ChemicalBook
Chinese english Germany Korea

エタノール

エタノール 化学構造式
64-17-5
CAS番号.
64-17-5
化学名:
エタノール
别名:
消毒用エタライト;オー消エタ;テクソール;消エタサラコール;アルコール;消毒用エタノールα;消毒用エタノール;酒精;メチルカルビノール;純生局エタ;水和エチル;エチルアルコール;消毒用エタIP;消エタコア;純生消エタ;消毒用エタライト-B;エタン-1-オール;消毒用エタノールIPA;エコ消エタ;エタノール
英語化学名:
Etanol
英語别名:
RGA;etha;Spirt;Tecsol;Thanol;Etanol;C2H5OH;Jaysol;Synasol;tecsolc
CBNumber:
CB2362508
化学式:
C2H6O
分子量:
46.06844
MOL File:
64-17-5.mol

エタノール 物理性質

融点 :
-114°C
沸点 :
78°C
比重(密度) :
0.789 g/mL at 20 °C
蒸気密度:
1.59 (vs air)
蒸気圧:
43 mmHg at 20 °C
FEMA :
2419 | ETHYL ALCOHOL
屈折率 :
1.3614
闪点 :
12°C
貯蔵温度 :
Store at RT.
溶解性:
water: soluble (completely)
酸解離定数(Pka):
16(at 25℃)
外見 :
Liquid. Colorless liquid / invisible vapor.
色:
APHA: ≤10
比重:
0.80872~0.81601
臭い (Odor):
Pleasant alcoholic odor detectable at 49 to 716 ppm (mean = 180 ppm)
Relative polarity:
0.654
PH:
7.0 (10g/l, H2O, 20℃)
爆発限界(explosive limit):
3.1-27.7%(V)(ethanol)
水溶解度 :
miscible
Sensitive :
Hygroscopic
極大吸収波長 (λmax):
λ: 240 nm Amax: 0.40
λ: 250 nm Amax: 0.30
λ: 260 nm Amax: 0.30
λ: 270 nm Amax: 0.10
λ: 340 nm Amax: 0.10
JECFA Number:
41
Merck :
14,3760
BRN :
1718733
暴露限界値:
TLV-TWA 1900 mg/m3 (1000 ppm) (ACGIH).
安定性::
Stable. Substances to be avoided include strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali metals, ammonia, moisture. Forms explosive mixtures with air. Hygroscopic.
CAS データベース:
64-17-5(CAS DataBase Reference)
NISTの化学物質情報:
Ethanol(64-17-5)
EPAの化学物質情報:
Ethanol(64-17-5)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  F,T,Xn,N
Rフレーズ  11-10-36/37/38-39/23/24/25-23/24/25-68/20/21/22-20/21/22-52/53-51/53
Sフレーズ  16-7-36-26-45-36/37-61-24/25-2017/7/16
RIDADR  1170
WGK Germany  nwg
RTECS 番号 KQ6300000
自然発火温度 363 °C
TSCA  Yes
国連危険物分類  3
容器等級  II
HSコード  22071000
有毒物質データの 64-17-5(Hazardous Substances Data)
毒性 LD50 in young, old rats (g/kg): 10.6, 7.06 orally (Wiberg)
消防法 危険物第4類アルコール類
化審法 一般化学物質
安衛法 57,57-2
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H225 引火性の高い液体および蒸気 引火性液体 2 危険 P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H226 引火性の液体および蒸気 引火性液体 3 警告
H302 飲み込むと有害 急性毒性、経口 4 警告 P264, P270, P301+P312, P330, P501
H313 皮膚に接触すると有害のおそれ 急性毒性、経皮 5 P312
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 P264, P280, P305+P351+P338,P337+P313P
H333 吸入すると有害のおそれ 急性毒性、吸入 5 P304+P312
H370 臓器の障害 特定標的臓器有害性、単回暴露 1 危険 P260, P264, P270, P307+P311, P321,P405, P501
H371 臓器の障害のおそれ 特定標的臓器有害性、単回暴露 2 警告 P260, P264, P270, P309+P311, P405,P501
H402 水生生物に有害 水生環境有害性、急性毒性 3
H412 長期的影響により水生生物に有害 水生環境有害性、慢性毒性 3 P273, P501
注意書き
P210 熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P303+P361+P353 皮膚(または髪)に付着した場合:直ちに汚染された衣 類をすべて脱ぐこと/取り除くこと。皮膚を流水/シャワー で洗うこと。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P337+P313 眼の刺激が続く場合:医師の診断/手当てを受けること。
P370+P378 火災の場合:消火に...を使用すること。
P403+P235 換気の良い場所で保管すること。涼しいところに 置くこと。
P405 施錠して保管すること。

エタノール 価格 もっと(163)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01W0105-0048 エタノール (95) 94.8~95.8 vol% (by density)
Ethanol (95) 94.8~95.8 vol% (by density)
64-17-5 500mL ¥2110 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01W0105-0047 エタノール(95) 94.8?95.8 vol% (by density)
Ethanol(95) 94.8?95.8 vol% (by density)
64-17-5 500mL ¥2210 2018-12-26 購入
関東化学株式会社(KANTO) 14032-08 エタノール(99.5) >99.5%(GC)
Ethanol (99.5) >99.5%(GC)
64-17-5 500mL ¥4600 2018-12-13 購入
関東化学株式会社(KANTO) 14032-1B エタノール(99.5) >99.5%(GC)
Ethanol (99.5) >99.5%(GC)
64-17-5 1L ¥5600 2018-12-13 購入
Sigma-Aldrich Japan 02857 エタノール
purum, fine spirit, denaturated with 4.8% methanol, F25 METHYL1, ~96% (based on denaturant-free substance)
64-17-5 1l ¥5900 2018-12-25 購入

エタノール 化学特性,用途語,生産方法

外観

無色透明な液体

定義

本品は、エタノール(*)に、変性剤を加えたものである。参照表示名称:エタノール

溶解性

水及びジエチルエーテルに極めて溶けやすい。

用途

その他の代表用途は、工業用原料(洗剤、塗料、溶剤など)である。

用途

汎用試薬(95%指定のもの)、溶剤等。

用途

高純度溶媒を使用する小実験に、或いは使用中の汚染を避けるため小包装を必要とする場合に使用される。

用途

汎用試薬(95%指定のもの)、溶剤、有機合成原料、試液調製原料、消毒殺菌剤。

用途

多くのエチルアルコールは希釈してアルコール飲料、実験室用溶剤、変性アルコール、医薬品(消毒剤、ローション、トニック、コロン類)製造、香粧品工業、有機合成化学工業の溶剤、ガソリンのオクタン価向上剤、医薬品助剤(溶剤)

化粧品の成分用途

減粘剤、抗菌剤、溶剤、収れん剤、香料、消泡剤

効能

抗悪性腫瘍薬, 外皮用殺菌消毒薬, 溶解剤

主な用途/役割

溶剤型接着剤、水性型エマルション系接着剤、エアゾール接着剤に使用される。

商品名

エタノール (小堺製薬); 無水エタノール (コニシ); 無水エタノール (サンケミファ); 無水エタノール (シオエ製薬); 無水エタノール (マイラン製薬); 無水エタノール (ヤクハン製薬); 無水エタノール (丸石製薬); 無水エタノール (丸石製薬); 無水エタノール (丸石製薬); 無水エタノール (今津薬品工業); 無水エタノール (健栄製薬); 無水エタノール (司生堂製薬); 無水エタノール (吉田製薬); 無水エタノール (大成薬品工業); 無水エタノール (小堺製薬); 無水エタノール (小堺製薬); 無水エタノール (山善製薬); 無水エタノール (扶桑薬品工業); 無水エタノール (日興製薬); 無水エタノール (日興製薬); 無水エタノール (日興製薬); 無水エタノール (東洋製薬化成); 無水エタノール (東海製薬); 無水エタノール (東豊薬品)

使用上の注意

1.損傷皮膚及び粘膜には使用しないこと。(刺激作用を有するので)。2.副作用(1)過敏症 発疹等の過敏症状があらわれることがあるので、このような場合には使用を中止すること。(2)皮膚 刺激症状があらわれることがあるので、このような症状があらわれた場合には使用を中止すること。3.適用上の注意(1)人体 ア)原液又は濃厚液は刺激作用があるので経口投与しないこと。 イ)眼に入らないように注意すること。入った場合には水でよく洗い流すこと。 ウ)広範囲又は長期間使用する場合には、蒸気の吸入に注意すること。 エ)同一部位に反復使用した場合には、脱脂等による皮膚荒れを起こすことがあるので注意すること。(2)その他本剤は血清、膿汁等の蛋白質を凝固させ、内部にまで浸透しないことがあるので、これらが付着している医療器具等に用いる場合には、十分に洗い落としてから使用すること。(取扱上の注意)(1)金属器具を長時間浸漬する必要がある場合には、腐食を防止するために0.2~1.0%の亜硝酸ナトリウムを添加すること。(2)合成ゴム製品、合成樹脂製品、光学器具、鏡器具、塗装カテーテル等には、変質するものがあるので、このような器具は長時間浸漬しないこと。(3)貯法:遮光した気密容器に入れ、火気を避けて保存する。

説明

Ethyl alcohol, also called ethanol, absolute alcohol, or grain alcohol, is a clear, colorless, flammable liquid with a pleasant odor. It is associated primarily with alcoholic beverages, but it has numerous uses in the chemical industry. The word alcohol is derived from the Arabic word al kuhul, which was a fine powder of the element antimony used as a cosmetic. In Medieval times, the word al kuhul came to be associated with the distilled products known as alcohols. The hydroxyl group, -OH, bonded to a carbon, characterizes alcohols. Ethyl is derived from the root of the two-carbon hydrocarbon ethane.

化学的特性

In the BP 2009, the term ‘alcohol’; used without other qualification refers to ethanol containing ≥99.5% v/v of C2H6O. The term‘alcohol’, without other qualification, refers to ethanol 95.1–96.9% v/v. Where other strengths are intended, the term ‘alcohol’ or ‘ethanol’is used, followed by the statement of the strength. In the PhEur 6.0, anhydrous ethanol contains not less than 99.5% v/v of C2H6O at 208℃. The term ethanol (96%) is used to describe the material containing water and 95.1–96.9% v/v of C2H6O at 208℃.

化学的特性

Colourless, clear, volatile, flammable liquid, hygroscopic

化学的特性

Ethyl alcohol is a colorless flammable liquid with a typical lower alcohol odor and is miscible in water in all proportions. It is stable and hygroscopic. It is incompatible with strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali metals, ammonia, and moisture. Ethyl alcohol forms explosive mixtures with air. Ethyl alcohol is the most common solvent used in aerosols, cosmetics, pharmaceuticals, alcoholic beverages, vinegar production, and in the chemical synthesis of a large variety of products in different industries. For instance, in the manufacture of plastics, lacquers, polishes, plasticizers, perfumes, adhesives, rubber accelerators, explosives, synthetic resins, nitrocellulose, inks, preservatives, and as a fuel.

化学的特性

Ethyl alcohol is a colorless, volatile, flammable liquid with a sweet, fruity odor. The Odor Threshold is 0.1355 ppm.

来歴

Alcohol is produced naturally from the fermentation of sugars, and it is assumed that prehistoric humans consumed alcohol when eating fermented fruits. The earliest direct evidence of alcohol consumption dates from the Neolithic period 10,000 years ago and consists of stone jugs used for holding alcoholic beverages. Ancient records and art from Egypt, Babylon, Mesopotamia, and other early civilizations indicate the use of alcohol as a beverage, medicine, and ceremonial drink. Records also show that the intoxicating effects of alcohol were known for thousands of years b.c.e. Alcoholic drinks were stored in Egyptian burial tombs, and deities devoted to alcoholic beverages were worshiped by different civilizations. As the human population expanded, alcoholic drinks assumed a prominent role in different cultures; for example, numerous references are made to wine in the Bible. Ancient Islamic alchemists advanced the practice of alcohol production by using distillation techniques. Distilled alcohols began to appear in the Middle Ages and was used in many remedies and medicines. A common practice by alchemists in different regions was the preparation of special liquors and brews with healing power. Aqua vitae (water of life) could refer to brandy, gin, whiskey, wine, or another form of alcoholic depending on the geographic area.

使用

One of the most prominent uses of ethyl alcohol is as a fuel additive and increasingly as a fuel itself. Ethyl alcohol is added to gasoline to increase its oxygen content and octane number. In the United States, the Environmental Protection Agency has mandated that oxygenated fuels be used in certain geographic areas to help meet air quality standards for carbon monoxide, especially in winter. A gasoline blended for this purpose may contain a few percent ethyl alcohol. Gasoline blended with ethyl alcohol is called gasohol. A typical gasohol may contain 90% gasoline and 10% ethanol. Gasohol reduces several common air pollutants including carbon monoxide, carbon dioxide, hydrocarbons, and benzene. Conversely, nitrogen oxides increase with gasohol.

使用

Ethanol is used primarily as a solvent — animportant industrial solvent for resins, lacquers, pharmaceuticals, toilet preparations,and cleaning agents; in the production of rawmaterials for cosmetics, perfumes, drugs, andplasticizers; as an antifreeze; as an automotive fuel additive; and from ancient times, inmaking beverages. Its pathway to the bodysystem is mainly through the consumption ofbeverages. It is formed by the natural fermentation of corn, sugarcane, and other crops.

使用

alcohol (alcohol SD-40; alcohol SDA-40; ethanol; ethyl alcohol) is widely used in the cosmetic industry as an antiseptic as well as a solvent given its strong grease-dissolving abilities. It is often used in a variety of concentrations in skin toners for acne skin, aftershave lotions, perfumes, suntan lotions, and toilet waters. Alcohol dries the skin when used in high concentrations. It is manufactured through the fermentation of starch, sugar, and other carbohydrates.

使用

ethyl alcohol (Etanol) is commonly known as rubbing alcohol. ethyl alcohol is ordinary alcohol and is used medicinally as a topical antiseptic, astringent, and anti-bacterial. At concentrations above 15 percent, it is also a broad-spectrum preservative against bacteria and fungi, and can boost the efficacy of other preservatives in a formulation. Cosmetic companies tend to use alcohol SD-40 in high-grade cosmetic manufacturing as they consider ethanol too strong and too drying for application on the skin. obtained from grain distillation, it can also be synthetically manufactured.

使用

Suitable for use in the precipitation of nucleic acids.

使用

Most ethyl alcohol is used in alcoholic beverages in suitable dilutions. Other uses are as solvent in laboratory and industry, in the manufacture of denatured alcohol, pharmaceuticals (rubbing Compounds, lotions, tonics, colognes), in perfumery, in organic synthesis. Octane booster in gasoline. Pharmaceutic aid (solvent).

定義

ChEBI: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.

定義

A colorless volatile liquid alcohol. Ethanol occurs in intoxicating drinks, in which it is produced by fermentation of a sugar: C6H12O6 → 2C2H5OH + 2CO2 Yeast is used to cause the reaction. At about 15% alcohol concentration (by volume) the reaction stops because the yeast is killed. Higher concentrations of alcohol are produced by distillation. Apart from its use in drinks, alcohol is used as a solvent and to form ethanal. Formerly, the main source was by fermentation of molasses, but now catalytic hydration of ethene is used to manufacture industrial ethanol. See also methylated spirits.

調製方法

Ethanol is manufactured by the controlled enzymatic fermentation of starch, sugar, or other carbohydrates. A fermented liquid is produced containing about 15% ethanol; ethanol 95% v/v is then obtained by fractional distillation. Ethanol may also be prepared by a number of synthetic methods.

brand name

Absolute alcohol;Alcohol aethylicus;Alcool;Avitoin;Banatol;B-tonin;Colfin;Desqyam-x;Duonale-e;Efatin;Equithesin;Hizeneck-d;Honkon-n;Kapsitrin;Keralyt;Levovinizol;Mikrozid;Neotizol;Panoxy;Papette;Piadarn;Polislerol;Protectaderm;Sicol;Sodaphilline;Softa man;Sotracarix;Verucid;Weingeist;Xeracin.

世界保健機関(WHO)

Ethanol has been used throughout recorded history both in a medicinal and a social context. It is currently included in pharmaceutical preparations either as an active or inactive ingredient. At pharmacologically active doses ethanol is both a powerful cerebral depressant and a drug of addiction. Its use in pharmaceutical preparations has been severely restricted in several countries and in 1986 the 39th World Health Assembly adopted a resolution to prohibit such use except when ethanol is an essential ingredient which cannot be replaced by an appropriate alternative.

反応プロフィール

It liberates hydrogen when it reacts withmetal; forms acetaldehyde (toxic, flammable)on catalytic vapor phase dehydrogenation;ethyl ether (flammable) on dehydration withH2SO4 or a heterogeneous catalyst such asalumina, silica, SnCl2, MnCl2, or CuSO4;.

危険性

Classified as a depressant drug. Though it is rapidly oxidized in the body and is therefore noncumulative, ingestion of even moderate amounts causes lowering of inhibitions, often succeeded by dizziness, headache, or nausea. Larger intake causes loss of m

健康ハザード

Exposures to ethyl alcohol by ingestion cause dizziness, faintness, drowsiness, decreased awareness and responsiveness, euphoria, abdominal discomfort, nausea, vomiting, staggering gait, lack of coordination, and coma. Ethyl alcohol causes no adverse effects with normal skin, but is potentially harmful when absorbed across markedly abraded skin. Repeated inhalation of ethyl alcohol vapors in high concentrations may cause a burning sensation in the throat and nose, stinging and watering in the eyes with symptoms of irritation, dizziness, faintness, drowsiness, nausea, and vomiting. Direct exposures of the eyes to ethyl alcohol may cause mild to moderate conjunctivitis, seen mainly as redness of the conjunctiva. Prolonged and repeated oral exposures to ethyl alcohol result in the development of progressive liver injury with fi brosis. Chronic exposures or repeated ingestion of ethyl alcohol by pregnant women are known to adversely affect the CNS of the fetus, producing a collection of effects that together constitute fetal alcohol syndrome. The adverse health effects observed in the fetus include mental and physical retardation, disturbances of learning, motor, and language defi ciencies, small size head, and behavioral disorders. The target organs that are damaged by prolonged exposures to ethyl alcohol include the eyes, skin, respiratory system, CNS, liver, blood, and reproductive system.

健康ハザード

The acute toxicity of ethanol is very low. Ingestion of ethanol can cause temporary nervous system depression with anesthetic effects such as dizziness, headache, confusion, and loss of consciousness; large doses (250 to 500 mL) can be fatal in humans. High concentrations of ethanol vapor are irritating to the eyes and upper respiratory tract. Liquid ethanol does not significantly irritate the skin but is a moderate eye irritant. Exposure to high concentrations of ethanol by inhalation (over 1000 ppm) can cause central nervous system (CNS) effects, including dizziness, headache, and giddiness followed by depression, drowsiness, and fatigue. Ethanol is regarded as a substance with good warning properties. Tests in some animals indicate that ethanol may have developmental and reproductive toxicity if ingested. There is no evidence that laboratory exposure to ethanol has carcinogenic effects. To discourage deliberate ingestion, ethanol for laboratory use is often "denatured" by the addition of other chemicals; the toxicity of possible additives must also be considered when evaluating the risk of laboratory exposure to ethanol

健康ハザード

VAPOR: Irritating to eyes, nose and throat. LIQUID: Not harmful.

健康ハザード

The toxicity of ethanol is much lower thanthat of methanol or propanol. However, theliterature on the subject is vastly greater thanthat of any other alcohol. This is attributableessentially to its use in alcoholic beverages.There are exhaustive reviews on alcohol toxicity and free-radical mechanisms (Nordmannet al. 1987). The health hazard arises primarily from ingestion rather than inhalation. Ingestion of a large dose, 250–500 mL,can be fatal. It affects the central nervoussystem. Symptoms are excitation, intoxication, stupor, hypoglycemia, and coma — thelatter occurring at a blood alcohol contentof 300–400 0 mg/L. It is reported to have atoxic effect on the thyroid gland (Hegeduset al. 1988) and to have an acute hypotensiveaction, reducing the systolic blood pressurein humans (Eisenhofer et al. 1987). Chronicconsumption can cause cirrhosis of the liver.Inhalation of alcohol vapors can result inirritation of the eyes and mucous membranes.This may happen at a high concentrationof 5000–10,000 ppm. Exposure may resultin stupor, fatigue, and sleepiness. There isno report of cirrhosis occurring from inhalation. Chronic exposure to ethanol vapors hasproduced brain damage in mice. The neurotoxicity increases with thiamine deficiency(Phillips 1987). Both acute and chronic dosesof ethanol elevated the lipid peroxidation inrat brain. This was found to be elevated further by vitamin E deficiency, as well as itssupplementation (Nadiger et al. 1988).
pplementation (Nadiger et al. 1988).The toxicity of ethanol is enhanced in thepresence of compounds such as barbiturates,carbon monoxide, and methyl mercury. Withthe latter compound, ethanol enhanced theretention of mercury in the kidney of ratsand thus increased nephrotoxicity (McNeilet al. 1988). When combined with cocaineand fed to rats, increased maternal and fetaltoxicity was observed (Church et al. 1988).Ethanol is reported to be synergisticallytoxic with caffeine (Pollard 1988) andwith n-butanol and isoamyl alcohol. Priorethanol consumption increased the toxicity of acetaminophen in mice (Carter1987).

