트리포스겐
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트리포스겐 속성
- 녹는점
- 79-83 °C (lit.)
- 끓는 점
- 203-206 °C (lit.)
- 밀도
- 1.78
- 증기압
- 16 hPa (90 °C)
- 인화점
- 203-206°C
- 저장 조건
- 2-8°C
- 용해도
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- 물리적 상태
- 결정질 분말, 결정 및/또는 덩어리
- 색상
- 흰색에서 황백색까지
- 수용성
- 실질적으로 불용성
- 감도
- Moisture Sensitive
- BRN
- 1787583
- InChIKey
- UCPYLLCMEDAXFR-UHFFFAOYSA-N
- CAS 데이터베이스
- 32315-10-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T+,Xn,T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 26-34-29-36/37/38-20/21/22-23/24/25 | ||
| 안전지침서 | 36/37/39-45-9-26-36-7/9 | ||
| 유엔번호(UN No.) | UN 2928 6.1/PG 2 | ||
| WGK 독일 | 2 | ||
| F 고인화성물질 | 10-19-21 | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | II | ||
| HS 번호 | 29209010 | ||
| 기존화학 물질 | 2003-3-2501 |
트리포스겐 C화학적 특성, 용도, 생산
용도
1.살충제 사항 : 이것은 insectide과 제초제의 생산에 사용할 수 있습니다. 2 의약 : 의학 및 중간체 의약품 또는 염화 아실, 할로겐화물, 알데히드 및 니트릴레 특별 제작에 사용합니다. 3.폴리메러재료 : 그것은 만드는 폴리머와 접착에 사용할 수 있고 그것도 맛 첨가제, 염료, 코팅 및 음료에 적용합니다.개요
Triphosgene is also known as solid phosgene. Its chemical name is bis (Trichloromethyl) carbonate, and its English name is bisgriehloromethyl) carbonate or triphosgene, abbreviated as BTC. Triphosgene is a white crystal, similar to the smell of phosgene. It is mainly used to synthesize chloroformate, isocyanate, polycarbonate and acyl chloride. It is widely used as an intermediate in plastics, medicine, herbicides and pesticides.화학적 성질
White solid용도
Triphosgene is used as a carbonylating agent for aza-peptide synthesis. It reacts with several alfa-amino acids to give the corresponding N-carboxyanhydrides. It is involved in the preparation of the esterification coupling reagent, di-2-thienyl carbonate from 2(5H)-thiophenone. Further, it is used as a reagent in organic synthesis and converts an amino group into isocyanate. In addition to this, it is employed in the preparation of 2-chloronicotinaldehydes through cyclization of the corresponding enamides. It is considered as a useful substitute for phosgene.일반 설명
Triphosgene [Bis(trichloromethyl)carbonate] is a versatile organic reagent used in organic synthesis alternative to phosgene. A catalytic amount of triphosgene is particularly used in chloroformylations, carbonylations, chlorinations, and dehydration reactions.Synthesis
Triphosgene is synthesized by exhaustive free radical chlorination of dimethyl carbonate:CH3OCO2CH3 + 6 Cl2 → CCl3OCO2CCl3 + 6 HCl
Triphosgene can be easily recrystallized from hot hexanes.
Purification Methods
It is a good solid substitute for phosgene (using a third mol per mol). Crystallise it from pet ether (b 60-80o), wash it with anhydrous cold Et2O, de-gas it at 200mm then dry at 0.1mm (over H2SO4). It has IR: max 900 and 1900 cm-1 . It is a lachrymator, is TOXIC and should be handled with gloves and in an efficient fume hood. [Hales et al. J Chem Soc 620 1957, Eckert & Forster Angew Chem, Int Ed Engl 26 894 1987, Aldrichimica Acta 21 47 1988, Beilstein 3 H 17, 3 I 8, 3 II 16, 3 III 36, 3 IV 33.]트리포스겐 준비 용품 및 원자재
원자재
준비 용품
리토나비르
4-Cyanophenyl isocyanate
3-Bromophenyl isocyanate
3-METHOXYPHENYL ISOCYANATE
2-CHLOROBENZYL CHLOROFORMATE
1-CHLORO-2-METHYLPROPYL CHLOROFORMATE
Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate
2,2,2-Trichloroethyl chloroformate
4-DIMETHYLAMINOPHENYL ISOCYANATE
2-Methoxyphenyl isocyanate
N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine
BIS(4-NITROPHENYL) CARBONATE
Pentyl isocyanate
클로로탄산 페닐에스테르
4-Methylbenzyl isocyanate
H-LYS(2-CL-Z)-OH
(S)-3-TERT-BUTYL-2,5-PIPERAZINEDIONE
5-FLUORO-2H-3,1-BENZOXAZINE-2,4(1H)-DIONE
2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
4-(2-케토-1-벤지미다졸린일)피페리딘
2-클로로페닐이소시아네이트
(S)-(-)-4-tert-Butyloxazolidine-2,5-dione
DIRECT YELLOW 50
3-(Trifluoromethyl)phenyl isocyanate
4-메톡시페닐이소시아네이트
3,5-DIMETHYLISOXAZOL-4-YL ISOCYANATE
2-FLUOROPHENYL ISOCYANATE
2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
나프틸이소시아네이트
3,4-(METHYLENEDIOXY)PHENYL ISOCYANATE
2-브로모티오펜5-카복시알데히드
4-Fluorophenyl isocyanate
(1-METHYL-1H-PYRROL-2-YL)METHYLAMINE
2-NAPHTHYL ISOCYANATE
C.I. 다이렉트 레드 75
1,5-디페닐카보노히드라지드
4-Methoxybenzyl isocyanate
3-FLUOROPHENYL ISOCYANATE
3,4-(METHYLENEDIOXY)PHENYL ISOCYANATE
트리포스겐 공급 업체
글로벌( 471)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Anhui Royal Chemical Co., Ltd. | +86-25-86655873 +8613962173137 |
marketing@royal-chem.com | China | 142 | 55 |
| Jiangsu Guotai Guomian Trading Co. Ltd. | +86-512-58916079 +86-13601562190 |
pharmachem@gtgmt.com | China | 148 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2967 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
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