OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS)
- CAS No.
- 88546-55-8
- Chemical Name:
- OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS)
- Synonyms
- OMEPRAZOLE SULPHONE;OMeprazole Related CoMpound A;5-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfonyl)-1H-benzo[d]iMidazole;H168/66;Amlodipine Impurity F;Esomeprazole USP RC A;Omeprazole Impurity Ⅰ;EsoMeprazol iMpurity D;EsoMeprazole iMpurity D;OMeprazole EP IMpurity D
- CBNumber:
- CB8505783
- Molecular Formula:
- C17H19N3O4S
- Molecular Weight:
- 361.42
- MDL Number:
- MFCD00869772
- MOL File:
- 88546-55-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Omeprazole impurity D European Pharmacopoeia (EP) Reference Standard | O0151000 | 15 mg | $254 |
| Omeprazole sulfone analytical standard | 94319 | 5mg | $435 |
| Omeprazole Related Compound A United States Pharmacopeia (USP) Reference Standard | 1478516 | 15mg | $1340 |
| Omeprazole Sulfone | O0707 | 100MG | $198 |
| Omeprazole sulfone ≥98% | 18882 | 5mg | $95 |
| More product size | |||
| Melting point | 80-82°C |
|---|---|
| Boiling point | 599.3±60.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | ≥40.6 mg/mL in DMSO,≥19.9 mg/mL in EtOH,insoluble in H2O |
| form | Solid |
| pka | 7.97±0.10(Predicted) |
| color | White to off-white |
| BRN | 8347309 |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C17H19N3O4S/c1-10-8-18-15(11(2)16(10)24-4)9-25(21,22)17-19-13-6-5-12(23-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20) |
| InChIKey | IXEQEYRTSRFZEO-UHFFFAOYSA-N |
| SMILES | O=S(C1=NC2=CC(OC)=CC=C2N1)(CC3=NC=C(C)C(OC)=C3C)=O |
| FDA UNII | 76X040Z74O |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 |
|||||||||
| NFPA 704 |
|
OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O0151000 | Omeprazole impurity D European Pharmacopoeia (EP) Reference Standard | 88546-55-8 | 15 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | 94319 | Omeprazole sulfone analytical standard | 88546-55-8 | 5mg | $435 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1478516 | Omeprazole Related Compound A United States Pharmacopeia (USP) Reference Standard | 88546-55-8 | 15mg | $1340 | 2026-04-30 | Buy |
| TCI Chemical | O0707 | Omeprazole Sulfone | 88546-55-8 | 100MG | $198 | 2026-04-30 | Buy |
| Cayman Chemical | 18882 | Omeprazole sulfone ≥98% | 88546-55-8 | 5mg | $95 | 2026-04-30 | Buy |
OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Chemical Properties,Uses,Production
Description
Omeprazole sulfone is the major metabolite of the gastric proton pump inhibitor, omeprazole . It is produced by cytochrome P450 (CYP)3A4 sulfoxidation of esomeprazole and is found in plasma. Omeprazole sulfone has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 18 μM).
Chemical Properties
Light Yellow Solid
Uses
A metabolite of Omeprazole.
Definition
ChEBI: Omeprazole sulfone is a sulfoxide and a member of benzimidazoles.
in vitro
omeprazole sulfone has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of cyp2c19 in pooled human liver microsomes with an ic50 of 18 μm [1].
in vivo
three hours after intake of 20 mg omeprazole only, the geometric mean plasma concentration of omeprazole sulfone were 106 nmol/l in 22 samples from subjects known to be extensive cyp2c19 metabolizers (em) and 672 nmol/l in the five subjects known to be poor cyp2c19 metabolizers (pm). the mean log10(omeprazole/omeprazole sulfone) ratio was 0.18 [4].
References
[1] nebert d w, russell d w. clinical importance of the cytochromes p450[j]. the lancet, 2002, 360(9340): 1155-1162.
[2] bel a, andersson t b, antonsson m, et al. stereoselective metabolism of omeprazole by human cytochrome p450 enzymes[j]. drug metabolism and disposition, 2000, 28(8): 966-972.
[3] nebert d w, russell d w. clinical importance of the cytochromes p450[j]. the lancet, 2002, 360(9340): 1155-1162.
[4] bttiger y. use of omeprazole sulfone in a single plasma sample as a probe for cyp3a4[j]. european journal of clinical pharmacology, 2006, 62(8): 621-625.
OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Tosun Pharmaceutical Ltd | +86-020-61855200-902 +8618124244216 | info@upharm.cn | China | 897 | 58 |
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +15184799099 | lbaochemicals@gmail.com | China | 671 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-01 | OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS)
88546-55-8
|
US $0.00 / kg | 1kg | 98% | Customise | Hefei Lbao Physical & Chemical Science Co.,Ltd | |
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2026-04-22 | Omeprazole metabolite Omeprazole sulfone
88546-55-8
|
US $42.00-156.00 / mg | 99.87% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2026-04-22 | Omeprazole metabolite Omeprazole sulfone
88546-55-8
|
US $42.00-156.00 / mg | 99.87% | 10g | TargetMol Chemicals Inc. |
-

- OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS)
88546-55-8
- US $0.00 / kg
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-

- Omeprazole metabolite Omeprazole sulfone
88546-55-8
- US $42.00-156.00 / mg
- 99.87%
- TargetMol Chemicals Inc.
-

- Omeprazole metabolite Omeprazole sulfone
88546-55-8
- US $42.00-156.00 / mg
- 99.87%
- TargetMol Chemicals Inc.
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