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Scutellarin

Scutellarin structure

CAS No.: 27740-01-8

Chemical Name:: Scutellarin

Synonyms: SCUTELLARIN;Scutellarin B;Scutellarin,NA;Scutellarin-RM;Scutellarin ,98%;Erigeron extract;Scutellarin Powder;Scutellarin USP/EP/BP;Scutellarin 27740-01-8;Scutellarin (6CI, 7CI)

CBNumber:: CB9117918

Molecular Formula:: C21H18O12

Molecular Weight:: 462.36

MDL Number:: MFCD01861503

MOL File:: 27740-01-8.mol

Last updated:2024-10-31 21:04:56

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Scutellarin Properties

Melting point	300～301℃
Boiling point	891.6±65.0 °C(Predicted)
Density	1.810±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO (Slightly), Methanol (Very Slightly, Sonicated)
pka	2.72±0.70(Predicted)
form	Solid
color	Light Yellow to Yellow
BRN	71779
CAS DataBase Reference	27740-01-8(CAS DataBase Reference)
FDA UNII	16IGP0ML9A

SAFETY

Risk and Safety Statements

Safety Statements	24/25
WGK Germany	3
HS Code	29389090

Scutellarin price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	73577	Scutellarin analytical standard	27740-01-8	10mg	$290.4	2024-03-01	Buy
Cayman Chemical	27461	Scutellarin	27740-01-8	10mg	$44	2024-03-01	Buy
Cayman Chemical	27461	Scutellarin	27740-01-8	100mg	$426	2024-03-01	Buy
Cayman Chemical	27461	Scutellarin	27740-01-8	25mg	$172	2024-03-01	Buy
Cayman Chemical	27461	Scutellarin	27740-01-8	50mg	$257	2024-03-01	Buy

Product number	Packaging	Price	Buy
73577	10mg	$290.4	Buy
27461	10mg	$44	Buy
27461	100mg	$426	Buy
27461	25mg	$172	Buy
27461	50mg	$257	Buy

Scutellarin Chemical Properties,Uses,Production

Description

Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.

Uses

Scutellarin is an active flavonoid component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz. Scutellarin is used as a micrpcirculation promoter for the treatment of cardio-cerebrovascular diseases. Studies suggest that Scutellarin has anti-cancer properties and has been shown to enhance apoptosis of tumor cells.

Definition

ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.

Scutellarin synthesis

Synthesis of Scutellarin from scutellarin Methylester

Scutellarin Preparation Products And Raw materials

Raw materials

4',5,6,7-Tetrahydroxyflavone tetraacetate (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic SCUTELLAREIN scutellarin Methylester

Preparation Products

cirsimaritin SCUTELLAREIN-7-METHYL ETHER

Scutellarin Suppliers

Global( 285)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3002	58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	+8615373025980	clara@hbshengyang.com	China	874	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29886	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	+8613815430202	sale02@cqherb.com	CHINA	376	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58

Supplier	Advantage
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	58
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Scutellarin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-10-31	Scutellarin 27740-01-8	US $45.00-134.00 / mg		99.32%	10g	TargetMol Chemicals Inc.
2024-10-31	Scutellarin 27740-01-8	US $200.00-85.00 / kg	1kg	99%	20ton	Hebei Zhuanglai Chemical Trading Co.,Ltd
2024-10-31	Scutellarin; Breviscapinun 27740-01-8	US $0.00 / KG	1KG	≥98% HPLC	1000KG	Changsha Staherb Natural Ingredients Co., Ltd.

Scutellarin
27740-01-8
US $45.00-134.00 / mg
99.32%
TargetMol Chemicals Inc.

Scutellarin
27740-01-8
US $200.00-85.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co.,Ltd

Scutellarin; Breviscapinun
27740-01-8
US $0.00 / KG
≥98% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

Scutellarin Spectrum

Scutellarin(27740-01-8)¹HNMR

27740-01-8(Scutellarin)Related Search:

Baicalin Baicalein SCUTELLAREIN Isoimperatorin Genistin

Isoliquiritigenin 5,7-Dihydrox -4'-methoxyisoflavone FLAVONE APIGENIN-7-GLUCURONIDE Wogonoside

Tetramethyl-O-scutellarin BAICALIN HYDRATE 3',5'-Dimethoxytricetin 7-O-β-D-glucopypranoside 7-HYDROXYFLAVONE-BETA-D-GLUCOSIDE BREVISCAPIN

Scutellarin ERIGERON BREVISCAPUS SCUTELLARIN:>5%,DCQ:>5%

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SCUTELLARIN, 98+% BY HPLC (4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronicacid,5,6-dihydroxy-2- 4',5,6-Trihydroxy-7-[(β-D-glucopyranuronosyl)oxy]flavone 4',5,6-Trihydroxyflavon-7-yl β-D-glucopyranosiduronic acid 5,6-Dihydroxy-4-oxo-2-(4-hydroxyphenyl)-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid Scutellarein 4'-methyl ether 7-glucuronide Scutellarein 7-glucuronide SCUTELLARIN SCUTELLAREIN 7-O-GLUCURONIDE Scutellarin ,98% Scutellarin B 7-(beta-d-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one 4',5,6,7-Tetrahydroxyflavone 7-β-D-Glucopyranuronoside 5,6-Dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid Scutellarein 7-O-β-D-Glucuronide Scutellarein 7-β-D-Glucuronoside Scutellarein 7-b-D-glucuronide Scutellarin 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Scutellarin 27740-01-8 Erigeron extract β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl Scutellarin USP/EP/BP (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid Reference Substance Scutellarin (6CI, 7CI) Scutellarin Powder Scutellarin,NA Scutellarin-RM 27740-01-8 Miscellaneous Natural Products chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors