2-(4-이소부틸페닐)프로피온알데히드
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2-(4-이소부틸페닐)프로피온알데히드 속성
- 끓는 점
- 64-65 °C(Press: 0.2 Torr)
- 밀도
- 0.937±0.06 g/cm3(Predicted)
- 저장 조건
- Hygroscopic, Refrigerator, under inert atmosphere
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 기름
- 색상
- 무색
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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2-(4-이소부틸페닐)프로피온알데히드 C화학적 특성, 용도, 생산
용도
2-(4-Isobutylphenyl)propanal is an impurity of the drug Ibuprofen (I140000), a selective cyclooxygenase inhibitor that also inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.생산 방법
Numerous methods are known for the synthesis of 2-(4-isobutylphenyl)propionaldehyde. It can be prepared by reaction of p-isobutylacetophenone with methyl chloroacetate using sodium methoxide as catalyst, followed by reaction of the glycidic ester with BF3 to give 2- hydroxy-3-(4-isobutylphenyl)-3-butenoic acid methyl ester, which is subsequently treated with mineral acid Avariant of the process is the hydrolysis of the intermediately formed glycidic ester with alkali to give the corresponding salt of glycidic acid, which is then decarboxylated. In addition, 2-(4-isobutylphenyl)propanal is formed by isomerization of 2-(4-isobutylphenyl)- 2-methyloxirane on Al2O3-SiO2 or anhydrous ZnCl2, by reaction of 1-(4-isobutylphenyl)- 1-chloroethane with dimethylformamide in the presence of Li or Na in tetrahydrofuran, and in good yields by Rh- or Co-catalyzed hydroformylation of p-isobutylstyrene.2-(4-이소부틸페닐)프로피온알데히드 준비 용품 및 원자재
원자재
준비 용품
2-(4-이소부틸페닐)프로피온알데히드 공급 업체
글로벌( 38)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 |
1015@dideu.com | China | 4088 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15394 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 |
overseasales@yongstandards.com | China | 11927 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
Adamas Reagent, Ltd. | 400-6009262 16621234537 |
chenyj@titansci.com | China | 14104 | 59 |
SynAsst Chemical. | 021-60343070 |
China | 12742 | 55 | |
Bide Pharmatech Ltd. | 400-164-7117 13681763483 |
product02@bidepharm.com | China | 41463 | 60 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 |
sales@chem-strong.com | China | 18021 | 56 |
2-(4-이소부틸페닐)프로피온알데히드 관련 검색:
페닐 아세트알데히드 이부프로펜
1-Hydroxyibuprofen
Ibuprofen Isopropyl Ester
1-Oxo Ibuprofen
Ibuprofen Ethyl Ester
1,3-bis(4-isobutylphenyl)butan-1-one
2-(4-Methylphenyl)propanoic acid
Ibuprofen Ester Impurity
Ibuprofen Impurity 4
4'-(2-Methylpropyl)acetophenone
4-(2-Methylpropyl)benzeneethanol
4-Benzyloxybenzaldehyde
Ibuprofen EP Impurity I
3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID
Ibuprofen Impurity 2
CARBOXYIBUPROFEN
p-Isobutylstyrene