PVM/MA
- CAS No.
- 1644545-52-7
- Chemical Name:
- PVM/MA
- Synonyms
- AG881;E7386;AG081;HS-01;PVM/MA;AG-881;E-7386;s-22611;FF10101;CS-2621
- CBNumber:
- CB91403717
- Molecular Formula:
- C14H13ClF6N6
- Molecular Weight:
- 414.74
- MDL Number:
- MFCD31630835
- MOL File:
- 1644545-52-7.mol
Boiling point | 467.5±55.0 °C(Predicted) |
---|---|
Density | 1.491±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml |
form | A crystalline solid |
pka | 1.49±0.41(Predicted) |
FDA UNII | 789Q85GA8P |
NCI Drug Dictionary | vorasidenib |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
NFPA 704 |
|
PVM/MA price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 1mg | $110 | 2024-03-01 | Buy |
Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 10mg | $757 | 2024-03-01 | Buy |
Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 5mg | $433 | 2024-03-01 | Buy |
ChemScene | CS-8033 | Vorasidenib 99.87% | 1644545-52-7 | 5mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-8033 | Vorasidenib 99.87% | 1644545-52-7 | 10mg | $250 | 2021-12-16 | Buy |
PVM/MA Chemical Properties,Uses,Production
Uses
PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.
Synthesis
Maleic anhydride (MA) was added to a solvent mixture of cyclohexane and ethyl acetate in a polymerizer equipped with an agitator, a reflux condenser, and an inner temperature-controlling device. The polymerizer was purged of air and filled with nitrogen. The solution was heated to 70 °C, and then an initiator solution (lauroyl peroxide dissolved in ethyl acetate) and Methyl vinyl ether (MVE) were added to the polymerizer in a dropwise manner. A slurry was obtained, which was filtered and dried under a vacuum to obtain a white powdery copolymer.
PVM/MA Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Related articles
- The brief introduction of PVM/MA
- The copolymer of MVE and maleic anhydride (MA) is most widely used.
- Mar 14,2024
View Lastest Price from PVM/MA manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2021-10-08 | Vorasidenib;AG-881
1644545-52-7
|
US $0.00-0.00 / g | 1g | 98% | 100kgs | Wuhan Nutra Biotechnology Co.,Ltd |
-
- Vorasidenib;AG-881
1644545-52-7
- US $0.00-0.00 / g
- 98%
- Wuhan Nutra Biotechnology Co.,Ltd