ChemicalBook >> CAS DataBase List >>2-Fluoroadenine
2-Fluoroadenine
- CAS No.
- 700-49-2
- Chemical Name:
- 2-Fluoroadenine
- Synonyms
- 2-Fluoro-9H-purin-6-amine;2-fluoro-7H-purin-6-aMine;2-fad;nsc27364;uoroadenine;TCMDC-124283;2-fluoro-adenin;2-FLUOROADENINE;BUTTPARK 25\01-01;2-Fluoroadenine>
- CBNumber:
- CB9854134
- Molecular Formula:
- C5H4FN5
- Molecular Weight:
- 153.12
- MDL Number:
- MFCD01632749
- MOL File:
- 700-49-2.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:03:02
| Melting point | >350 °C(lit.) |
|---|---|
| Boiling point | 239.6±50.0 °C(Predicted) |
| Density | 2.05±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Sparingly, Sonicated, Heated), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 6.84±0.20(Predicted) |
| color | White to Light Yellow |
| CAS DataBase Reference | 700-49-2(CAS DataBase Reference) |
| FDA UNII | 2C8H3H4EBG |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AU6264700 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, IRRITANT-HARMFUL | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
2-Fluoroadenine price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 535087 | 2-Fluoroadenine 96% | 700-49-2 | 1g | $146 | 2024-03-01 | Buy |
| TCI Chemical | F0647 | 2-Fluoroadenine >98.0%(HPLC)(T) | 700-49-2 | 200mg | $18 | 2024-03-01 | Buy |
| TCI Chemical | F0647 | 2-Fluoroadenine >98.0%(HPLC)(T) | 700-49-2 | 1g | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 30421 | 2-Fluoroadenine | 700-49-2 | 500mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 30421 | 2-Fluoroadenine | 700-49-2 | 1g | $115 | 2024-03-01 | Buy |
2-Fluoroadenine Chemical Properties,Uses,Production
Description
2-Fluoroadenine is a purine nucleoside analog which has been investigated for suicide gene therapy for human malignancy. It has been used in the synthesis of heat shock protein 90 (Hsp90) inhibitors that have anticancer activity in vitro. It is also cytotoxic to CEM human leukemia cells with an IC50 value of 0.15 μM.
Chemical Properties
white to light yellow crystal powder
Uses
2-Fluoroadenine is a fluorinated heterocyclic 2-ring compound. It is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. 2-Fluoroadenine has been used as an intermediate for antineoplastic drugs such as fludarabine. fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia.
Uses
A purine nucleoside phosphorylase gene therapy for human malignancy.
Definition
ChEBI: 2-fluoroadenine is an organofluorine compound that is adenine in which the hydrogen at position 2 (the carbon between the two nitrogens of the pyrimidine ring) is replaced by a fluorine. It has a role as an antineoplastic agent. It is an organofluorine compound and a member of purines.
2-Fluoroadenine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 360)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 16801 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
View Lastest Price from 2-Fluoroadenine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-11 | TCMDC-124283
700-49-2
|
US $122.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2022-09-23 | 2-Fluoroadenine
700-49-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2022-02-25 | 2-Fluoroadenine
700-49-2
|
US $10.00 / KG | 1KG | 99% | 500tons/month | Shanxi Naipu Import and Export Co.,Ltd |
-
- TCMDC-124283
700-49-2
- US $122.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoroadenine
700-49-2
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Fluoroadenine
700-49-2
- US $10.00 / KG
- 99%
- Shanxi Naipu Import and Export Co.,Ltd
700-49-2(2-Fluoroadenine)Related Search:
2-fluoro-1h-purin-6-amin
2-fluoro-1h-purin-6-amine
2-fluoro-adenin
6-amino-2-fluoro-purin
nsc27364
6-Amino-2-fluoro-1H-purine
BUTTPARK 25\01-01
2-FLUORO-6-AMINOPURINE
2-FLUOROADENINE
2-FLUORO-7(9)H-PURIN-6-YLAMINE
6-AMINO-2-FLUOROPURINE
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2-fad
Fludarabine Phosphate EP Impurity D
Fludarabine Phosphate Impurity 4
uoroadenine
Fludarabine Phosphate impurity 4/Fludarabine Phosphate EP Impurity D/2-fluoroadenine
Fludarabine EP impurity D (2-Fluoroadenine )
Fludarabine EP impurity D
Fludarabine Phosphate Impurity 4（Fludarabine Phosphate EP Impurity D）
2-Fluoroadenine>
9H-Purin-6-amine, 2-fluoro-
2-Fluoroadenine USP/EP/BP
2-Fluoroadenine(700-49-2)
Fludarabine Impurity 5
2-Fluoro-9H-purin-6-amine
2-fluoro-7H-purin-6-aMine
TCMDC-124283
700-49-2
C5H4FN5
C5H4N5F
Purines
Heterocyclic Building Blocks
Building Blocks
Biochemistry
Nucleobases and their analogs
Nucleosides, Nucleotides & Related Reagents
Purine
Chemical Amines
Purines
Bases & Related Reagents
Heterocycles
Nucleotides
Fused Ring Systems
Miscellaneous
Amines
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