火災危険

Flash Point (°F): 55 ℃; 64 ℃; Flammable Limits in Air (%): 3.3-19; Fire Extinguishing Agents: Carbon dioxide, dry chemical, water spray, alcohol foam; Fire Extinguishing Agents Not To Be Used: None; Special Hazards of Combustion Products: None; Behavior in Fire: Not pertinent; Ignition Temperature (°F): 689; Electrical Hazard: Class I, Group D; Burning Rate: 3.9 mm/min.

火災危険

FLAMMABLE. Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area.

火災危険

Ethanol is a flammable liquid (NFPA rating = 3), and its vapor can travel a considerable distance to an ignition source and "flash back." Ethanol vapor forms explosive mixtures with air at concentrations of 4.3 to 19% (by volume). Hazardous gases produced in ethanol fires include carbon monoxide and carbon dioxide. Carbon dioxide or dry chemical extinguishers should be used for ethanol fires.

燃焼性と爆発性

Ethanol is a flammable liquid (NFPA rating = 3), and its vapor can travel a considerable distance to an ignition source and "flash back." Ethanol vapor forms explosive mixtures with air at concentrations of 4.3 to 19% (by volume). Hazardous gases produced in ethanol fires include carbon monoxide and carbon dioxide. Carbon dioxide or dry chemical extinguishers should be used for ethanol fires.

化学反応性

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

応用例(製薬)

Ethanol and aqueous ethanol solutions of various concentrations are widely used in pharmaceutical formulations and cosmetics. Although ethanol is primarily used as a solvent, it is also employed as a disinfectant, and in solutions as an antimicrobial preservative. Topical ethanol solutions are used in the development of transdermal drug delivery systems as penetration enhancers. Ethanol has also been used in the development of transdermal preparations as a co-surfactant.

接触アレルゲン

Ethanol is widely used for its solvent and antiseptic properties. It is rather an irritant and sensitization has rarely been reported.

安全性プロファイル

Confirmed human carcinogen for ingestion of beverage alcohol. Experimental tumorigenic and teratogenic data. Moderately toxic to humans by ingestion. Moderately toxic experimentally by intravenous and intraperitoneal routes. Mildly toxic by inhalation and skin contact. Human systemic effects by ingestion and subcutaneous routes: sleep disorders, hallucinations, dtstorted perceptions, convulsions, motor activity changes, ataxia, coma, antipsychotic,headache, pulmonary changes, alteration in gastric secretion, nausea or vomiting, other gastrointestinal changes, menstrual cycle changes, and body temperature decrease. Can also cause glandular effects in humans. Human reproductive effects by ingestion, intravenous, and intrauterine routes: changes in female fertility index. Effects on newborn include: changes in Apgar score, neonatal measures or effects, and drug dependence. Experimental reproductive effects. Human mutation data reported. An eye and skin irritant. The systemic effect of ethanol differs from that of methanol. Ethanol is rapidly oxidtzed in the body to carbon dtoxide and water, and, in contrast to methanol, no cumulative effect occurs. Though ethanol possesses narcotic properties, concentrations sufficient to produce this effect are not reached in industry. Concentrations below 1000 pprn usually produce no signs of intoxication. Exposure to concentrations over 1000 pprn may cause headache, irritation of the eyes, nose, and throat, and, if continued for an hour, drowsiness and lassitude, loss of appetite, and inability to concentrate. There is no concrete evidence that repeated exposure to ethanol vapor results in cirrhosis of the liver. Ingestion of large doses can cause alcohol poisoning. Repeated ingestions can lead to alcoholism. It is a central nervous system depressant.Flammable liquid when exposed to heat or flame; can react vigorously with oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Explosive reaction with the oxidized coating around potassium metal. Ignites and then explodes on contact with acetic anhydride + sodum hydrogen sulfate. Reacts violently with acetyl bromide (evolves hydrogen bromide), dichloromethane + sulfuric acid + nitrate or nitrite, disulfuryl difluoride, tetrachlorosilane + water, and strong oxidants. Ignites on contact with disulfuric acid + nitric acid, phosphorus(IⅡ) oxide, platinum, potassium tert-butoxide + acids. Forms explosive products in reaction with ammonia + silver nitrate (forms silver nitride and silver fulminate), magnesium perchlorate (forms ethyl perchlorate), nitric acid + silver (forms silver fulminate), silver nitrate (forms ethyl nitrate), silverp) oxide + ammonia or hydrazine (forms silver nitride and silver fulminate), sodum (evolves hydrogen gas). Incompatible with acetyl chloride, BrF5, Ca(OCl)2, ClO3, Cr03, Cr(OCl)2, (cyanuric acid + H20), H202, HNO3, (H202 + H2SO4), (I + CH3OH + HgO), wn(ClO4)2 + 2,2-dimethoxy propane], Hg(NO3)2, HClO4, perchlorates, (H2SO4 + permanganates), HMn04, KO2, KOC(CH3)3, AgClO4, NaH3N2, uo2(clO4)2

