3-アミノ-p-トルイル酸 メチル
3-アミノ-p-トルイル酸 メチル 物理性質
- 融点 :
- 113-117 °C(lit.)
- 沸点 :
- 296.3±20.0 °C(Predicted)
- 比重(密度) :
- 1.132±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- Keep in dark place,Inert atmosphere,Room temperature
- 溶解性:
- クロロホルム（微量）、メタノール（微量）
- 酸解離定数(Pka):
- 3.31±0.10(Predicted)
- 外見 :
- 結晶性粉末
- 色:
- ホワイト～クリーム
- BRN :
- 2088611
- InChIKey:
- YEPWCJHMSVABPQ-UHFFFAOYSA-N
- LogP:
- 1.7 at 22℃ and pH7
- CAS データベース:
- 18595-18-1(CAS DataBase Reference)
3-アミノ-p-トルイル酸 メチル 価格
もっと(21)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBOS-1085 |
3-アミノ-4-メチル安息香酸メチル
Methyl 3-amino-4-methylbenzoate |
18595-18-1 |
5g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBOS-1085 |
3-アミノ-4-メチル安息香酸メチル
Methyl 3-amino-4-methylbenzoate |
18595-18-1 |
25g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01AFAA15348 |
3-アミノ-4-メチル安息香酸メチル
Methyl 3-Amino-4-methylbenzoate |
18595-18-1 |
5g |
￥10620 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01AFAA15348 |
3-アミノ-4-メチル安息香酸メチル
Methyl 3-Amino-4-methylbenzoate |
18595-18-1 |
25g |
￥36780 |
2024-03-01 |
購入 |
|
東京化成工業
|
A1432 |
3-アミノ-4-メチル安息香酸メチル >98.0%(GC)
Methyl 3-Amino-4-methylbenzoate
>98.0%(GC) |
18595-18-1 |
25g |
￥6900 |
2024-03-01 |
購入 |
3-アミノ-p-トルイル酸 メチル 化学特性,用途語,生産方法
外観
白色～灰色～褐色粉末～結晶
説明
Methyl 3-amino-4-methylbenzoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
化学的特性
Beige powder
使用
Methyl 3-Amino-4-methylbenzoate is used as a reagent in the synthesis of perfluoroalkylated indoles which are very useful in drug development. It was also used in the preparation of 4-(pyrimidin-2-ylamino) benzamide derivatives which are designed as inhibitors of hedgehog signalling pathway (target of cancer treatment).
主な応用
Methyl 3-amino-4-methylbenzoate can be used for:
To prepare the methyl 4-methyl-3-((4-(proparg-1-yloxy)benzyl)amino)benzoate, 4-proparg-1-yloxybenzaldehyde (16) and methyl 3-amino-4-methylbenzoate were reacted according to the method IA.
Synthesis of Methyl 4-methyl-3-((4-(2-methylthiazol-4-yl)benzoyl)amino)benzoate
Synthesis of 4-Methyl-3-((4-(2-methylthiazol-4-yl)benzoyl)amino)benzamide
Synthesis of methyl 3-(4-hydroxy-6-methyl-2-oxopyridin-1 (2H)-yl)-4-methylbenzoate
Synthesis of (5-Carbomethoxy-2-methylphenyl)(4-hydroxypheny)diazene: To a solution of 6N HC1 (6 mL) was added methyl 3-amino-4-methylbenzoate (1.62 g, 10.0 mmol). The solution was cooled in an ice-bath, and was diazotized by adding sodium nitrite (0.9 g, 12.0 mmol). To a cold solution of phenol in 21% aqueous NaOH solution (6 mL) was added diazotized solution slowly. After 20 min, the solution was acidfied by adding 4 N aqueous HC1 and was poured into the cold water, filtered, and washed with water. Recrystallization from ethanol gave the product (2.0 g, 74%) as red crystals, mp 181.3-182.2 °C.
製造方法
Synthesis of Methyl 3-amino-4-methylbenzoate: Nitro ester Methyl 4-methyl-3-nitrobenzoate (80 g, 0.410 mol) was subjected to hydrogenation in a Parr shaker in MeOH using Raney Ni as the catalyst (5 g, 20 mol %) at 50 psi for 8 hours. The catalyst was filtered off, washed thoroughly with MeOH and the combined filtrates concentrated under reduced pressure to furnish a yellow solid (65.0 g). Yield : 96% Mp : 114-5°C (lit.14 Mp 116°C)
3-アミノ-p-トルイル酸 メチル 上流と下流の製品情報
原材料
準備製品
3-アミノ-p-トルイル酸 メチル 生産企業
Global( 375)Suppliers
3-アミノ-p-トルイル酸 メチル スペクトルデータ(1HNMR、13CNMR、IR1、IR2、MS)
18595-18-1(3-アミノ-p-トルイル酸 メチル)キーワード:
- 18595-18-1
- METHYL 3-AMINO-4-METHYLBENZOATE
- METHYL 3-AMINO-P-TOLUATE
- LABOTEST-BB LT00848257
- 3-Amino-p-Toluic Acid Methyl Ester 3-Amino-4-Methyl Benzoic Acid Methyl Ester
- 3-Amino-4-Methylbenzoate
- 3-Amino-p-toluic
- Methyl 3-amino-4-methylbenzoate 98%
- Methyl 3-Amion-4-Methylbenzoate
- AKOS BB-3092
- 3-AMINO-4-METHYLBENZOIC ACID METHYL ESTER
- 3-AMINO-P-TOLUIC ACID METHYL ESTER
- Methyl4-Methyl-3-Aminobenzoate
- Methyl 3-amino-4-met
- 3-Amino-4-methylbenzoic Acid Methyl Ester
Methyl 3-Amino-p-toluate
3-Amino-p-toluic Acid Methyl Ester
- Methyle3-amino-4-methylbenzoate
- 5-(Methoxycarbonyl)-2-methylaniline, 2-Amino-4-(methoxycarbonyl)toluene, 5-(Methoxycarbonyl)-o-toluidine
- Benzoic acid, 3-aMino-4-Methyl-, Methyl ester
- Methyl-3-amino-4-methylbenozate
- 3-amino-2,4-dimethylbenzoate
- Nilotinib Impurity 25
- Nilotinib EP Impurity B
- Methyl 3-Amino-4-methylbenzoate >
- Methyl 3-amino-4-methylbenzoate 18595-18-1
- Nilotinib USP Related Compound B
- Benzoic acid, 3-amino-4-methyl-, methyl ester (9CI, ACI)
- 3-amino-4-methyl-Benzoic acid methyl ester (9CI ACI)
- Compound Fr13901
- Nilotinib Hydrochloride Monohydrate EP Impurity B
- Nilotinib Impurity 17(Nilotinib EP Impurity B)
- 3-アミノ-p-トルイル酸 メチル
- 3-アミノ-4-メチル安息香酸メチル
- 3-アミノ-p-トルイル酸メチル
- 3‐アミノ‐4‐メチル安息香酸メチル