METHACHOLINE CHLORIDE
|
|
METHACHOLINE CHLORIDE 속성
- 녹는점
- 171-173 °C(lit.)
- 밀도
- 1.1028 (rough estimate)
- 굴절률
- 1.5790 (estimate)
- 저장 조건
- -20°C
- 용해도
- H2O: 50 mg/mL, 투명, 무색
- 물리적 상태
- 가루
- 색상
- 흰색에서 거의 흰색
- 수소이온지수(pH)
- 3.0～7.0 (50g/l, 25℃)
- 수용성
- 거의 투명함
- Merck
- 14,5940
- BRN
- 4162373
- 안정성
- 불안정 - 습기에 민감함. 산화제와 호환되지 않습니다.
- LogP
- -3.957 (est)
- CAS 데이터베이스
- 62-51-1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | BR5250000 | ||
| F 고인화성물질 | 3-10-21 | ||
| HS 번호 | 29239000 |
METHACHOLINE CHLORIDE C화학적 특성, 용도, 생산
화학적 성질
colourless to white crystalline powder with a slight용도
antihypertensive, antianginal일반 설명
Methacholine chloride occurs as colorless or white crystalsor as a white crystalline powder. It is odorless or has aslight odor and is very deliquescent. It is freely soluble inwater, alcohol, or chloroform, and its aqueous solution isneutral to litmus and bitter. It is hydrolyzed rapidly in alkalinesolutions. Solutions are relatively stable to heat and willkeep for at least 2 or 3 weeks when refrigerated to delaygrowth of molds.Clinical Use
Methacholine, acetyl β-methylcholine, is marketed as the racemic mixture. It is a selective muscarinic agonist with very little activity at nicotinic receptors. Although methacholine chloride is marketed as the racemic mixture, the S-(+)-enantiomer is 240-fold more potent than the R-(–)-isomer at muscarinic receptors. In addition, AChE hydrolyzes S-(+)–methacholine at approximately 54% the rate of acetylcholine, whereas the R-(–)–enantiomer is a weak inhibitor. Methacholine chloride is used via inhalation for the diagnosis of asthma. The resulting bronchospasm may be relieved with bronchodilators. Methacholine chloride is available as a powder that is reconstituted for inhalation.Purification Methods
It forms white hygroscopic needles from Et2O and is soluble in H2O, EtOH and CHCl3. It decomposes readily in alkaline solutions and slowly in H2O. It should be handled and stored in a dry atmosphere. The bromide is less hygroscopic, and the picrate has m 129.5-131o (from EtOH). [racemate: Annis & Ely Biochem J 53 34 1953, IR of iodide: Hansen Acta Chem Scand 13 155 1959, Beilstein 4 IV 1670.]METHACHOLINE CHLORIDE 준비 용품 및 원자재
원자재
준비 용품
METHACHOLINE CHLORIDE 공급 업체
글로벌( 170)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24099 | 58 |
| Alfa Chemistry | |
info@alfa-chemistry.com | United States | 2344 | 58 |
| Aston Chemical | 13000000000 |
sales@astonchem.com | United States | 1634 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 50003 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40068 | 58 |
METHACHOLINE CHLORIDE 관련 검색:
2-하이드록시-N,N,N-트리메틸에탄아미늄 염화콜린
ACETYL-D-CARNITINE CHLORIDE
Palmitoyl-L-Carnitine Chloride
METHACHOLINE CHLORIDE
O-Acetyl-L-carnitine hydrochloride
(+/-)-OCTANOYLCARNITINE CHLORIDE
BUTYRYL-L-CARNITINE CHLORIDE
β-Methylcholine Chloride
MYRISTOYL-DL-CARNITINE CHLORIDE
PALMITOYL-DL-CARNITINE CHLORIDE
BICUCULLINE METHYLCHLORIDE (-), [METHYL-3H]
(-)-BICUCULLINE METHOCHLORIDE
DL-DECANOYLCARNITINE CHLORIDE
DL-LAUROYLCARNITINE CHLORIDE
(+/-)-PROPIONYLCARNITINE CHLORIDE
ACETYL-DL-CARNITINE HYDROCHLORIDE
DL-STEAROYL CARNITINE CHLORIDE