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2'-Hydroxyacetophenone

Description Reference
2'-Hydroxyacetophenone
2'-Hydroxyacetophenone structure
CAS No.
118-93-4
Chemical Name:
2'-Hydroxyacetophenone
Synonyms
usafke-20;FEMA 3548;USAF ke-20;AKOS 90575;2-ACETOPHENOL;O-ACETOPHENOL;o-Acetylphenol;2-ACETYLPHENOL;BENZOYLCARNINOL;AKOS BBS-00003239
CBNumber:
CB8421762
Molecular Formula:
C8H8O2
Formula Weight:
136.15
MOL File:
118-93-4.mol

2'-Hydroxyacetophenone Properties

Melting point:
3-6 °C(lit.)
Boiling point:
213 °C717 mm Hg(lit.)
Density 
1.131 g/mL at 25 °C(lit.)
vapor density 
4.7 (vs air)
vapor pressure 
~0.2 mm Hg ( 20 °C)
refractive index 
n20/D 1.558(lit.)
FEMA 
3548 | 2-HYDROXYACETOPHENONE
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
0.2g/l
form 
Liquid
pka
10.06(at 25℃)
color 
Clear yellow to brown
explosive limit
0.98-11.8%(V)
Water Solubility 
slightly soluble
JECFA Number
727
BRN 
386123
CAS DataBase Reference
118-93-4(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2-hydroxyphenyl)-(118-93-4)
EPA Substance Registry System
Ethanone, 1-(2-hydroxyphenyl)-(118-93-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38-36/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  AM8575000
8
Hazard Note  Harmful/Irritant
TSCA  Yes
HS Code  29145000
Toxicity LD50 orally in Rabbit: 2127 mg/kg LD50 dermal Rat > 2000 mg/kg
Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

2'-Hydroxyacetophenone price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H18607 2′-Hydroxyacetophenone ReagentPlus , 99% 118-93-4 5g $20 2018-11-13 Buy
Sigma-Aldrich 18245 2′-Hydroxyacetophenone analytical standard 118-93-4 1ml $59.2 2018-11-13 Buy
TCI Chemical H0192 2'-Hydroxyacetophenone >98.0%(HPLC)(T) 118-93-4 25g $17 2018-11-22 Buy
TCI Chemical H0192 2'-Hydroxyacetophenone >98.0%(HPLC)(T) 118-93-4 100g $36 2018-11-22 Buy
Alfa Aesar A12550 2'-Hydroxyacetophenone, 98% 118-93-4 100g $20 2018-11-15 Buy

2'-Hydroxyacetophenone Chemical Properties,Uses,Production

Description

It is a typical flavour additive for cherry kernel, cinnamon, rum, tobacco, coumarin, and tropical fruit. Moreover, it can be used as the intermediate or raw material in organic synthesis. Specifically, this chemical may act as the raw material to prepare a Schiff’s base al-alkoxide initiator that facilitates the controlled polymerization of DL-lactide.1 This substance can also function as the effective component in balsamic compounds for fabricating taste modifying compositions.2 Additionally, this chemical has been employed to react with benzoyl chloride for generating 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran, which exhibits good performance for treating cancer and other proliferative diseases such as psoriasis and restenosis.3

Reference

  1. Bhaw-Luximon, A.; Jhurry, D.; Spassky, N., Controlled polymerization of DL-lactide using a Schiff's base al-alkoxide initiator derived from 2-hydroxyacetophenone. Polym. Bull. 2000, 44, 31-38.
  2. Johann Wonschick; Clemens M. Putter; Keepe, E., TASTE MODIFYING COMPOSITIONS PCT WO 2016/103183 A1 2016.
  3. Alexander J Bridges; Saltiel, A. R., 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders US Patent US5525625 1996.

Chemical Properties

clear yellow to brown liquid

Uses

2’Hydroxyacetophenone is a phenolic compound used in the synthesis of potential anti-myobacterial and anticancer agents.

2'-Hydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products


2'-Hydroxyacetophenone Suppliers

Global( 341)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21954 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Tianjin Zhongxin Chemtech Co., Ltd.
022-89880739
022-66880086 sales@tjzxchem.com CHINA 558 58
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58

View Lastest Price from 2'-Hydroxyacetophenone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-17 2'-Hydroxyacetophenone
118-93-4
US $7.00 / kg 1kg 99% 100KG career henan chemical co
2018-12-17 2'-Hydroxyacetophenone
118-93-4
US $7.00 / kg 1kg 99% 100KG career henan chemical co

2'-Hydroxyacetophenone Spectrum


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