Glucagon Receptor Antagonist I

Glucagon Receptor Antagonist I 구조식 이미지
카스 번호:
438618-32-7
상품명:
Glucagon Receptor Antagonist I
동의어(영문):
hGCGR Antagonist;Glucagon Receptor Antagonist I;Butanamide, N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-;N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-ethylbutanamide
CBNumber:
CB23136786
분자식:
C20H30N2OS
포뮬러 무게:
346.53
MOL 파일:
438618-32-7.mol

Glucagon Receptor Antagonist I 속성

끓는 점
517.8±50.0 °C(Predicted)
밀도
1.07±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO: 용해될 수 있다
물리적 상태
백색 결정성 고체.
산도 계수 (pKa)
13.46±0.40(Predicted)

안전

Glucagon Receptor Antagonist I C화학적 특성, 용도, 생산

개요

Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.

Glucagon Receptor Antagonist I 준비 용품 및 원자재

원자재

준비 용품


Glucagon Receptor Antagonist I 공급 업체

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