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Omeprazole

CAS No. 73590-58-6
Chemical Name: Omeprazole
Synonyms: miol;elgam;zimor;ANTRA;LOSEC;aulcer;prysma;ulcsep;MEPRAL;ZOLTUM
CBNumber: CB8160492
Molecular Formula: C17H19N3O3S
Formula Weight: 345.42
MOL File: 73590-58-6.mol
Omeprazole Property
Melting point : 156°C
Fp : 9℃
storage temp. : 2-8°C
solubility : H2O: 0.5 mg/mL
form : solid
color : white
Water Solubility : Soluble in water (0.5 mg/ml), DMSO (25 mg/ml), and ethanol (4.5 mg/ml).
Merck : 6845
Stability:: Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark.
CAS DataBase Reference: 73590-58-6(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes : Xi,T,F
Risk Statements : 36/37/38-39/23/24/25-23/24/25-11
Safety Statements : 26-36-37/39-45-36/37-16-7
RIDADR : UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany : 2
RTECS : DD9087000
Hazardous Substances Data: 73590-58-6(Hazardous Substances Data)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Omeprazole Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Solid
Uses
Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative
Uses
diuretic, sweetener, diagnostic aid
Uses
A selective proton pump and CYP inhibitor
Uses
Omeprazole Pellets are used in the treatment of Gastroesophageal reflux disease (GERD): A condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus)
Definition
ChEBI: A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Biological Activity
H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell).
Omeprazole Preparation Products And Raw materials
Raw materials
Potassium ethylxanthate Benzimidazole 3-Chloroperoxybenzoic acid Chloroform 3,5-Dimethyl-4-methoxy-2-pyridinemethanol 5-Methoxy-2-mercaptobenzimidazole o-Phenylenediamine
Preparation Products
Omeprazole Suppliers      Global( 308)Suppliers     
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3230 55
3600Chem 027-59207852 51787268 18827367472
027-59524646 sales@3600chem.com China 5000 55
WUHAN YUANCHENG GONGCHUANG TECHNOLOGY CO.,LTD 021 6858 0971/18964558747
gclb4r@ycphar.com China 1995 55
Guangzhou Kafen Biotech Co.,Ltd 020-31121484 18027468163 QQ:2355327168
020-31121510 gy@yccreate.com China 2000 55
Wuhan Hezhong Bio-chemical Manufacture co ltd 021-68580715 / 18930710487
nikki@pharm-china.com China 2019 55
ChemStrong Scientific Co.,Ltd 0755 66853366
0755 28363542 sales@chem-strong.com; China 10145 56
Wuhai Shuou Technology Co., Ltd. 18062666916 / QQ:2355326981
027-88217508 / 13667291122 mxy10@ycphar.com China 3203 55
Zhuhai Beri Medical Technology Co., Ltd +86(0756)8699 456
+86(0756)8699 456 sales@zhberi.com China 133 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96832 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40403 62
 
73590-58-6(Omeprazole)Related Search:
Pantoprazole Rabeprazole Lansoprazole 4-Hydroxy Omeprazole OMEPRAZOLE MAGNESIUM Omeprazole Dimethyl sulfoxide N,N-Dimethylformamide Methoxy Phenformin Dimethyl carbonate Benzimidazole Dimethyl phthalate Omeprazole sodium sterile ETHANE (Trifluoromethoxy)benzene 2,6-Lutidine OMEPRAZOLE PELLETS
1h-benzimidazole,5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulf 2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazol audazol aulcer belmazol ceprandal elgam emeproton gastrimut indurgan miol omapren ompanyt parizac pepticum prysma sanamidol secrepina ulceral ulcometion ulcsep zimor 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE 5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE 73590-58-6 Cell Signaling and Neuroscience Cell Biology BioChemical 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE H 168/68 GASTROLOC GASTROGARD ANTRA LOSEC MEPRAL Ion Channels Monovalent Ion Channels Potassium Channel Modulators Voltage-gated Ion Channels ZOLTUM (S)-OMEPRAZOLE R-(+)-OMEPRAZOLE PRILOSEC OMEPRAZOLE OMEPRAL MOPRAL OMEPRAZOL OMEPRAZOLE ANTRA, GASTROLOC, LOSEC \ H+/ K+ ATPASE INHIBITOR OMEPRAZOLE EP STANDARD Omerprazole C17H19N3O3S Antra[R] Losec[R] Mopral[R] Omepral[R] Antra, Gastrogard, Gastroloc, Losec, Mepral, Mopral, Omepral, Prilosec, Zoltum 1H-Benzimidazole, 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl-
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