Genistin
- CAS No.
- 529-59-9
- Chemical Name:
- Genistin
- Synonyms
- GENISTEIN-7-O-GLUCOSIDE;GENISTEIN-7-GLUCOSIDE;genistein 7-O-β-D-glucoside;GENISTIN;NSC 5112;genistine;Genistoside;Genistin ,98%;GENISTIN >99%;Genistin (30 mg)
- CBNumber:
- CB9769395
- Molecular Formula:
- C21H20O10
- Molecular Weight:
- 432.38
- MDL Number:
- MFCD00016883
- MOL File:
- 529-59-9.mol
- MSDS File:
- SDS
Melting point | 254°C |
---|---|
Boiling point | 256 °C |
alpha | D21 -28° (c = 0.6 in 0.02N NaOH); D26 -21.4° (pyridine) |
Density | 1.642±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: 10 mg/mL |
pka | 6.12±0.20(Predicted) |
color | Off-white |
Merck | 13,4402 |
BRN | 64479 |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week. |
InChIKey | ZCOLJUOHXJRHDI-CMWLGVBASA-N |
LogP | 0.790 (est) |
FDA UNII | 1POG3SCN5T |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319 |
Precautionary statements | P261-P305+P351+P338 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
RTECS | DJ3093000 |
F | 10 |
HS Code | 29389090 |
Genistin price More Price(61)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 1288805 | Genistin United States Pharmacopeia (USP) Reference Standard | 529-59-9 | 30mg | $1320 | 2024-03-01 | Buy |
Sigma-Aldrich | 05380590 | Genistin primary reference standard | 529-59-9 | 25mg | $555 | 2023-06-20 | Buy |
Alfa Aesar | J63445 | Genistin, 99+% | 529-59-9 | 100mg | $487 | 2024-03-01 | Buy |
Cayman Chemical | 14174 | Genistin ≥98% | 529-59-9 | 5mg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 14174 | Genistin ≥98% | 529-59-9 | 10mg | $112 | 2024-03-01 | Buy |
Genistin Chemical Properties,Uses,Production
Description
Genistin is a natural isoflavone isolated from legumes, including soy and kudzu. It is a phytoestrogen, as it stimulates the growth of estrogen-
Chemical Properties
White Powder
Uses
Genistin has been used for immune reactivity against influenza viruses in vitro and as an internal standard in isoflavones quantification.
Uses
A derivative of Genistein. Inhibitor
Uses
Glucoside of genistein that inhibits protein tyrosine kinase
Uses
An isoflavone glycoside which is an inactive analog of the PTK inhibitor Genistein.
Definition
ChEBI: Genistein 7-O-beta-D-glucoside is a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a genistein. It is a conjugate acid of a genistein 7-O-beta-D-glucoside(1-).
General Description
Genistin belongs to the class of isoflavone glycosides generally extracted from soybeans.
Biochem/physiol Actions
Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.
Purification Methods
Genistin is repeatedly crystallised from hot 80% EtOH/water and treated with charcoal (Nuchar) until free from saponin. The presence of saponin is detected by adding crystals to conc H2SO4 when the citron yellow colour changes to red, then purple. Pure genistin does not change colour. UV in 85% EtOH has max at 262.5nm. [Walter J Am Chem Soc 63 3273 1941, Beilstein 18 III/IV 2732.]
References
1) Uchiyama et al. (2005), Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin; Biochim. Biophys. Acta, 1725 298 2) Choi et al. (2007), Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells; Life Sci, 80 1403 3) Russo et al. (2006), Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells; J. Nutr. Biochem., 17 103
Genistin Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from Genistin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-06-03 | Genistin
529-59-9
|
US $0.00 / MG | 20MG | 99% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | ||
2023-02-24 | Genistin
529-59-9
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | ||
2021-07-13 | Genistin
529-59-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |