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Cefoselis sulfate

 化学構造式
122841-12-7
CAS番号.
122841-12-7
化学名:
别名:
英語化学名:
Cefoselis sulfate
英語别名:
Winsef;FK 037;FK 037 Sulfate;CEFOSELIS SULFATE;(6R,7R,E)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydropyrazol-1-yl)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, sulfate;(6R-(6alpha,7beta(Z)))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid sulfate
CBNumber:
CB4263737
化学式:
C19H24N8O10S3
分子量:
620.64
MOL File:
122841-12-7.mol

Cefoselis sulfate 物理性質

CAS データベース:
122841-12-7(CAS DataBase Reference)

安全性情報

Cefoselis sulfate 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Cefoselis sulfate 化学特性,用途語,生産方法

説明

Cefoselis is a new fourth-generation cephalosporin and was launched in Japan as a parenteral antibiotic for a variety of infections including Staphylococcus aureus (particularly the methicillin-resistant MRSA) and Pseudornonas aeruginosa. It can be prepared in 3 related ways, all using 2- pyrazolomethyl-3-cephem-4-carboxylic as the key intermediate. In preclinical studies, Cefolesis had better MIC50s than Ceftazidime against Streptococcus pneurnoniae or Staphflococcus aureus (methicillin-sensitive MSSA or resistant MRSA) and showed significant antibacterial activity against Citrobacter and Enterobacter.
Cefolesis is well tolerated in clinical studies, being eliminated mainly via glomerular filtration in humans.

Originator

Fujisawa (Japan)

使用

antibiotic

brand name

Wincef

Cefoselis sulfate 上流と下流の製品情報

原材料

準備製品


Cefoselis sulfate 生産企業

Global( 95)Suppliers
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122841-12-7()キーワード:


  • 122841-12-7
  • (6R-(6alpha,7beta(Z)))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid sulfate
  • Winsef
  • CEFOSELIS SULFATE
  • FK 037
  • (6R,7R,E)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydropyrazol-1-yl)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, sulfate
  • FK 037 Sulfate
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