4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
- CAS No.
- 933-76-6
- Chemical Name:
- 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
- Synonyms
- AKOS B029262;Emorfazone int;4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE;2-Methyl-4,5-dichloro-3-pyridazinone;4,5-dichloro-2-methylpyridazine-3-one;5-Dichloro-2-Methyl-3(2H)-pyridazinone;5-Dichloro-2-methylpyridazin-3(2H)-one;4,5-dichloro-2-methyl-3(2h)-pyridazinon;4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE, 9&;4,5-DICHLORO-2-METHYL-3(2H)-PYRIDAZINONE
- CBNumber:
- CB8728203
- Molecular Formula:
- C5H4Cl2N2O
- Molecular Weight:
- 179
- MDL Number:
- MFCD00051686
- MOL File:
- 933-76-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4,5-Dichloro-2-methyl-3(2H)-pyridazinone 97% | 597716 | 5g | $149 |
| 4,5-Dichloro-2-methyl-3(2H)-pyridazinone >98.0%(GC) | D5324 | 1g | $20 |
| 4,5-Dichloro-2-methyl-3(2H)-pyridazinone >98.0%(GC) | D5324 | 5g | $80 |
| 2-Methyl-4,5-dichloro-3-pyridazinone | M299780 | 10g | $115 |
| 4,5-Dichloro-2-methylpyridazin-3(2H)-one | 4H17-5-Y1 | 5G | $88 |
| More product size | |||
| Melting point | 87-91 °C(lit.) |
|---|---|
| Boiling point | 197.2±50.0 °C(Predicted) |
| Density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | soluble in Ethanol |
| form | powder to crystal |
| pka | -3.57±0.20(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C5H4Cl2N2O/c1-9-5(10)4(7)3(6)2-8-9/h2H,1H3 |
| InChIKey | ACKBTCUMGAHRIE-UHFFFAOYSA-N |
| SMILES | C1(=O)N(C)N=CC(Cl)=C1Cl |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H317-H319-H335 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-43 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UR6188000 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29339980 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 597716 | 4,5-Dichloro-2-methyl-3(2H)-pyridazinone 97% | 933-76-6 | 5g | $149 | 2023-06-20 | Buy |
| TCI Chemical | D5324 | 4,5-Dichloro-2-methyl-3(2H)-pyridazinone >98.0%(GC) | 933-76-6 | 1g | $20 | 2026-04-30 | Buy |
| TCI Chemical | D5324 | 4,5-Dichloro-2-methyl-3(2H)-pyridazinone >98.0%(GC) | 933-76-6 | 5g | $80 | 2026-04-30 | Buy |
| TRC | M299780 | 2-Methyl-4,5-dichloro-3-pyridazinone | 933-76-6 | 10g | $115 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H17-5-Y1 | 4,5-Dichloro-2-methylpyridazin-3(2H)-one | 933-76-6 | 5G | $88 | 2021-12-16 | Buy |
4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE Chemical Properties,Uses,Production
Chemical Properties
Off-white to yellow low crystalline powder
Uses
4,5-Dichloro-2-methyl-3(2H)-pyridazinone can be used in the synthesis of 4-amino-3(2H)-pyridazinones and 5-amino-3(2H)-pyridazinones via reaction with N-benzylaminoethanol.
Definition
ChEBI: 4,5-Dichloro-2-methyl-3(2H)-pyridazinone is a pyridazinone.
Synthesis
932-22-9
74-88-4
933-76-6
Step 1: A round bottom flask was charged with 4,5-dichloropyridazin-3(2H)-one (10.0 g, 60.6 mmol), potassium carbonate (16.8 g, 121.2 mmol), iodomethane (4.0 mL, 64.3 mmol) and acetonitrile (80 mL). The reaction mixture was heated to reflux for 12 hours and then cooled to room temperature. After completion of the reaction, the mixture was filtered and the filtrate was concentrated. The residue was purified by column chromatography (dichloromethane as eluent) to afford 4,5-dichloro-2-methylpyridazin-3-one 8.21 g (76% yield). The product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.18 (s, 1H), 3.70 (s, 3H); mass spectrum (m/z) = 179 ([M+H]+).
References
[1] Patent: WO2009/142732, 2009, A2. Location in patent: Page/Page column 61-62
[2] Patent: WO2011/15629, 2011, A1. Location in patent: Page/Page column 46; 47
[3] Journal of Heterocyclic Chemistry, 1996, vol. 33, # 6, p. 1579 - 1582
[4] Patent: WO2013/50421, 2013, A1. Location in patent: Page/Page column 37
[5] Journal of the Korean Chemical Society, 2014, vol. 58, # 1, p. 140 - 144
4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
View Lastest Price from 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2022-01-04 | 4,5-Dichloro-2-Methylpyridazin-3-one
933-76-6
|
US $0.00-0.00 / KG | 1g | 98%minHPLC | 100kgs/month | Shanghai Rlavie Technology Co ltd | |
![]() |
2020-04-30 | 4,5-Dichloro-2-Methylpyridazin-3-one
933-76-6
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
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2019-07-06 | 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
933-76-6
|
US $1.00 / KG | 1KG | 98% | 150KG | Career Henan Chemical Co |
-

- 4,5-Dichloro-2-Methylpyridazin-3-one
933-76-6
- US $0.00-0.00 / KG
- 98%minHPLC
- Shanghai Rlavie Technology Co ltd
-

- 4,5-Dichloro-2-Methylpyridazin-3-one
933-76-6
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
933-76-6
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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