ChemicalBook >> CAS DataBase List >>Scutellarin

Scutellarin

CAS No.
27740-01-8
Chemical Name:
Scutellarin
Synonyms
SCUTELLARIN;Scutellarin B;Scutellarin,NA;Scutellarin-RM;Scutellarin ,98%;Erigeron extract;Scutellarin Powder;Scutellarin USP/EP/BP;Scutellarin 27740-01-8;Scutellarin (6CI, 7CI)
CBNumber:
CB9117918
Molecular Formula:
C21H18O12
Molecular Weight:
462.36
MDL Number:
MFCD01861503
MOL File:
27740-01-8.mol
Last updated:2024-10-31 21:04:56

Scutellarin Properties

Melting point 300~301℃
Boiling point 891.6±65.0 °C(Predicted)
Density 1.810±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Very Slightly, Sonicated)
pka 2.72±0.70(Predicted)
form Solid
color Light Yellow to Yellow
BRN 71779
CAS DataBase Reference 27740-01-8(CAS DataBase Reference)
FDA UNII 16IGP0ML9A

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  3
HS Code  29389090

Scutellarin price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 73577 Scutellarin analytical standard 27740-01-8 10mg $290.4 2024-03-01 Buy
Cayman Chemical 27461 Scutellarin 27740-01-8 10mg $44 2024-03-01 Buy
Cayman Chemical 27461 Scutellarin 27740-01-8 100mg $426 2024-03-01 Buy
Cayman Chemical 27461 Scutellarin 27740-01-8 25mg $172 2024-03-01 Buy
Cayman Chemical 27461 Scutellarin 27740-01-8 50mg $257 2024-03-01 Buy
Product number Packaging Price Buy
73577 10mg $290.4 Buy
27461 10mg $44 Buy
27461 100mg $426 Buy
27461 25mg $172 Buy
27461 50mg $257 Buy

Scutellarin Chemical Properties,Uses,Production

Description

Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.

Uses

Scutellarin is an active flavonoid component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz. Scutellarin is used as a micrpcirculation promoter for the treatment of cardio-cerebrovascular diseases. Studies suggest that Scutellarin has anti-cancer properties and has been shown to enhance apoptosis of tumor cells.

Definition

ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.

119262-68-9
27740-01-8
Synthesis of Scutellarin from scutellarin Methylester
Global( 285)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3002 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
+8615373025980 clara@hbshengyang.com China 874 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29886 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202 sale02@cqherb.com CHINA 376 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58

View Lastest Price from Scutellarin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Scutellarin pictures 2024-10-31 Scutellarin
27740-01-8
US $45.00-134.00 / mg 99.32% 10g TargetMol Chemicals Inc.
Scutellarin pictures 2024-10-31 Scutellarin
27740-01-8
US $200.00-85.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
Scutellarin; Breviscapinun pictures 2024-10-31 Scutellarin; Breviscapinun
27740-01-8
US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
  • Scutellarin pictures
  • Scutellarin
    27740-01-8
  • US $45.00-134.00 / mg
  • 99.32%
  • TargetMol Chemicals Inc.
  • Scutellarin pictures
  • Scutellarin
    27740-01-8
  • US $200.00-85.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd

Scutellarin Spectrum

SCUTELLARIN, 98+% BY HPLC (4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronicacid,5,6-dihydroxy-2- 4',5,6-Trihydroxy-7-[(β-D-glucopyranuronosyl)oxy]flavone 4',5,6-Trihydroxyflavon-7-yl β-D-glucopyranosiduronic acid 5,6-Dihydroxy-4-oxo-2-(4-hydroxyphenyl)-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid Scutellarein 4'-methyl ether 7-glucuronide Scutellarein 7-glucuronide SCUTELLARIN SCUTELLAREIN 7-O-GLUCURONIDE Scutellarin ,98% Scutellarin B 7-(beta-d-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one 4',5,6,7-Tetrahydroxyflavone 7-β-D-Glucopyranuronoside 5,6-Dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid Scutellarein 7-O-β-D-Glucuronide Scutellarein 7-β-D-Glucuronoside Scutellarein 7-b-D-glucuronide Scutellarin 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Scutellarin 27740-01-8 Erigeron extract β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl Scutellarin USP/EP/BP (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid Reference Substance Scutellarin (6CI, 7CI) Scutellarin Powder Scutellarin,NA Scutellarin-RM 27740-01-8 Miscellaneous Natural Products chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors