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2'-Hydroxyacetophenone

Description Reference
2'-Hydroxyacetophenone
2'-Hydroxyacetophenone structure
CAS No.
118-93-4
Chemical Name:
2'-Hydroxyacetophenone
Synonyms
usafke-20;FEMA 3548;AKOS 90575;USAF ke-20;2-ACETOPHENOL;O-ACETOPHENOL;2-ACETYLPHENOL;o-Acetylphenol;BENZOYLCARNINOL;AKOS BBS-00003239
CBNumber:
CB8421762
Molecular Formula:
C8H8O2
Formula Weight:
136.15
MOL File:
118-93-4.mol

2'-Hydroxyacetophenone Properties

Melting point:
3-6 °C(lit.)
Boiling point:
213 °C717 mm Hg(lit.)
Density 
1.131 g/mL at 25 °C(lit.)
vapor density 
4.7 (vs air)
vapor pressure 
~0.2 mm Hg ( 20 °C)
refractive index 
n20/D 1.558(lit.)
FEMA 
3548 | 2-HYDROXYACETOPHENONE
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
0.2g/l
form 
Liquid
pka
10.06(at 25℃)
color 
Clear yellow to brown
explosive limit
0.98-11.8%(V)
Water Solubility 
slightly soluble
JECFA Number
727
BRN 
386123
CAS DataBase Reference
118-93-4(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
2-HYDROXYACETOPHENONE
EWG's Food Scores
1
FDA UNII
3E533Z76W0
NIST Chemistry Reference
Ethanone, 1-(2-hydroxyphenyl)-(118-93-4)
EPA Substance Registry System
2'-Hydroxyacetophenone (118-93-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-36/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  AM8575000
8
Hazard Note  Harmful/Irritant
TSCA  Yes
HS Code  29145000
Toxicity LD50 orally in Rabbit: 2127 mg/kg LD50 dermal Rat > 2000 mg/kg
NFPA 704
1
2 0

2'-Hydroxyacetophenone price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H18607 2′-Hydroxyacetophenone ReagentPlus , 99% 118-93-4 5g $20.3 2019-12-02 Buy
Sigma-Aldrich 18245 2′-Hydroxyacetophenone analytical standard 118-93-4 1ml $60.5 2019-12-02 Buy
TCI Chemical H0192 2'-Hydroxyacetophenone >98.0%(HPLC)(T) 118-93-4 25g $16 2020-06-24 Buy
TCI Chemical H0192 2'-Hydroxyacetophenone >98.0%(HPLC)(T) 118-93-4 100g $34 2020-06-24 Buy
Alfa Aesar A12550 2'-Hydroxyacetophenone, 98% 118-93-4 100g $21.5 2020-06-24 Buy

2'-Hydroxyacetophenone Chemical Properties,Uses,Production

Description

It is a typical flavour additive for cherry kernel, cinnamon, rum, tobacco, coumarin, and tropical fruit. Moreover, it can be used as the intermediate or raw material in organic synthesis. Specifically, this chemical may act as the raw material to prepare a Schiff’s base al-alkoxide initiator that facilitates the controlled polymerization of DL-lactide.1 This substance can also function as the effective component in balsamic compounds for fabricating taste modifying compositions.2 Additionally, this chemical has been employed to react with benzoyl chloride for generating 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran, which exhibits good performance for treating cancer and other proliferative diseases such as psoriasis and restenosis.3

Reference

  1. Bhaw-Luximon, A.; Jhurry, D.; Spassky, N., Controlled polymerization of DL-lactide using a Schiff's base al-alkoxide initiator derived from 2-hydroxyacetophenone. Polym. Bull. 2000, 44, 31-38.
  2. Johann Wonschick; Clemens M. Putter; Keepe, E., TASTE MODIFYING COMPOSITIONS PCT WO 2016/103183 A1 2016.
  3. Alexander J Bridges; Saltiel, A. R., 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders US Patent US5525625 1996.

Chemical Properties

clear yellow to brown liquid

Chemical Properties

2-Hydroxyacetophenone has a sweet, heavy floral, herbaceous odor, reminiscent of mown hay or hawthorn

Occurrence

Reported found in beef, cassia oil, cocoa, cocoa powder, coffee, Jamaican rum, tomato, Scotch whiskey, sherry, tea, mountain papaya, papaya, roasted almond and black choke berry

Uses

2’Hydroxyacetophenone is a phenolic compound used in the synthesis of potential anti-myobacterial and anticancer agents.

Preparation

Preparation by Fries rearrangement of phenyl acetate, with Lewis acids
aluminium chloride.

Aroma threshold values

Detection: 5.5 ppm; aroma characteristics at 2.0%: phenolic, sharp, benzaldehyde, cherry pit, tropical, melon with a tobacco afternote

Taste threshold values

Taste characteristics at 5.0 ppm: naphthyl, cinnamon, cherry pit, coumarin, phenolic, tobacco and honey.

2'-Hydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products


2'-Hydroxyacetophenone Suppliers

Global( 407)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 19929 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21836 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2680 55
Tianjin Zhongxin Chemtech Co., Ltd.
022-66880623
022-66880086 sales@tjzxchem.com CHINA 602 58
Hebei Chishuo Biotechnology Co., Ltd.
13292891350 +86 311 66567340
luna@speedgainpharma.com CHINA 1009 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30043 58
Hebei Huanhao Biotechnology Co., Ltd.
+8618034552304
86-0311-83975816 cathylee@hbhuanhao.com CHINA 871 58

View Lastest Price from 2'-Hydroxyacetophenone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-04-16 2'-Hydroxyacetophenone
118-93-4
US $200.00 / 公斤 1公斤 99.99% 20tons Hebei Huanhao Biotechnology Co., Ltd.
2019-12-04 2'-Hydroxyacetophenone +8619930503283
118-93-4
US $10.00 / KG 1KG 98%min 20tons Hebei Guanlang Biotechnology Co., Ltd.
2020-04-15 2'-Hydroxyacetophenone
118-93-4
US $60.00 / g 10g 99.8% 10tons Hebei shuoxi biotechnology co. LTD

2'-Hydroxyacetophenone Spectrum


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