5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
- CAS No.
- 124750-51-2
- Chemical Name:
- 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
- Synonyms
- Losaint-B;ALSTint-A04;Valsartan IMP;Valsartan Impurity;Valsartan Impurity 8;Valsartan Impurity 9;TRITYLATED BROMO IMP;Valsartan impurity 19;Fimasartan Impurity B;Valsartan intermediate
- CBNumber:
- CB8369024
- Molecular Formula:
- C33H25BrN4
- Molecular Weight:
- 557.48
- MDL Number:
- MFCD00665221
- MOL File:
- 124750-51-2.mol
Melting point | 152-155°C |
---|---|
Boiling point | 61°C/12mmHg(lit.) |
Density | 1.28±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | Soluble in Chloroform and Methanol (Sparingly) |
form | Solid |
pka | 0.29±0.10(Predicted) |
color | White |
Stability | Moisture Sensitive |
InChI | InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2 |
InChIKey | ZTFVTXDWDFIQEU-UHFFFAOYSA-N |
SMILES | N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1 |
CAS DataBase Reference | 124750-51-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS07 |
---|---|
Signal word | Danger |
Hazard statements | H315-H319-H228 |
Precautionary statements | P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
RIDADR | UN 2811 6.1/PG III |
HazardClass | 6.1 |
PackingGroup | III |
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | T137073 | 5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-1H-TETRAAZOLE Aldrich | 124750-51-2 | 10mg | $139 | 2024-03-01 | Buy |
Biosynth Carbosynth | FB19245 | 5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole | 124750-51-2 | 50g | $150 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19245 | 5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole | 124750-51-2 | 100g | $240 | 2021-12-16 | Buy |
AK Scientific | J11478 | OlmesartanImpurity20 | 124750-51-2 | 100mg | $95 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19245 | 5-[4'-Bromomethyl-(1,1'-biphenyl)-2-yl]-1-triphenylmethyltetrazole | 124750-51-2 | 25g | $100 | 2021-12-16 | Buy |
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Chemical Properties,Uses,Production
Description
5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole is an intermediate in the synthesis of Losartan and Valsartan. Utilized for various purposes, 5-[4′-Bromomethyl-(1,1′-biphenyl)-2-yl]-1-triphenylmethyltetrazole has found application as a fluorescent probe to identify DNA damage. It serves as a photosensitizer in photodynamic therapy and acts as a catalyst in polymer synthesis. Furthermore, this compound functions as a fluorescent label to detect proteins and as a fluorescent indicator to detect metal ions.
Chemical Properties
Off-White Solid
Uses
Used as Olmesartan medoxomil related intermediate, Olmesartan medoxomil is an angiotensin II receptor antagonist[1].
Application
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole is an important pharmaceutical intermediate. It can be used in the preparation of olmesartan medoxomil key intermediates, Losartan potassium, Valsartan, Candesartan and molecular sieve catalysts.
Hazard
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole has an acute toxin and is irritating to skin and eyes.
References
[1] HAI Z. Determination of the related substances in N-triphenylmethyl-5-(4’-bromomethylbiphenyl-2-yl-) terazole by HPLC[J]. West China Journal of Pharmaceutical Sciences, 2015.
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sinopharm International Guangzhou Ltd. | +86-2038033341 +86-18520036739 | zhuluqiang@sinopharm.com | China | 77 | 58 |
JUYE XIANDAI fine chemistry Co.,Ltd | +8618958038633 | tony@sdhypharma.com | China | 61 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
Hebei Dangtong Import and export Co LTD | +8615632927689 | admin@hbdangtong.com | China | 986 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | forrest.lee@dakenchem.com | China | 15956 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
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- N-(triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl)tetrazolium, is a chemical substance with the molecular formula C33H25BrN4,....
- Sep 6,2022
View Lastest Price from 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-17 | 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
124750-51-2
|
US $36.00-27.00 / kg | 1kg | 99% | 5000kg | Hebei Dangtong Import and export Co LTD | ||
2024-05-08 | BBTT
124750-51-2
|
US $0.00 / KG | 2KG | 99% up, High Density | 20 tons | Sinoway Industrial co., ltd. | ||
2023-11-01 | 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
124750-51-2
|
US $0.00-0.00 / kg | 1kg | 99.0%min | 10tons | Hangzhou ICH Biofarm Co., Ltd |
- 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
124750-51-2
- US $36.00-27.00 / kg
- 99%
- Hebei Dangtong Import and export Co LTD
- BBTT
124750-51-2
- US $0.00 / KG
- 99% up, High Density
- Sinoway Industrial co., ltd.
- 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
124750-51-2
- US $0.00-0.00 / kg
- 99.0%min
- Hangzhou ICH Biofarm Co., Ltd
124750-51-2(5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole)Related Search:
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