安全性

Ethanol and aqueous ethanol solutions are widely used in a variety of pharmaceutical formulations and cosmetics. It is also consumed in alcoholic beverages.
Ethanol is rapidly absorbed from the gastrointestinal tract and the vapor may be absorbed through the lungs; it is metabolized, mainly in the liver, to acetaldehyde, which is further oxidized to acetate.
Ethanol is a central nervous system depressant and ingestion of low to moderate quantities can lead to symptoms of intoxication including muscle incoordination, visual impairment, slurred speech, etc. Ingestion of higher concentrations may cause depression of medullary action, lethargy, amnesia, hypothermia, hypoglycemia, stupor, coma, respiratory depression, and cardiovascular collapse. The lethal human blood-alcohol concentration is generally estimated to be 400–500 mg/100 mL.
Although symptoms of ethanol intoxication are usually encountered following deliberate consumption of ethanol-containing beverages, many pharmaceutical products contain ethanol as a solvent, which, if ingested in sufficiently large quantities, may cause adverse symptoms of intoxication. In the USA, the maximum quantity of alcohol included in OTC medicines is 10% v/v for products labeled for use by people of 12 years of age and older, 5% v/v for products intended for use by children aged 6–12 years of age, and 0.5% v/v for products for use by children under 6 years of age.
Parenteral products containing up to 50% of alcohol (ethanol 95 or 96% v/v) have been formulated. However, such concentrations can produce pain on intramuscular injection and lower concentrations such as 5–10% v/v are preferred. Subcutaneous injection of alcohol (ethanol 95% v/v) similarly causes considerable pain followed by anesthesia. If injections are made close to nerves, neuritis and nerve degeneration may occur. This effect is used therapeutically to cause anesthesia in cases of severe pain, although the practice of using alcohol in nerve blocks is controversial. Doses of 1mL of absolute alcohol have been used for this purpose.
Preparations containing more than 50% v/v alcohol may cause skin irritation when applied topically.
LD50 (mouse, IP): 0.93 g/kg
LD50 (mouse, IV): 1.97 g/kg
LD50 (mouse, oral): 3.45 g/kg
LD50 (mouse, SC): 8.29 g/kg
LD50 (rat, IP): 3.75 g/kg
LD50 (rat, IV): 1.44 g/kg
LD50 (rat, oral): 7.06 g/kg

職業ばく露

Ethyl alcohol is used, topical antiinfective agent; solvent to make beverages; in the chemical synthesis of a wide variety of compounds, such as acetaldehyde, ethyl ether, ethyl chloride, and butadiene. It is a solvent or processing agent in the manufacture of pharmaceuticals; plastics, lacquers, polishes, plasticizers, perfumes, cosmetics, rubber accelerators; explosives, synthetic resins; nitrocellulose, adhesives, inks, and preservatives. It is also used as an antifreeze and as a fuel. It is an intermediate in the manufacture of many drugs and pesticides.

応急処置

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit

貯蔵

Ethyl alcohol should be protected from physical damage. It should be kept stored in a cool, dry, well-ventilated location, away from any area where the fi re hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfer to avoid static sparks. The storage and use areas should be free from smoking areas.

貯蔵

Aqueous ethanol solutions may be sterilized by autoclaving or by filtration and should be stored in airtight containers, in a cool place.

輸送方法

UN1170 Ethyl alcohol or Ethanol or Ethanol solutions or Ethyl alcohol solutions, Hazard Class: 3; Labels: 3-Flammable liquid.

