(4-Fluorophenyl)acetone

(4-Fluorophenyl)acetone 구조식 이미지
카스 번호:
459-03-0
상품명:
(4-Fluorophenyl)acetone
동의어(영문):
cas 459-03-0;2-Propanone, 1-(4;4-FLUOROPHENYLACETONE;4'-FLUOROPHENYLACETONE;(P-FLUOROPHENYL)ACETONE;4-Fluorophenylacetone98%;4-Fluorophenylacetone 98%;4-Fluorophenylacetone,99%;1-(4-Fluorophenyl)acetone;4-Fluorophenylacetone pmk
CBNumber:
CB0459004
분자식:
C9H9FO
포뮬러 무게:
152.17
MOL 파일:
459-03-0.mol
MSDS 파일:
SDS

(4-Fluorophenyl)acetone 속성

끓는 점
106-107 °C/18 mmHg (lit.)
밀도
1.139 g/mL at 25 °C (lit.)
굴절률
n20/D 1.496(lit.)
인화점
197 °F
저장 조건
Sealed in dry,Room Temperature
용해도
Methyl Acetate: 50 mg/ml
물리적 상태
투명한 액체
색상
Light yellow to Yellow to Orange
Specific Gravity
1.139
수용성
불용성
BRN
1936697
InChI
InChI=1S/C9H9FO/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5H,6H2,1H3
InChIKey
ZUEKIIWSVFBTCM-UHFFFAOYSA-N
SMILES
C(C1=CC=C(F)C=C1)C(=O)C
CAS 데이터베이스
459-03-0(CAS DataBase Reference)
NIST
(4-Fluorophenyl)acetone(459-03-0)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 F,Xi
위험 카페고리 넘버 36/37/38
안전지침서 24/25
WGK 독일 3
위험 참고 사항 Flammable
위험 등급 IRRITANT, FLAMMABLE
HS 번호 29147090
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H227 가연성 액체 인화성 액체 구분 4 경고 P210, P280, P370+P378, P403+P235,P501
예방조치문구:
P210 열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P403+P235 환기가 잘 되는 곳에 보관하고 저온으로 유지하시오.
P501 ...에 내용물 / 용기를 폐기 하시오.
NFPA 704
2
0 0

(4-Fluorophenyl)acetone MSDS


4-Fluorophenylacetone

(4-Fluorophenyl)acetone C화학적 특성, 용도, 생산

개요

This intermediate, also known as (4-Fluorophenyl)acetone, presents as a dark yellow liquid. It is known to be insoluble in water. For best results, store in a tightly closed container in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 4-Fluorophenylacetone is incompatible with strong oxidizing agents. This chemical is a combustible liquid.

화학적 성질

clear yellow liquid

용도

4-Fluorophenylacetone is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It is a haloarylacetone derivative used in a study of reversed enantiopreference of an ω-transaminase by a single-point mutation.

주요 응용

(4-Fluorophenyl)acetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors. It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor. (4-Fluorophenyl)acetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis. Brevibacterium sp. strain P7 was used as a model system and it has found that it inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.

(4-Fluorophenyl)acetone 준비 용품 및 원자재

원자재

준비 용품


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