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Chemical Name:
hn3;HsN3;ts160;tl145;TS 160;PROS26;A 8729;TL 145;agenthn3;ai3-16198
Molecular Formula:
Formula Weight:
MOL File:


Melting point:
Boiling point:
bp15 144°
d425 1.2347
refractive index 
nD25 1.4925
storage temp. 


RIDADR  2810
HazardClass  6.1(a)
PackingGroup  I


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TRIS-(2-CHLOROETHYL)-AMINE Chemical Properties,Uses,Production


Nitrogen mustards are very potential chemical substances of yesteryears and produced during the 1920s and 1930s as chemical warfare weapons. They are vesicants (or blister agents) similar to the sulphur mustards. They smell fishy, musty, soapy, or fruity and are either in the form of an oily textured liquid or a vapour (the gaseous form of a liquid) or a solid. It is in liquid form at normal room temperature (70 F) with a clear, pale amber, or yellow colour. HN-1, HN-2, and HN-3 are the military designations of nitrogen mustard (for more data, refer to Muatars gas). Nitrogen mustards (HN-1, HN-2, HN-3) are colourless to yellow, oily liquids that evaporate very slowly. HN-1 has a faint fishy or musty odour. HN-2 has a soapy odour at low concentrations and a fruity odour at higher concentrations. HN-3 may smell like butter almond. Use of nitrogen mustards is very much restricted other than for chemical warfare. In fact, presently, its use has no records. HN-1 has been used to remove warts in the past, and HN-2 has been used sparingly in chemotherapy.

Chemical Properties

HN-3, a nitrogen mustard blister agent (vesicants, is a colorless to pale yellow liquid. Pure material is odorless; otherwise, it has a faint fish-or soap-like odor.

General Description

Liquid with faint odor of fish and soap, no odor when pure. Used as a delayed-action casualty military agent.

Air & Water Reactions

Acts as a strong base in water.

Reactivity Profile

When dissolved in water, TRIS-(2-CHLOROETHYL)-AMINE is a strong base; reacts violently with strong oxidants and acids ; attacks copper and copper compounds. [Handling Chemicals Safely 1980. p. 123]; reacts with hypochlorites to give N-chloroamines, some of which are explosives when isolated [Bretherick 1979. p. 108].

Health Hazard

Most toxic of the nitrogen mustards. The median lethal dose for inhalation is 1,500 mg-min/m3; for skin absorption (masked personnel) is 10,000 mg-min/m3. The medium incapacitating dose for eye injury is 200 mg-min/m3; for skin absorption is 2,500 mg-min/m3.

Fire Hazard

When heated to decomposition, TRIS-(2-CHLOROETHYL)-AMINE emits chloride and nitrogen oxides. No action on metals or other materials if material is kept dry. Avoid decomposing heat.

Potential Exposure

Trichlorotriethylamine is a (slowacting) vesicant but has never been used in military conflict. Is used as an antineoplastic agent. Has been tested as a fixing agent in textile dyes.

First aid

There is no antidote for nitrogen mustard toxicity. Because health effects due to nitrogen mustard may not occur until several hours after exposure, patients/victims should be observed in a hospital setting for at least 24 hours. Gastric lavage is contraindicated following ingestion of this agent due to the risk of perforation of the esophagus or upper airway. If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Speed in removing material from skin is of extreme importance. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Keep victim quiet and maintain normal body temperature. Effects may be delayed; keep victim under observation.


UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver of HN-3 shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.


HN-3 is not stable; it undergoes slow but steady polymerization. Avoid contamination with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, bleaches and pool chemicalsetc); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Unstable in the presence of light and heat and forms dimers at temperatures above 50℃. HN-3 decomposes before its boiling point is reached or condenses under all conditions; the reactions involved could generate enough heat to cause an explosion. Polymerizes slowly, so munitions would be effective for several years. Heated to decomposition emits hydrogen chloride and nitrogen oxide. Note: Chlorinating agents destroy nitrogen mustards. Dry chlorinated lime and chloramines with a high content of active chlorine vigorously chlorinate nitrogen mustards to the carbon chain giving low toxicity products. In the presence of water this interaction proceeds less actively. They are rapidly oxidized by peracids in aqueous solution at weakly alkaline pH. In acid solution the oxidation is much slower.

TRIS-(2-CHLOROETHYL)-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products


Global( 13)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
BOC Sciences United States 10563 65
MedChemexpress LLC 609-228-6898
609-228-5909 United States 4621 58
JW & Y Pharmlab Co., Ltd. +86 (21) 6434-0559 or (215) 945-6595
+86 (21) 6434-5308 or (215) 945-6597;; China 15961 58
Musechem +1-800-259-7612
+1-800-259-7612 United States 4678 60

555-77-1(TRIS-(2-CHLOROETHYL)-AMINE)Related Search:

  • TS 160
  • ts160
  • AURORA KA-7833
  • 2,2',2''-Trichloroetylamine
  • Nitrogen Lost
  • HsN3
  • PROS26
  • 2-chloro-n,n-bis(2-chloroethyl)-ethanamin
  • 2-Chloro-N,N-bis(2-chloroethyl)ethanamine
  • A 8729
  • agenthn3
  • ai3-16198
  • Ethanamine, 2-chloro-N,N-bis(2-chloroethyl)-
  • hn3
  • NSC-260424
  • Sinalost base
  • 555-77-1
  • C6H12Cl3N
  • TL 145
  • tl145
  • tri-(2-chloroethyl)amine
  • Tri-2-chloroethylamine
  • Trichlormethine
  • Triethylamine, 2,2',2''-trichloro-
  • Trimitan base
  • Tris(b-chloroethyl)amine
  • Tris(beta-chloroethyl)amine
  • 2,2',2''-Trichlorotriethylamine
  • 2,2',2-Trichlorotriethylamine
  • 2,2’,2"-trichloro-triethylamin
  • 2,2’,2"-trichlorotriethylamine
  • 2,2’,2’’-trichloro-triethylamin
  • 2,2’,2’’-trichlorotriethylamine
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