純化方法

Usual impurities of fermentation alcohol are fusel oils (mainly higher alcohols, especially pentanols), aldehydes, esters, ketones and water. With synthetic alcohol, likely impurities are water, aldehydes, aliphatic esters, acetone and diethyl ether. Traces of *benzene are present in ethanol that has been dehydrated by azeotropic distillation with *benzene. Anhydrous ethanol is very hygroscopic. Water (down to 0.05%) can be detected by formation of a voluminous precipitate when aluminium ethoxide in *benzene is added to a test portion, Rectified spirit (95% ethanol) is converted to absolute (99.5%) ethanol by refluxing with freshly ignited CaO (250g/L) for 6hours, standing overnight and distilling with precautions to exclude moisture. Numerous methods are available for further drying of absolute ethanol for making “Super dry ethanol”. Lund and Bjerrum [Chem Ber 64 210 1931] used reaction with magnesium ethoxide, prepared by placing 5g of clean dry magnesium turnings and 0.5g of iodine (or a few drops of CCl4), to activate the Mg, in a 2L flask, followed by 50-75 mL of absolute ethanol, and warming the mixture until a vigorous reaction occurs. When this subsides, heating is continued until all the magnesium is converted to magnesium ethoxide. Up to 1L of ethanol is then added and, after an hour's reflux, it is distilled off. The water content should be below 0.05%. Walden, Ulich and Laun [Z Phys Chem 114 275 1925] used amalgamated aluminium chips, prepared by degreasing aluminium chips (by washing with Et2O and drying in a vacuum to remove grease from machining the Al), treating with alkali until hydrogen evolved vigorously, washing with H2O until the washings were weakly alkaline and then stirring with 1% HgCl2 solution. After 2minutes, the chips were washed quickly with H2O, then alcohol, then ether, and dried with filter paper. (The amalgam became warm.) These chips were added to the ethanol, which was then gently warmed for several hours until evolution of hydrogen ceased. The alcohol was distilled and aspirated for some time with pure dry air. Smith [J Chem Soc 1288 1927] reacted 1L of absolute ethanol in a 2L flask with 7g of clean dry sodium, and added 25g of pure ethyl succinate (27g of pure ethyl phthalate was an alternative), and refluxed the mixture for 2hours in a system protected from moisture, and then distilled the ethanol. A modification used 40g of ethyl formate instead, so that sodium formate separated out and, during reflux, the excess of ethyl formate decomposed to CO and ethanol. Drying agents suitable for use with ethanol include Linde type 4A molecular sieves, calcium metal, and CaH2. The calcium hydride (2g) is crushed to a powder and dissolved in 100mL absolute ethanol by gently boiling. About 70mL of the ethanol are distilled off to remove any dissolved gases before the remainder is poured into 1L of ca 99.9% ethanol in a still, where it is boiled under reflux for 20hours, while a slow stream of pure, dry hydrogen (better use nitrogen or Ar) is passed through. It is then distilled [Rüber Z Elektrochem 29 334 1923]. If calcium is used for drying, about ten times the theoretical amount should be used, and traces of ammonia (from some calcium nitride in the Ca metal) would be removed by passing dry air into the vapour during reflux. Ethanol can be freed from traces of basic materials by distillation from a little 2,4,6-trinitrobenzoic acid or sulfanilic acid. *Benzene can be removed by fractional distillation after adding a little water (the *benzene/water/ethanol azeotrope distils at 64.9o), the alcohol is then re-dried using one of the methods described above. Alternatively, careful fractional distillation can separate *benzene as the *benzene/ethanol azeotrope (b 68.2o). Aldehydes can be removed from ethanol by digesting with 8-10g of dissolved KOH and 5-10g of aluminium or zinc per L, followed by distillation. Another method is to heat under reflux with KOH (20g/L) and AgNO3 (10g/L) or to add 2.5-3g of lead acetate in 5mL of water to 1L of ethanol, followed (slowly and without stirring) by 5g of KOH in 25mL of ethanol: after 1hour the flask is shaken thoroughly, then set aside overnight before filtering and distilling. The residual water can be removed by standing the distillate over activated aluminium amalgam for 1 week, then filtering and distilling. Distillation of ethanol from Raney nickel eliminates catalyst poisons. Other purification procedures include pre-treatment with conc H2SO4 (3mL/L) to eliminate amines, and with KMnO4 to oxidise aldehydes, followed by refluxing with KOH to resinify aldehydes, and distilling to remove traces of H3PO4 and other acidic impurities after passage through silica gel, and drying over CaSO4. Water can be removed by azeotropic distillation with dichloromethane (azeotrope boils at 38.1o and contains 1.8% water) or 2,2,4-trimethylpentane. [Beilstein 1 IV 1289.] Rapid purification: Place degreased Mg turnings (grease from machining the turnings is removed by washing with dry EtOH then Et2O, and drying in a vacuum) (5g) in a dry 2L round bottomed flask fitted with a reflux condenser (protect from air with a drying tube filled with CaCl2 or KOH pellets) and flush with dry N2. Then add iodine crystals (0.5g) and gently warm the flask until iodine vapour is formed and coats the turnings. Cool, then add EtOH (50mL) and carefully heat to reflux until the iodine disappears. Cool again then add more EtOH (to 1L) and reflux under N2 for several hours. Distil and store over 3A molecular sieves (pre-heated at

不和合性

May form explosive mixture with air. May accumulate static electrical charges, and may cause ignition of its vapors. Reactions may be violent with oleum, sulfuric acid; nitric acid, bases, aliphatic amines;isocyanates, strong oxidizers. Also incompatible with potassium dioxide, bromine pentafluoride; acetyl bromide; acetyl chloride; platinum, sodium.

不和合性

In acidic conditions, ethanol solutions may react vigorously with oxidizing materials. Mixtures with alkali may darken in color owing to a reaction with residual amounts of aldehyde. Organic salts or acacia may be precipitated from aqueous solutions or dispersions. Ethanol solutions are also incompatible with aluminum containers and may interact with some drugs.

廃棄物の処理

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

予防処置

During handling of ethyl alcohol, workers should use chemical-resistant shields, monogoggles, proper gloves, laboratory coat/apron, and protective equipment as required. Workers and the workplace should have adequate ventilation vent hoods, class b extinguisher. Workers should avoid sources of heat, sparks, or flames. Waste disposal and spill should be collected in suitable containers or absorbed on a suitable absorbent material for subsequent disposal. Waste material should be disposed of in an approved incinerator or in a designated landfi ll site, in compliance with all federal, provincial, and local government regulations.

