., Ltd.	55

1242175-34-3((1S,2R,3R)-Aprepitant)Related Search:

(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Aprepitant Fosaprepitant dimeglumine (R,R,R)-Aprepitant

5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Fosaprepitant Impurity 6 1,1,1-Trimethoxy-2-chloroethane Fosaprepitant Impurity 5 Fosaprepitant

(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Aprepitant Impurity 9 Aprepitant Defluoro Aprepitant Aprepitant Impurity B HCl

5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

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Aprepitant Impurity 7 5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one Aprepitant (S,R,R)-Isomer (2R,3R,1’S)-Aprepitant Aprepitant iMpurity 31 Aprepitant Impurity 4(S,R,R-Isomer) Aprepitant impurity 8/(1S,2R,3R)-Aprepitant 5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one 3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro- Aprepitant impurity 05 1242175-34-3