規制状況(Regulatory Status)

Included in the FDA Inactive Ingredients Database (dental preparations; inhalations; IM, IV, and SC injections; nasal and ophthalmic preparations; oral capsules, solutions, suspensions, syrups, and tablets; rectal, topical, and transdermal preparations). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in nonparenteral and parenteral medicines licensed in the UK.

エタノール 上流と下流の製品情報

原材料

準備製品


エタノール 生産企業

Global( 375)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1730 55
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20331 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939
021-51821727 shenlinxing@macklin.cn China 15724 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 sale@aladdin-e.com China 24991 65
Spectrum Chemical Manufacturing Corp. 021-67601398,18616765336,QQ:3003443155
021-57711696 mkt@spectrumchina.net China 9692 60

64-17-5(エタノール)キーワード:


  • 64-17-5
  • ALCOHOL, SDA 3C
  • ETHANOL ABSOLUTE DVH
  • 1-hydroxyethane
  • Absolute ethanol
  • absoluteethanol
  • absoluterAlkohol
  • Aethanol
  • Aethylalkohol
  • Alcare Hand Degermer
  • Alcohol anhydrous
  • Alcohol, dehydrated
  • Alcohol, diluted
  • alcohol,[combustiblelabel]
  • alcohol,anhydrous
  • alcohol,ethyl
  • alcoholanhydrous
  • spiritsofwine
  • Spirt
  • Synasol
  • Tecsol
  • Tecsol C
  • tecsolc
  • Thanol
  • USI in oval
  • Weingeist
  • Alcohol absolute
  • Ethanol95%
  • Ethyl alcohol 95%
  • Edible ethanol
  • ETHANOL REAGENT ANHYDROUS DENATURED
  • 消毒用エタライト
  • オー消エタ
  • テクソール
  • 消エタサラコール
  • アルコール
  • 消毒用エタノールα
  • 消毒用エタノール
  • 酒精
  • メチルカルビノール
  • 純生局エタ
  • 水和エチル
  • エチルアルコール
  • 消毒用エタIP
  • 消エタコア
  • 純生消エタ
  • 消毒用エタライト-B
  • エタン-1-オール
  • 消毒用エタノールIPA
  • エコ消エタ
  • エタノール
  • 消毒用エタプロコール
  • 消毒用エタノールFG
  • 消毒用エタプロコール-U
  • エタノ-ル
  • エタノール CRM4001-A
  • エタノール(99.5)
  • エタノール(脱水)
  • エタノル
  • 変性アルコール
  • 局方エタノール
  • 局方無水エタノール
  • 局方消毒エタノール
  • 無水エタノール
  • エタノール CRM4001‐B
  • エタノール(95)
  • エタノール標準原液
  • 無水エタノール(UE)
  • エタノール (95%)エチルアルコール (95%)
  • エタノール (99.5%)エチルアルコール (99.5%)
  • エタノール (99.5)
  • エタノール ABSOLUTE エタノール,DENATURATED WITH 4.8% メタノール,A15 METHYL 1 ,≥99.8% (BASED ON DENATURANT-FREE SUBSTANCE)
  • エタノール ABSOLUTE,≥99.8% (GC)
  • エタノール ABSOLUTE,DENATURATED WITH 0.5-1.5 VOL.% 2-ブタノン AND APPROX. 0.001% BITREX (GC),≥98% (GC)
  • エタノール ABSOLUTE,REAG. ISO,REAG. PH. EUR.,≥99.8% (GC),LIQUID (CLEAR,COLORLESS)
  • エタノール PURISS. P.A.,ABSOLUTE,≥99.8% (GC)
  • エタノール PURISS.,MEETS ANALYTICAL SPECIFICATION OF PH.EUR.,BP,96.0-97.2%
  • エタノール PURUM,FINE SPIRIT,WITHOUT ADDITIVE,F25 O1,~96%
  • エタノール SOLUTION TESTED ACCORDING TO PH.HELV.,70 % (V/V) IN H2O
  • エタノール,ABSOLUTE,DENATURATED WITH 1%
  • エチルアルコール,PURE 200 PROOF,ACS REAGENT,≥99.5%
  • エチルアルコール,PURE 200 PROOF,FOR MOLECULAR BIOLOGY
  • エチルアルコール,PURE 200 PROOF,HPLC/SPECTROPHOTOMETRIC GRADE
  • エチルアルコール,PURE 200 PROOF,MEETS USP TESTING SPECIFICATIONS
  • IPA変性アルコール 95%
  • IPA変性アルコール 99%
  • IPA変性エタノー
  • エチルアルコール(99.5)
  • メタ変性アルコール 95%
  • メタ変性アルコール 99%
  • メタ変性エタノー
  • エタノール(95V/V%)
  • エタノール(99.5V/V%)
  • エタノール (95)
  • エタノール「製造専用」
  • エタノールスプレー
  • 組織脱水溶液 99
  • エタノール 溶液
  • 無水エタノール (JP17)
  • 溶媒
  • 殺菌薬
  • 外皮作用薬
  • 中枢抑制薬
Copyright 2017 © ChemicalBook. All rights reserved